| An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations U Dube, JL Del-Aguila, Z Li, JP Budde, S Jiang, S Hsu, L Ibanez, ... Nature Neuroscience, 1-10, 2019 | 264 | 2019 |
| The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer’s disease risk Y Deming, F Filipello, F Cignarella, C Cantoni, S Hsu, R Mikesell, Z Li, ... Science translational medicine 11 (505), eaau2291, 2019 | 206 | 2019 |
| A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain JL Del-Aguila, Z Li, U Dube, KA Mihindukulasuriya, JP Budde, ... Alzheimer's research & therapy 11 (1), 1-16, 2019 | 154 | 2019 |
| Species-dependent posttranscriptional regulation of NOS1 by FMRP in the developing cerebral cortex KY Kwan, MMS Lam, MB Johnson, U Dube, S Shim, MR Rašin, ... Cell 149 (4), 899-911, 2012 | 151 | 2012 |
| Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders C Yang, FHG Farias, L Ibanez, A Suhy, B Sadler, MV Fernandez, F Wang, ... Nature neuroscience 24 (9), 1302-1312, 2021 | 133* | 2021 |
| APOE genotype regulates pathology and disease progression in synucleinopathy AA Davis, CE Inman, ZM Wargel, U Dube, BM Freeberg, A Galluppi, ... Science translational medicine 12 (529), eaay3069, 2020 | 124 | 2020 |
| TREM2 brain transcript-specific studies in AD and TREM2 mutation carriers JL Del-Aguila, BA Benitez, Z Li, U Dube, KA Mihindukulasuriya, JP Budde, ... Molecular neurodegeneration 14, 1-13, 2019 | 67 | 2019 |
| Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels L Ibanez, U Dube, B Saef, J Budde, K Black, A Medvedeva, JL Del-Aguila, ... BMC neurology 17, 1-9, 2017 | 65 | 2017 |
| The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion Z Li, FHG Farias, U Dube, JL Del-Aguila, KA Mihindukulasuriya, ... Acta neuropathologica 139 (1), 45-61, 2020 | 55 | 2020 |
| Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP S Jiang, N Wen, Z Li, U Dube, J Del Aguila, J Budde, R Martinez, S Hsu, ... Translational psychiatry 8 (1), 265, 2018 | 51 | 2018 |
| Genetic variants associated with Alzheimer’s disease confer different cerebral cortex cell-type population structure Z Li, JL Del-Aguila, U Dube, J Budde, R Martinez, K Black, Q Xiao, ... Genome medicine 10, 1-19, 2018 | 50 | 2018 |
| Analysis of neurodegenerative Mendelian genes in clinically diagnosed Alzheimer Disease MV Fernandez, JH Kim, JP Budde, K Black, A Medvedeva, B Saef, ... PLoS genetics 13 (11), e1007045, 2017 | 30 | 2017 |
| Polygenic risk scores in neurodegenerative diseases: a review L Ibanez, FHG Farias, U Dube, KA Mihindukulasuriya, O Harari Current Genetic Medicine Reports 7, 22-29, 2019 | 29 | 2019 |
| Overlapping genetic architecture between Parkinson disease and melanoma U Dube, L Ibanez, JP Budde, BA Benitez, AA Davis, O Harari, MM Iles, ... Acta Neuropathologica 139 (2), 347-364, 2020 | 24 | 2020 |
| Pleiotropic effects of variants in dementia genes in Parkinson disease L Ibanez, U Dube, AG Davis, MV Fernandez, J Budde, B Cooper, ... Frontiers in neuroscience 12, 230, 2018 | 22 | 2018 |
| Overlap in the Genetic Architecture of Stroke Risk, Early Neurological Changes, and Cardiovascular Risk Factors L Ibanez, L Heitsch, U Dube, FHG Farias, J Budde, K Bergmann, ... Stroke 50 (6), 1339-1345, 2019 | 19 | 2019 |
| Examination of the effect of rare variants in TREM2, ABI3, and PLCG2 in LOAD through multiple phenotypes C Olive, L Ibanez, FHG Farias, F Wang, JP Budde, JB Norton, J Gentsch, ... Journal of Alzheimer's Disease 77 (4), 1469-1482, 2020 | 18 | 2020 |
| Use of medical care biases associations between Parkinson disease and other medical conditions A Gross, BA Racette, A Camacho-Soto, U Dube, SS Nielsen Neurology 90 (24), e2155-e2165, 2018 | 17 | 2018 |
| Metabolomic and lipidomic signatures in autosomal dominant and late‐onset Alzheimer's disease brains BC Novotny, MV Fernandez, C Wang, JP Budde, K Bergmann, ... Alzheimer's & Dementia, 2021 | 13 | 2021 |
| Well Water and Parkinson’s Disease in Medicare Beneficiaries: A Nationwide Case-Control Study MR Silver, BA Racette, U Dube, IM Faust, S Searles Nielsen Journal of Parkinson's disease 10 (2), 693-705, 2020 | 13 | 2020 |
Carlos CruchagaProfessor. NeuroGenomics and Informatics Center DirectorVerified email at wustl.edu
