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Wei Gao
Wei Gao
Nature's Sunshine Products, Inc.
Adresse e-mail validée de natr.com
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The cyclic peptide ecumicin targeting ClpC1 is active against Mycobacterium tuberculosis in vivo
W Gao, JY Kim, JR Anderson, T Akopian, S Hong, YY Jin, O Kandror, ...
Antimicrobial agents and chemotherapy 59 (2), 880-889, 2015
1862015
Rufomycin targets ClpC1 proteolysis in Mycobacterium tuberculosis and M. abscessus
MP Choules, NM Wolf, H Lee, JR Anderson, EM Grzelak, Y Wang, R Ma, ...
Antimicrobial agents and chemotherapy 63 (3), 10.1128/aac. 02204-18, 2019
912019
Strategies in anti-Mycobacterium tuberculosis drug discovery based on phenotypic screening
EM Grzelak, MP Choules, W Gao, G Cai, B Wan, Y Wang, JB McAlpine, ...
The Journal of antibiotics 72 (10), 719-728, 2019
702019
Discovery and characterization of the tuberculosis drug lead ecumicin
W Gao, JY Kim, SN Chen, SH Cho, J Choi, BU Jaki, YY Jin, DC Lankin, ...
Organic letters 16 (23), 6044-6047, 2014
662014
Bioautography with TLC-MS/NMR for rapid discovery of anti-tuberculosis lead compounds from natural sources
EM Grzelak, C Hwang, G Cai, JW Nam, MP Choules, W Gao, DC Lankin, ...
ACS infectious diseases 2 (4), 294-301, 2016
552016
High-resolution structure of ClpC1-rufomycin and ligand binding studies provide a framework to design and optimize anti-tuberculosis leads
NM Wolf, H Lee, MP Choules, GF Pauli, R Phansalkar, JR Anderson, ...
ACS infectious diseases 5 (6), 829-840, 2019
502019
Quality Control of Therapeutic Peptides by 1H NMR HiFSA Sequencing
MP Choules, J Bisson, W Gao, DC Lankin, JB McAlpine, M Niemitz, ...
The Journal of organic chemistry 84 (6), 3055-3073, 2019
262019
A 13-week low glycemic load diet and lifestyle modification program combining low glycemic load protein shakes and targeted nutraceuticals improved weight loss and cardio …
CJ Dahlberg, JJ Ou, JG Babish, JJ Lamb, S Eliason, H Brabazon, W Gao, ...
Canadian Journal of Physiology and Pharmacology 95 (12), 1414-1425, 2017
202017
Synergistic in vitro antioxidant activity and observational clinical trial of F105, a phytochemical formulation including Citrus bergamia, in subjects with moderate …
TML Babish JG, Dahlberg CJ, Ou JJ, Keller WJ, Gao W, Kaadige MR, Brabazon H ...
Can J Physiol Pharmacol. 94 (12), 1257-1266, 2016
192016
A low-glycemic, Mediterranean diet and lifestyle modification program with targeted nutraceuticals reduces body weight, improves cardiometabolic variables and longevity …
ML Tripp, CJ Dahlberg, S Eliason, JJ Lamb, JJ Ou, W Gao, J Bhandari, ...
Journal of medicinal food 22 (5), 479-489, 2019
152019
Structural Sequencing of Oligopeptides Aided by 1H Iterative Full-Spin Analysis
W Gao, JB McAlpine, MP Choules, JG Napolitano, DC Lankin, C Simmler, ...
Journal of natural products 80 (10), 2630-2643, 2017
122017
Computer-assisted 1H NMR analysis of the anti-tuberculosis drug lead ecumicin
W Gao, JG Napolitano, DC Lankin, JY Kim, YY Jin, H Lee, JW Suh, ...
Magnetic resonance in chemistry: MRC 55 (3), 239, 2017
112017
Cyclic peptide from Nonomuraea sp., process for the production thereof, and pharmaceutical composition for the prevention or treatment of mycobacteria related disease …
JW Kim, SW Lee, SJ Park, JW Suh, IA Lee, TM Yoon, JK Choi, JE Lee, ...
US Patent 9,090,667, 2015
82015
A rufomycin analogue is an anti-tuberculosis drug lead targeting CLPC1 with no cross resistance to ecumicin
M Choules, Y Yu, SH Cho, J Anderson, W Gao, L Klein, DC Lankin, ...
Planta Medica 81 (11), CL2, 2015
72015
Compositions and methods for acutley raising nitric oxide levels
ML Tripp, CJ Dahlberg, JG Babish, M Kaadige, W Gao
US Patent 11,241,406, 2022
42022
Phytocomplexes exhibiting multiple, synergistic antioxidant activities useful in foods, dietary supplements, cosmetics and pharmaceutical preparations
ML Tripp, CJ Dahlberg, JG Babish, W Gao, M Kaadige, S Krig, X Kou, ...
US Patent 10,434,131, 2019
42019
Methods and compositions to enhance metabolic detoxification systems
ML Tripp, CJ Dahlberg, JG Babish, J Lamb, JJ Ou, VR Konda, S Elison, ...
US Patent App. 16/761,489, 2021
22021
New insights on the structure of the anti-TB peptide H14: crystal structure, 1H NMR full spin analysis, and biosynthetic pathway
W Gao, JG Napolitano, JY Kim, IA Lee, JE Lee, J Choi, ...
Planta Medica 78 (11), PJ134, 2012
22012
Methods and compositions to improve weight loss and cardiometabolic health beyond diet and excercise
ML Tripp, CJ Dahlberg, JG Babish, J Lamb, JJ Ou, S Elison, W Gao, ...
US Patent 11,122,832, 2021
12021
High-resolution structure of Clpc1-Ntd-Rufomycin complex provides three-dimensional framework for optimization of cyclopeptide anti-Tb drug leads
N Wolf, H Lee, M Choules, L Klein, V Petukhova, M Tufano, R Phansalkar, ...
PROTEIN SCIENCE 27, 119-120, 2018
12018
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