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Fabrice Jaffré, PhD. Assistant Professor of Cell and Developmental Biology
Fabrice Jaffré, PhD. Assistant Professor of Cell and Developmental Biology
Weill Cornell Medical College
Adresse e-mail validée de med.cornell.edu - Page d'accueil
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A human pluripotent stem cell-based platform to study SARS-CoV-2 tropism and model virus infection in human cells and organoids
L Yang, Y Han, BE Nilsson-Payant, V Gupta, P Wang, X Duan, X Tang, ...
Cell stem cell 27 (1), 125-136. e7, 2020
6502020
Stimulating healthy tissue regeneration by targeting the 5-HT2B receptor in chronic liver disease
MR Ebrahimkhani, F Oakley, LB Murphy, J Mann, A Moles, MJ Perugorria, ...
Nature medicine 17 (12), 1668-1673, 2011
2252011
Overexpression of the Serotonin 5-HT2B Receptor in Heart Leads to Abnormal Mitochondrial Function and Cardiac Hypertrophy
CG Nebigil, F Jaffré, N Messaddeq, P Hickel, L Monassier, JM Launay, ...
Circulation 107 (25), 3223-3229, 2003
1722003
Serotonin and angiotensin receptors in cardiac fibroblasts coregulate adrenergic-dependent cardiac hypertrophy
F Jaffré, P Bonnin, J Callebert, H Debbabi, V Setola, S Doly, L Monassier, ...
Circulation research 104 (1), 113-123, 2009
1672009
Involvement of the Serotonin 5-HT2B Receptor in Cardiac Hypertrophy Linked to Sympathetic Stimulation: Control of Interleukin-6, Interleukin-1β, and Tumor …
F Jaffré, J Callebert, A Sarre, N Etienne, CG Nebigil, JM Launay, ...
Circulation 110 (8), 969-974, 2004
1672004
β-adrenergic receptor stimulation transactivates protease-activated receptor 1 via matrix metalloproteinase 13 in cardiac cells
F Jaffré, AE Friedman, Z Hu, N Mackman, BC Blaxall
Circulation 125 (24), 2993-3003, 2012
992012
Cyclophilin A Promotes Cardiac Hypertrophy in Apolipoprotein E–Deficient Mice
K Satoh, P Nigro, A Zeidan, NN Soe, F Jaffré, M Oikawa, MR O'Dell, Z Cui, ...
Arteriosclerosis, thrombosis, and vascular biology 31 (5), 1116-1123, 2011
972011
RhoA signaling in cardiomyocytes protects against stress-induced heart failure but facilitates cardiac fibrosis
J Lauriol, K Keith, F Jaffré, A Couvillon, A Saci, SA Goonasekera, ...
Science signaling 7 (348), ra100-ra100, 2014
912014
Serotonin 5-HT2B Receptor Blockade Prevents Reactive Oxygen Species–Induced Cardiac Hypertrophy in Mice
L Monassier, MA Laplante, F Jaffré, P Bousquet, L Maroteaux, ...
Hypertension 52 (2), 301-307, 2008
732008
Inborn errors of OAS–RNase L in SARS-CoV-2–related multisystem inflammatory syndrome in children
D Lee, J Le Pen, A Yatim, B Dong, Y Aquino, M Ogishi, R Pescarmona, ...
Science 379 (6632), eabo3627, 2022
642022
Inducible pluripotent stem cell–derived cardiomyocytes reveal aberrant extracellular regulated kinase 5 and mitogen-activated protein kinase kinase 1/2 signaling concomitantly …
F Jaffré, CL Miller, A Schänzer, T Evans, AE Roberts, A Hahn, ...
Circulation 140 (3), 207-224, 2019
522019
An immuno-cardiac model for macrophage-mediated inflammation in COVID-19 hearts
L Yang, Y Han, F Jaffre, BE Nilsson-Payant, Y Bram, P Wang, J Zhu, ...
Circulation research 129 (1), 33-46, 2021
472021
The role of the protein tyrosine phosphatase SHP2 in cardiac development and disease
J Lauriol, F Jaffre, MI Kontaridis
Seminars in cell & developmental biology 37, 73-81, 2015
472015
Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2
L Yang, BE Nilsson-Payant, Y Han, F Jaffré, J Zhu, P Wang, T Zhang, ...
Stem cell reports 16 (9), 2274-2288, 2021
452021
BR tenOever, T. Evans, RE Schwartz, S. Chen, A human pluripotent stem cell-based platform to study SARS-CoV-2 tropism and model virus infection in human cells and organoids
L Yang, Y Han, BE Nilsson-Payant, V Gupta, P Wang, X Duan, X Tang, ...
Cell stem cell 27 (125-136), e7, 2020
212020
Modeling polymorphic ventricular tachycardia at rest using patient-specific induced pluripotent stem cell-derived cardiomyocytes
Y Sleiman, M Souidi, R Kumar, E Yang, F Jaffré, T Zhou, A Bernardin, ...
EBioMedicine 60, 2020
192020
SARS-CoV-2 infected cardiomyocytes recruit monocytes by secreting CCL2
S Chen, L Yang, B Nilsson-Payant, Y Han, F Jaffré, J Zhu, P Wang, ...
Research Square, rs. 3. rs-94634, 2020
182020
The 5-HT2B receptor: a main cardio-pulmonary target of serotonin
N Etienne, B Schaerlinger, F Jaffré, L Maroteaux
Journal de la Societe de Biologie 198 (1), 22-29, 2004
172004
Generation of an induced pluripotent stem cell line (TRNDi003-A) from a Noonan syndrome with multiple lentigines (NSML) patient carrying a p. Q510P mutation in the PTPN11 gene
R Li, A Baskfield, Y Lin, J Beers, J Zou, C Liu, F Jaffré, AE Roberts, ...
Stem cell research 34, 101374, 2019
122019
iPSC-derived cardiomyocytes reveal aberrant ERK5 and MEK1/2 signaling concomitantly promote hypertrophic cardiomyopathy in RAF1-associated noonan syndrome
F Jaffré, CL Miller, A Schänzer, T Evans, AE Roberts, A Hahn, ...
Circulation 140 (3), 207, 2019
62019
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