The epithelial-mesenchymal transition (EMT) regulatory factor SLUG (SNAI2) is a downstream target of SPARC and AKT in promoting melanoma cell invasion N Fenouille, M Tichet, M Dufies, A Pottier, A Mogha, JK Soo, S Rocchi, ... PloS one 7 (7), e40378, 2012 | 242 | 2012 |
Autophagy is required for CSF-1–induced macrophagic differentiation and acquisition of phagocytic functions A Jacquel, S Obba, L Boyer, M Dufies, G Robert, P Gounon, E Lemichez, ... Blood, The Journal of the American Society of Hematology 119 (19), 4527-4531, 2012 | 164 | 2012 |
Resistance to sunitinib in renal clear cell carcinoma results from sequestration in lysosomes and inhibition of the autophagic flux S Giuliano, Y Cormerais, M Dufies, R Grépin, P Colosetti, A Belaid, ... Autophagy 11 (10), 1891-1904, 2015 | 131 | 2015 |
Mechanisms of AXL overexpression and function in Imatinib-resistant chronic myeloid leukemia cells M Dufies, A Jacquel, N Belhacene, G Robert, T Cluzeau, F Luciano, ... Oncotarget 2 (11), 874, 2011 | 127 | 2011 |
Sunitinib stimulates expression of VEGFC by tumor cells and promotes lymphangiogenesis in clear cell renal cell carcinomas M Dufies, S Giuliano, D Ambrosetti, A Claren, PD Ndiaye, M Mastri, ... Cancer research 77 (5), 1212-1226, 2017 | 99 | 2017 |
Gene expression profiling of imatinib and PD166326-resistant CML cell lines identifies Fyn as a gene associated with resistance to BCR-ABL inhibitors S Grosso, A Puissant, M Dufies, P Colosetti, A Jacquel, K Lebrigand, ... Molecular cancer therapeutics 8 (7), 1924-1933, 2009 | 94 | 2009 |
Persistent activation of the Fyn/ERK kinase signaling axis mediates imatinib resistance in chronic myelogenous leukemia cells through upregulation of intracellular SPARC N Fenouille, A Puissant, M Dufies, G Robert, A Jacquel, M Ohanna, ... Cancer research 70 (23), 9659-9670, 2010 | 72 | 2010 |
Synthesis and anti-cancer activities of new sulfonamides 4-substituted-triazolyl nucleosides S Alaoui, M Dufies, M Driowya, L Demange, K Bougrin, G Robert, ... Bioorganic & Medicinal Chemistry Letters 27 (9), 1989-1992, 2017 | 58 | 2017 |
Synthesis and biological evaluation of 3-amino-1, 2, 4-triazole derivatives as potential anticancer compounds O Grytsai, O Valiashko, M Penco-Campillo, M Dufies, A Hagege, ... Bioorganic chemistry 104, 104271, 2020 | 56 | 2020 |
The two glycolytic markers GLUT1 and MCT1 correlate with tumor grade and survival in clear-cell renal cell carcinoma D Ambrosetti, M Dufies, B Dadone, M Durand, D Borchiellini, J Amiel, ... PloS one 13 (2), e0193477, 2018 | 56 | 2018 |
The p53/p21Cip1/ Waf1 pathway mediates the effects of SPARC on melanoma cell cycle progression N Fenouille, G Robert, M Tichet, A Puissant, M Dufies, S Rocchi, ... Pigment cell & melanoma research 24 (1), 219-232, 2011 | 53 | 2011 |
The anti-apoptotic Bcl-B protein inhibits BECN1-dependent autophagic cell death G Robert, C Gastaldi, A Puissant, A Hamouda, A Jacquel, M Dufies, ... Autophagy 8 (4), 637-649, 2012 | 52 | 2012 |
Imatinib triggers mesenchymal-like conversion of CML cells associated with increased aggressiveness A Puissant, M Dufies, N Fenouille, I Ben Sahra, A Jacquel, G Robert, ... Journal of molecular cell biology 4 (4), 207-220, 2012 | 51 | 2012 |
Effects of proton versus photon irradiation on (lymph) angiogenic, inflammatory, proliferative and anti-tumor immune responses in head and neck squamous cell carcinoma M Lupu-Plesu, A Claren, S Martial, PD N'diaye, K Lebrigand, N Pons, ... Oncogenesis 6 (7), e354-e354, 2017 | 49 | 2017 |
All tyrosine kinase inhibitor-resistant chronic myelogenous cells are highly sensitive to ponatinib O Cassuto, M Dufies, A Jacquel, G Robert, C Ginet, A Dubois, A Hamouda, ... Oncotarget 3 (12), 1557, 2012 | 46 | 2012 |
Mechanism of action of the multikinase inhibitor Foretinib M Dufies, A Jacquel, G Robert, T Cluzeau, A Puissant, N Fenouille, ... Cell Cycle 10 (23), 4138-4148, 2011 | 45 | 2011 |
New CXCR1/CXCR2 inhibitors represent an effective treatment for kidney or head and neck cancers sensitive or refractory to reference treatments M Dufies, O Grytsai, C Ronco, O Camara, D Ambrosetti, A Hagege, ... Theranostics 9 (18), 5332, 2019 | 43 | 2019 |
In vitro and in vivo evaluation of fully substituted (5-(3-Ethoxy-3-oxopropynyl)-4-(ethoxycarbonyl)-1, 2, 3-triazolyl-glycosides as original nucleoside analogues to circumvent … H Amdouni, G Robert, M Driowya, N Furstoss, C Métier, A Dubois, ... Journal of Medicinal Chemistry 60 (4), 1523-1533, 2017 | 42 | 2017 |
Experimental models in neovascular age related macular degeneration O Rastoin, G Pagès, M Dufies International journal of molecular sciences 21 (13), 4627, 2020 | 38 | 2020 |
Azacitidine-resistant SKM1 myeloid cells are defective for AZA-induced mitochondrial apoptosis and autophagy T Cluzeau, G Robert, A Puissant, K Jean-Michel, JP Cassuto, S Raynaud, ... Cell Cycle 10 (14), 2339-2343, 2011 | 36 | 2011 |