| The AT04A vaccine against proprotein convertase subtilisin/kexin type 9 reduces total cholesterol, vascular inflammation, and atherosclerosis in APOE* 3Leiden. CETP mice C Landlinger, MG Pouwer, C Juno, JWA van der Hoorn, EJ Pieterman, ... European heart journal 38 (32), 2499-2507, 2017 | 217 | 2017 |
| The BCR-ABL1 inhibitors imatinib and ponatinib decrease plasma cholesterol and atherosclerosis, and nilotinib and ponatinib activate coagulation in a translational mouse model MG Pouwer, EJ Pieterman, L Verschuren, MPM Caspers, C Kluft, ... Frontiers in cardiovascular medicine 5, 55, 2018 | 59 | 2018 |
| Alirocumab, evinacumab, and atorvastatin triple therapy regresses plaque lesions and improves lesion composition in mice [S] MG Pouwer, EJ Pieterman, N Worms, N Keijzer, JW Jukema, J Gromada, ... Journal of Lipid Research 61 (3), 365-375, 2020 | 55 | 2020 |
| Dose effects of ammonium perfluorooctanoate on lipoprotein metabolism in APOE* 3-Leiden. CETP mice MG Pouwer, EJ Pieterman, SC Chang, GW Olsen, MPM Caspers, ... Toxicological Sciences 168 (2), 519-534, 2019 | 24 | 2019 |
| Inflammatory cytokine oncostatin M induces endothelial activation in macro-and microvascular endothelial cells and in APOE* 3Leiden. CETP mice D van Keulen, MG Pouwer, G Pasterkamp, AJ van Gool, ... PLoS One 13 (10), e0204911, 2018 | 19 | 2018 |
| Inflammatory cytokine oncostatin M induces endothelial activation in macro-and microvascular endothelial cells and in APOE* 3Leiden. CETP mice D van Keulen, MG Pouwer, G Pasterkamp, AJ van Gool, ... PLoS One 13 (10), e0204911, 2018 | 19 | 2018 |
| Comment on “Hypercholesterolemia with consumption of PFOA-laced Western diets is dependent on strain and sex of mice” by Rebholz SL et al. Toxicol. Rep. 2016 (3) 46–54 HMG Princen, MG Pouwer, EJ Pieterman Toxicology reports 3, 306, 2016 | 17 | 2016 |
| Novel high-intensive cholesterol-lowering therapies do not ameliorate knee OA development in humanized dyslipidemic mice Y van Gemert, AE Kozijn, MG Pouwer, NNL Kruisbergen, ... Osteoarthritis and Cartilage 29 (9), 1314-1323, 2021 | 13 | 2021 |
| The APOE 3-Leiden Heterozygous Glucokinase Knockout Mouse as Novel Translational Disease Model for Type 2 Diabetes, Dyslipidemia, and Diabetic Atherosclerosis MG Pouwer, SE Heinonen, M Behrendt, AC Andréasson, A van Koppen, ... Journal of Diabetes Research 2019, 2019 | 13 | 2019 |
| Oncostatin M reduces atherosclerosis development in APOE* 3Leiden. CETP mice and is associated with increased survival probability in humans D Keulen, MG Pouwer, V Emilsson, LP Matic, EJ Pieterman, U Hedin, ... PLoS One 14 (8), e0221477, 2019 | 10 | 2019 |
| The tyrosine kinase inhibitor nilotinib targets the discoidin domain receptor DDR2 in calcific aortic valve stenosis M Carracedo, SC Pawelzik, G Artiach, MG Pouwer, O Plunde, ... British Journal of Pharmacology 179 (19), 4709-4721, 2022 | 6 | 2022 |
| Expression and clinical relevance of paired box protein 7 and sex determining region Y-box 2 in canine corticotroph pituitary adenomas SJ van Rijn, MG Pouwer, MA Tryfonidou, GCM Grinwis, JEE van der Bend, ... The Veterinary Journal 204 (3), 315-321, 2015 | 6 | 2015 |
| Triple treatment with alirocumab and evinacumab on top of atorvastatin regresses lesion size and improves plaque phenotype in Apoe* 3leiden. Cetp mice M Pouwer, EJ Pieterman, N Worms, N Keijzer, JW Jukema, V Gusarova, ... Atherosclerosis 287, e12, 2019 | 1 | 2019 |
| Cardiovascular safety of BCR-ABL1 tyrosine kinase inhibitors: imatinib and ponatinib decrease plasma cholesterol and atherosclerosis in APOE3* Leiden. CETP Mice M Pouwer, E Pieterman, L Verschuren, M Caspers, K Kluft, R Garcia, ... Atherosclerosis 263, e29-e30, 2017 | 1 | 2017 |
| The APOE* 3Leiden. GK+/-mouse as novel translational model for dyslipidemia, type 2 diabetes and macrovascular complications M Pouwer, S Heinonen, M Behrendt, AC Andréasson, E Pieterman, ... Atherosclerosis 252, e226-e227, 2016 | 1 | 2016 |
| Affitope-based anti-PCSK9 (proprotein convertase subtilisin/kexin type 9) vaccine (AT04A) reduces atherosclerosis in APOE* 3Leiden. CETP mice G Galabova, C Juno, JWA van der Hoorn, EJ Pieterman, M Pouwer, ... Atherosclerosis 252, e253-e254, 2016 | 1 | 2016 |
| A Real-world Toxicity Atlas Shows that Adverse Events of Combination Therapies Commonly Result in Additive Interactions A Küçükosmanoglu, S Scoarta, M Houweling, N Spinu, T Wijnands, ... Clinical Cancer Research 30 (8), 1685-1695, 2024 | | 2024 |
| A Roadmap to Use Nonstructured Data to Discover Multitarget Cancer Therapies S Scoarta, A Küçükosmanoglu, F Bindt, M Pouwer, BA Westerman JCO clinical cancer informatics 7, e2200096, 2023 | | 2023 |
| Novel high-intensity cholesterol-lowering therapies do not ameliorate knee osteoarthritis development in humanized dyslipidemic mice Y van Gemert, AE Kozijn, MG Pouwer, NNL Kruisbergen, ... Radical Metabolism 29 (9), 111, 2023 | | 2023 |
| High-intensive therapeutic lowering of systemic cholesterol does not ameliorate osteoarthritis development in knee joints of humanized dyslipidemic mice Y van Gemert, AE Kozijn, MG Pouwer, NN Kruisbergen, ... Osteoarthritis and Cartilage 28, S66, 2020 | | 2020 |
