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Yaqing Zhang
Yaqing Zhang
Adresse e-mail validée de umich.edu
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Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice
MA Collins, F Bednar, Y Zhang, JC Brisset, S Galbán, CJ Galbán, ...
The Journal of clinical investigation 122 (2), 639-653, 2012
8072012
Macrophage-released pyrimidines inhibit gemcitabine therapy in pancreatic cancer
CJ Halbrook, C Pontious, I Kovalenko, L Lapienyte, S Dreyer, HJ Lee, ...
Cell metabolism 29 (6), 1390-1399. e6, 2019
3302019
Myeloid cells are required for PD-1/PD-L1 checkpoint activation and the establishment of an immunosuppressive environment in pancreatic cancer
Y Zhang, A Velez-Delgado, E Mathew, D Li, FM Mendez, K Flannagan, ...
Gut 66 (1), 124-136, 2017
3162017
Regulatory T-cell depletion alters the tumor microenvironment and accelerates pancreatic carcinogenesis
Y Zhang, J Lazarus, NG Steele, W Yan, HJ Lee, ZC Nwosu, CJ Halbrook, ...
Cancer discovery 10 (3), 422-439, 2020
2712020
Interleukin-6 is required for pancreatic cancer progression by promoting MAPK signaling activation and oxidative stress resistance
Y Zhang, W Yan, MA Collins, F Bednar, S Rakshit, BR Zetter, BZ Stanger, ...
Cancer research 73 (20), 6359-6374, 2013
2532013
Canonical wnt signaling is required for pancreatic carcinogenesis
Y Zhang, JP Morris IV, W Yan, HK Schofield, A Gurney, DM Simeone, ...
Cancer research 73 (15), 4909-4922, 2013
2022013
Metastatic pancreatic cancer is dependent on oncogenic Kras in mice
MA Collins, JC Brisset, Y Zhang, F Bednar, J Pierre, KA Heist, CJ Galbán, ...
PloS one 7 (12), e49707, 2012
2002012
Inhibition of hedgehog signaling alters fibroblast composition in pancreatic cancer
NG Steele, G Biffi, SB Kemp, Y Zhang, D Drouillard, LJ Syu, Y Hao, ...
Clinical Cancer Research 27 (7), 2023-2037, 2021
1782021
Phosphorylation of BRAF by AMPK impairs BRAF-KSR1 association and cell proliferation
CH Shen, P Yuan, R Perez-Lorenzo, Y Zhang, SX Lee, Y Ou, JM Asara, ...
Molecular cell 52 (2), 161-172, 2013
1372013
Phenformin inhibits myeloid-derived suppressor cells and enhances the anti-tumor activity of PD-1 blockade in melanoma
SH Kim, M Li, S Trousil, Y Zhang, MP di Magliano, KD Swanson, B Zheng
Journal of Investigative Dermatology 137 (8), 1740-1748, 2017
1272017
Loss of the transcription factor GLI1 identifies a signaling network in the tumor microenvironment mediating KRAS oncogene-induced transformation
LD Mills, Y Zhang, RJ Marler, M Herreros-Villanueva, L Zhang, LL Almada, ...
Journal of Biological Chemistry 288 (17), 11786-11794, 2013
1262013
CD44 regulates pancreatic cancer invasion through MT1-MMP
W Jiang, Y Zhang, KT Kane, MA Collins, DM Simeone, MP di Magliano, ...
Molecular Cancer Research 13 (1), 9-15, 2015
1032015
Dosage-dependent regulation of pancreatic cancer growth and angiogenesis by hedgehog signaling
E Mathew, Y Zhang, AM Holtz, KT Kane, JY Song, BL Allen, ...
Cell reports 9 (2), 484-494, 2014
1032014
Apolipoprotein E promotes immune suppression in pancreatic cancer through NF-κB–mediated production of CXCL1
SB Kemp, ES Carpenter, NG Steele, KL Donahue, ZC Nwosu, A Pacheco, ...
Cancer research 81 (16), 4305-4318, 2021
912021
CD4+ T Lymphocyte Ablation Prevents Pancreatic Carcinogenesis in Mice
Y Zhang, W Yan, E Mathew, F Bednar, S Wan, MA Collins, RA Evans, ...
Cancer immunology research 2 (5), 423-435, 2014
912014
Differential contribution of pancreatic fibroblast subsets to the pancreatic cancer stroma
PE Garcia, M Adoumie, EC Kim, Y Zhang, MK Scales, YS El-Tawil, ...
Cellular and molecular gastroenterology and hepatology 10 (3), 581-599, 2020
702020
Pancreatic cancer is marked by complement-high blood monocytes and tumor-associated macrophages
SB Kemp, NG Steele, ES Carpenter, KL Donahue, GG Bushnell, ...
Life science alliance 4 (6), 2021
692021
ATDC induces an invasive switch in KRAS-induced pancreatic tumorigenesis
L Wang, H Yang, EV Abel, GM Ney, PL Palmbos, F Bednar, Y Zhang, ...
Genes & Development 29 (2), 171-183, 2015
652015
Interleukin 22 signaling regulates acinar cell plasticity to promote pancreatic tumor development in mice
MP Lanfranca, Y Zhang, A Girgis, S Kasselman, J Lazarus, I Kryczek, ...
Gastroenterology 158 (5), 1417-1432. e11, 2020
632020
Mitogen-activated protein kinase kinase activity maintains acinar-to-ductal metaplasia and is required for organ regeneration in pancreatitis
CJ Halbrook, HJ Wen, JM Ruggeri, KK Takeuchi, Y Zhang, ...
Cellular and molecular gastroenterology and hepatology 3 (1), 99-118, 2017
582017
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