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Surajit Sinha
Surajit Sinha
Professor of organic chemistry IACS
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Purmorphamine activates the Hedgehog pathway by targeting Smoothened
S Sinha, JK Chen
Nature chemical biology 2 (1), 29-30, 2006
4532006
Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade
JM Hyman, AJ Firestone, VM Heine, Y Zhao, CA Ocasio, K Han, M Sun, ...
Proceedings of the National Academy of Sciences 106 (33), 14132-14137, 2009
3542009
Light-controlled gene silencing in zebrafish embryos
IA Shestopalov, S Sinha, JK Chen
Nature chemical biology 3 (10), 650-651, 2007
2492007
Multi-organ site metastatic reactivation mediated by non-canonical discoidin domain receptor 1 signaling
H Gao, G Chakraborty, Z Zhang, I Akalay, M Gadiya, Y Gao, S Sinha, J Hu, ...
Cell 166 (1), 47-62, 2016
2192016
A Purine‐like Nickel(II) Base Pair for DNA
C Switzer, S Sinha, PH Kim, BD Heuberger
Angewandte Chemie International Edition 44 (10), 1529-1532, 2005
1832005
The impact of microsatellite stability status in colorectal cancer
R Gupta, S Sinha, RN Paul
Current problems in cancer 42 (6), 548-559, 2018
1202018
Versatile synthesis and rational design of caged morpholinos
X Ouyang, IA Shestopalov, S Sinha, G Zheng, CLW Pitt, WH Li, AJ Olson, ...
Journal of the American Chemical Society 131 (37), 13255-13269, 2009
1202009
Activation of ras oncogene in aflatoxin-induced rat liver carcinogenesis.
S Sinha, C Webber, CJ Marshall, MA Knowles, A Proctor, NC Barrass, ...
Proceedings of the National Academy of Sciences 85 (11), 3673-3677, 1988
1171988
The Rho GTPase Rnd1 suppresses mammary tumorigenesis and EMT by restraining Ras-MAPK signalling
T Okada, S Sinha, I Esposito, G Schiavon, MA López-Lago, W Su, ...
Nature cell biology 17 (1), 81-94, 2015
1132015
Coordinated regulation of p53 apoptotic targets BAX and PUMA by SMAR1 through an identical MAR element
S Sinha, SK Malonia, SPK Mittal, K Singh, S Kadreppa, R Kamat, ...
The EMBO journal 29 (4), 830-842, 2010
792010
Protective role of curcumin against nicotine-induced genotoxicity on rat liver under restricted dietary protein
G Bandyopadhyaya, S Sinha, BD Chattopadhyay, A Chakraborty
European journal of pharmacology 588 (2-3), 151-157, 2008
692008
Transformation related expression of glutathione-S-transferase P in rat liver cells
C Power, S Sinha, C Webber, MM Manson, GE Neal
Carcinogenesis 8 (6), 797-801, 1987
661987
Reductive Heck coupling: an efficient approach toward the iboga alkaloids. Synthesis of ibogamine, epiibogamine and iboga analogs
GK Jana, S Sinha
Tetrahedron Letters 53 (13), 1671-1674, 2012
472012
The imidazopyridine derivative JK184 reveals dual roles for microtubules in Hedgehog signaling
T Cupido, PG Rack, AJ Firestone, JM Hyman, K Han, S Sinha, CA Ocasio, ...
Angewandte Chemie 121 (13), 2357-2360, 2009
442009
Total synthesis of ibogaine, epiibogaine and their analogues
GK Jana, S Sinha
Tetrahedron 68 (35), 7155-7165, 2012
432012
The prop-2-ynyloxy carbonyl function (POC): A new amino-protecting group removable from sulfur-containing peptides by ultrasonic irradiation with tetrathiomolybdate under mild …
S Sinha, P Ilankumaran, S Chandrasekaran
Tetrahedron Letters 40 (4), 771-774, 1999
401999
Gene regulation by SMAR1: Role in cellular homeostasis and cancer
SK Malonia, S Sinha, P Lakshminarasimhan, K Singh, A Jalota-Badhwar, ...
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1815 (1), 1-12, 2011
382011
Discovery of hedgehog antagonists for cancer therapy
H Khatra, C Bose, S Sinha
Current medicinal chemistry 24 (19), 2033-2058, 2017
362017
Progress in the synthesis of iboga-alkaloids and their congeners
GK Jana, S Paul, S Sinha
Organic Preparations and Procedures International 43 (6), 541-573, 2011
352011
One pot conversion of alcohols to disulfides mediated by benzyltriethylammonium tetrathiomolybdate
S Sinha, P Ilankumaran, S Chandrasekaran
Tetrahedron 55 (51), 14769-14776, 1999
341999
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