SARS-CoV-2 Omicron variant: Antibody evasion and cryo-EM structure of spike protein–ACE2 complex D Mannar, JW Saville, X Zhu, SS Srivastava, AM Berezuk, KS Tuttle, ... Science 375 (6582), 760-764, 2022 | 516 | 2022 |
Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies X Zhu, D Mannar, SS Srivastava, AM Berezuk, JP Demers, JW Saville, ... PLoS biology 19 (4), e3001237, 2021 | 185 | 2021 |
Structural and biochemical rationale for enhanced spike protein fitness in delta and kappa SARS-CoV-2 variants JW Saville, D Mannar, X Zhu, SS Srivastava, AM Berezuk, JP Demers, ... Nature communications 13 (1), 742, 2022 | 76 | 2022 |
Structural analysis of receptor binding domain mutations in SARS-CoV-2 variants of concern that modulate ACE2 and antibody binding D Mannar, JW Saville, X Zhu, SS Srivastava, AM Berezuk, S Zhou, ... Cell reports 37 (12), 2021 | 74 | 2021 |
SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization D Mannar, JW Saville, Z Sun, X Zhu, MM Marti, SS Srivastava, ... Nature Communications 13 (1), 4696, 2022 | 39* | 2022 |
Sars-cov-2 omicron variant: Ace2 binding, cryo-em structure of spike protein-ace2 complex and antibody evasion D Mannar, JW Saville, X Zhu, SS Srivastava, AM Berezuk, KS Tuttle, ... BioRxiv, 2021.12. 19.473380, 2021 | 33 | 2021 |
SARS-CoV-2 Omicron Variant: ACE2 Binding D Mannar, JW Saville, X Zhu, SS Srivastava, AM Berezuk, KS Tuttle, ... Cryo-EM Structure of Spike Protein-ACE2 Complex and Antibody Evasion …, 2021 | 17 | 2021 |
Three-dimensional visualization of viral structure, entry, and replication underlying the spread of SARS-CoV-2 JW Saville, AM Berezuk, SS Srivastava, S Subramaniam Chemical reviews 122 (17), 14066-14084, 2022 | 16 | 2022 |
Structural analysis of receptor engagement and antigenic drift within the BA. 2 spike protein JW Saville, D Mannar, X Zhu, AM Berezuk, S Cholak, KS Tuttle, ... Cell Reports 42 (1), 2023 | 11 | 2023 |
PeptiQuick, a One-Step Incorporation of Membrane Proteins into Biotinylated Peptidiscs for Streamlined Protein Binding Assays JW Saville, L Troman, FD Van Hoa JoVE (Journal of Visualized Experiments), e60661, 2019 | 10 | 2019 |
Development and field validation of lidocaine-loaded castration bands for bovine pain mitigation JW Saville, JA Ross, T Trefz, C Schatz, H Matheson-Bird, B Ralston, ... Animals 10 (12), 2363, 2020 | 5 | 2020 |
Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives S Cholak, JW Saville, X Zhu, AM Berezuk, KS Tuttle, O Haji-Ghassemi, ... Structure 31 (7), 790-800. e4, 2023 | 4 | 2023 |
[GaX2(dmpe)2][GaX4] (X = Cl, Br, I): a synthetic, solid state, and computational study PA Gray, JW Saville, KD Krause, N Burford, R McDonald, MJ Ferguson Canadian Journal of Chemistry 95 (4), 346-350, 2017 | 3 | 2017 |
Potent and broad neutralization of SARS-CoV-2 variants of concern (VOCs) including omicron sub-lineages BA. 1 and BA. 2 by biparatopic human VH domains C Chen, JW Saville, MM Marti, A Schäfer, MH Cheng, D Mannar, X Zhu, ... Iscience 25 (8), 2022 | 1* | 2022 |
Altered receptor binding, antibody evasion and retention of T cell recognition by the SARS-CoV-2 XBB. 1.5 spike protein D Mannar, JW Saville, C Poloni, X Zhu, A Bezeruk, K Tidey, S Ahmed, ... Nature Communications 15 (1), 1854, 2024 | | 2024 |
Molecular mechanisms of SARS-CoV-2 variant spike proteins JW Saville University of British Columbia, 2023 | | 2023 |
Structure-Function Rationale for Enhanced Viral Fitness in SARS-CoV-2 Variants of Concern J Saville, D Mannar, X Zhu, W Li, A Berezuk, K Tuttle, S Cholak, ... Protein Science, 2023 | | 2023 |
Allosteric Modulation of RyR1 with Nucleotide Analogs S Cholak, J Saville, X Zhu, A Berezuk, O Haji-Ghassemi, K Tuttle, ... PROTEIN SCIENCE 32, 2023 | | 2023 |
SARS-CoV-2 Omicron Variant: ACE2 Binding, Cryo-EM Structure of Spike Protein-ACE2 Complex and Antibody Evasion (preprint) D Mannar, JW Saville, X Zhu, SS Srivastava, AM Berezuk, K Tuttle, ... | | 2021 |