Human embryonic stem cells have constitutively active Bax at the Golgi and are primed to undergo rapid apoptosis R Dumitru, V Gama, BM Fagan, JJ Bower, V Swahari, LH Pevny, ... Molecular cell 46 (5), 573-583, 2012 | 175 | 2012 |
Bax-inhibiting peptides derived from Ku70 and cell-penetrating pentapeptides JA Gomez, V Gama, T Yoshida, W Sun, P Hayes, K Leskov, D Boothman, ... Biochemical Society Transactions 35 (4), 797-801, 2007 | 122 | 2007 |
Bax-inhibiting peptide derived from mouse and rat Ku70 T Yoshida, I Tomioka, T Nagahara, T Holyst, M Sawada, P Hayes, ... Biochemical and biophysical research communications 321 (4), 961-966, 2004 | 115 | 2004 |
Bax-inhibiting peptide protects cells from polyglutamine toxicity caused by Ku70 acetylation Y Li, T Yokota, V Gama, T Yoshida, JA Gomez, K Ishikawa, H Sasaguri, ... Cell Death & Differentiation 14 (12), 2058-2067, 2007 | 111 | 2007 |
Mortalin, apoptosis, and neurodegeneration C Londono, C Osorio, V Gama, O Alzate Biomolecules 2 (1), 143-164, 2012 | 87 | 2012 |
The E3 ligase PARC mediates the degradation of cytosolic cytochrome c to promote survival in neurons and cancer cells V Gama, V Swahari, J Schafer, AJ Kole, A Evans, Y Huang, A Cliffe, ... Science signaling 7 (334), ra67-ra67, 2014 | 82 | 2014 |
Cell-penetrating penta-peptides (CPP5s): measurement of cell entry and protein-transduction activity JA Gomez, J Chen, J Ngo, D Hajkova, IJ Yeh, V Gama, M Miyagi, ... Pharmaceuticals 3 (12), 3594-3613, 2010 | 81 | 2010 |
Sensitivity of Leishmania viannia panamensis to Pentavalent Antimony Is Correlated with the Formation of Cleavable DNA-Protein Complexes A Lucumi, S Robledo, V Gama, NG Saravia Antimicrobial Agents and Chemotherapy 42 (8), 1990-1995, 1998 | 77 | 1998 |
A non-apoptotic function of MCL-1 in promoting pluripotency and modulating mitochondrial dynamics in stem cells ML Rasmussen, LA Kline, KP Park, NA Ortolano, AI Romero-Morales, ... Stem cell reports 10 (3), 684-692, 2018 | 69 | 2018 |
Hdm2 is a ubiquitin ligase of Ku70-Akt promotes cell survival by inhibiting Hdm2-dependent Ku70 destabilization V Gama, JA Gomez, LD Mayo, MW Jackson, D Danielpour, K Song, ... Cell Death & Differentiation 16 (5), 758-769, 2009 | 56 | 2009 |
Common molecular mechanisms of SLC6A1 variant-mediated neurodevelopmental disorders in astrocytes and neurons F Mermer, S Poliquin, K Rigsby, A Rastogi, W Shen, A Romero-Morales, ... Brain 144 (8), 2499-2512, 2021 | 50 | 2021 |
MCL-1 inhibition by selective BH3 mimetics disrupts mitochondrial dynamics causing loss of viability and functionality of human cardiomyocytes ML Rasmussen, N Taneja, AC Neininger, L Wang, GL Robertson, ... IScience 23 (4), 2020 | 49 | 2020 |
Precise tuning of cortical contractility regulates cell shape during cytokinesis N Taneja, MR Bersi, SM Baillargeon, AM Fenix, JA Cooper, R Ohi, ... Cell reports 31 (1), 2020 | 49 | 2020 |
Bax deficiency prolongs cerebellar neurogenesis, accelerates medulloblastoma formation and paradoxically increases both malignancy and differentiation I Garcia, AJ Crowther, V Gama, C Ryan Miller, M Deshmukh, TR Gershon Oncogene 32 (18), 2304-2314, 2013 | 48 | 2013 |
Involvement of the ubiquitin pathway in decreasing Ku70 levels in response to drug-induced apoptosis V Gama, T Yoshida, JA Gomez, DP Basile, LD Mayo, AL Haas, ... Experimental cell research 312 (4), 488-499, 2006 | 42 | 2006 |
CRM1 protein-mediated regulation of nuclear clusterin (nCLU), an ionizing radiation-stimulated, Bax-dependent pro-death factor KS Leskov, S Araki, JP Lavik, JA Gomez, V Gama, ES Gonos, ... Journal of Biological Chemistry 286 (46), 40083-40090, 2011 | 41 | 2011 |
Wnt signaling and its impact on mitochondrial and cell cycle dynamics in pluripotent stem cells ML Rasmussen, NA Ortolano, AI Romero-Morales, V Gama Genes 9 (2), 109, 2018 | 39 | 2018 |
CLONAL DIVERSITY IN THE EXPRESSION AND STABILITY OF THE METASTATIC CAPABILITY OF LEISHMANIA GUYANENSIS IN THE GOLDEN HAMSTER JE Martínez, L Valderrama, V Gama, DA Leiby, NG Saravia Journal of Parasitology 86 (4), 792-799, 2000 | 39 | 2000 |
Tonic activation of Bax primes neural progenitors for rapid apoptosis through a mechanism preserved in medulloblastoma AJ Crowther, V Gama, A Bevilacqua, SX Chang, H Yuan, M Deshmukh, ... Journal of Neuroscience 33 (46), 18098-18108, 2013 | 34 | 2013 |
Human iPSC-derived cerebral organoids model features of Leigh syndrome and reveal abnormal corticogenesis AI Romero-Morales, GL Robertson, A Rastogi, ML Rasmussen, H Temuri, ... Development 149 (20), dev199914, 2022 | 32 | 2022 |