Purmorphamine activates the Hedgehog pathway by targeting Smoothened S Sinha, JK Chen Nature chemical biology 2 (1), 29-30, 2006 | 453 | 2006 |
Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade JM Hyman, AJ Firestone, VM Heine, Y Zhao, CA Ocasio, K Han, M Sun, ... Proceedings of the National Academy of Sciences 106 (33), 14132-14137, 2009 | 354 | 2009 |
Light-controlled gene silencing in zebrafish embryos IA Shestopalov, S Sinha, JK Chen Nature chemical biology 3 (10), 650-651, 2007 | 249 | 2007 |
Multi-organ site metastatic reactivation mediated by non-canonical discoidin domain receptor 1 signaling H Gao, G Chakraborty, Z Zhang, I Akalay, M Gadiya, Y Gao, S Sinha, J Hu, ... Cell 166 (1), 47-62, 2016 | 219 | 2016 |
A Purine‐like Nickel(II) Base Pair for DNA C Switzer, S Sinha, PH Kim, BD Heuberger Angewandte Chemie International Edition 44 (10), 1529-1532, 2005 | 183 | 2005 |
The impact of microsatellite stability status in colorectal cancer R Gupta, S Sinha, RN Paul Current problems in cancer 42 (6), 548-559, 2018 | 120 | 2018 |
Versatile synthesis and rational design of caged morpholinos X Ouyang, IA Shestopalov, S Sinha, G Zheng, CLW Pitt, WH Li, AJ Olson, ... Journal of the American Chemical Society 131 (37), 13255-13269, 2009 | 120 | 2009 |
Activation of ras oncogene in aflatoxin-induced rat liver carcinogenesis. S Sinha, C Webber, CJ Marshall, MA Knowles, A Proctor, NC Barrass, ... Proceedings of the National Academy of Sciences 85 (11), 3673-3677, 1988 | 117 | 1988 |
The Rho GTPase Rnd1 suppresses mammary tumorigenesis and EMT by restraining Ras-MAPK signalling T Okada, S Sinha, I Esposito, G Schiavon, MA López-Lago, W Su, ... Nature cell biology 17 (1), 81-94, 2015 | 113 | 2015 |
Coordinated regulation of p53 apoptotic targets BAX and PUMA by SMAR1 through an identical MAR element S Sinha, SK Malonia, SPK Mittal, K Singh, S Kadreppa, R Kamat, ... The EMBO journal 29 (4), 830-842, 2010 | 79 | 2010 |
Protective role of curcumin against nicotine-induced genotoxicity on rat liver under restricted dietary protein G Bandyopadhyaya, S Sinha, BD Chattopadhyay, A Chakraborty European journal of pharmacology 588 (2-3), 151-157, 2008 | 69 | 2008 |
Transformation related expression of glutathione-S-transferase P in rat liver cells C Power, S Sinha, C Webber, MM Manson, GE Neal Carcinogenesis 8 (6), 797-801, 1987 | 66 | 1987 |
Reductive Heck coupling: an efficient approach toward the iboga alkaloids. Synthesis of ibogamine, epiibogamine and iboga analogs GK Jana, S Sinha Tetrahedron Letters 53 (13), 1671-1674, 2012 | 47 | 2012 |
The imidazopyridine derivative JK184 reveals dual roles for microtubules in Hedgehog signaling T Cupido, PG Rack, AJ Firestone, JM Hyman, K Han, S Sinha, CA Ocasio, ... Angewandte Chemie 121 (13), 2357-2360, 2009 | 44 | 2009 |
Total synthesis of ibogaine, epiibogaine and their analogues GK Jana, S Sinha Tetrahedron 68 (35), 7155-7165, 2012 | 43 | 2012 |
The prop-2-ynyloxy carbonyl function (POC): A new amino-protecting group removable from sulfur-containing peptides by ultrasonic irradiation with tetrathiomolybdate under mild … S Sinha, P Ilankumaran, S Chandrasekaran Tetrahedron Letters 40 (4), 771-774, 1999 | 40 | 1999 |
Gene regulation by SMAR1: Role in cellular homeostasis and cancer SK Malonia, S Sinha, P Lakshminarasimhan, K Singh, A Jalota-Badhwar, ... Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1815 (1), 1-12, 2011 | 38 | 2011 |
Discovery of hedgehog antagonists for cancer therapy H Khatra, C Bose, S Sinha Current medicinal chemistry 24 (19), 2033-2058, 2017 | 36 | 2017 |
Progress in the synthesis of iboga-alkaloids and their congeners GK Jana, S Paul, S Sinha Organic Preparations and Procedures International 43 (6), 541-573, 2011 | 35 | 2011 |
One pot conversion of alcohols to disulfides mediated by benzyltriethylammonium tetrathiomolybdate S Sinha, P Ilankumaran, S Chandrasekaran Tetrahedron 55 (51), 14769-14776, 1999 | 34 | 1999 |