Jonathan Y. Hsu
Jonathan Y. Hsu
Graduate Student
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CRISPResso2 provides accurate and rapid genome editing sequence analysis
K Clement, H Rees, MC Canver, JM Gehrke, R Farouni, JY Hsu, MA Cole, ...
Nature biotechnology 37 (3), 224-226, 2019
Engineered CRISPR–Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing
BP Kleinstiver, AA Sousa, RT Walton, YE Tak, JY Hsu, K Clement, ...
Nature biotechnology 37 (3), 276-282, 2019
Predictable and precise template-free CRISPR editing of pathogenic variants
MW Shen, M Arbab, JY Hsu, D Worstell, SJ Culbertson, O Krabbe, ...
Nature 563 (7733), 646-651, 2018
Nuclear RNA-seq of single neurons reveals molecular signatures of activation
B Lacar, SB Linker, BN Jaeger, SR Krishnaswami, JJ Barron, MJE Kelder, ...
Nature communications 7 (1), 11022, 2016
Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM
H Chen, L Albergante, JY Hsu, CA Lareau, G Lo Bosco, J Guan, S Zhou, ...
Nature communications 10 (1), 1903, 2019
A dual-deaminase CRISPR base editor enables concurrent adenine and cytosine editing
J Grünewald, R Zhou, CA Lareau, SP Garcia, S Iyer, BR Miller, ...
Nature biotechnology 38 (7), 861-864, 2020
Inducible and multiplex gene regulation using CRISPR–Cpf1-based transcription factors
YE Tak, BP Kleinstiver, JK Nuñez, JY Hsu, JE Horng, J Gong, ...
Nature methods 14 (12), 1163-1166, 2017
CRISPR prime editing with ribonucleoprotein complexes in zebrafish and primary human cells
K Petri, W Zhang, J Ma, A Schmidts, H Lee, JE Horng, DY Kim, IC Kurt, ...
Nature biotechnology 40 (2), 189-193, 2022
PrimeDesign software for rapid and simplified design of prime editing guide RNAs
JY Hsu, J Grünewald, R Szalay, J Shih, AV Anzalone, KC Lam, MW Shen, ...
Nature Communications 12 (1), 1034, 2021
Nup153 interacts with Sox2 to enable bimodal gene regulation and maintenance of neural progenitor cells
T Toda, JY Hsu, SB Linker, L Hu, ST Schafer, J Mertens, FV Jacinto, ...
Cell stem cell 21 (5), 618-634. e7, 2017
Transcription factor competition at the γ-globin promoters controls hemoglobin switching
N Liu, S Xu, Q Yao, Q Zhu, Y Kai, JY Hsu, P Sakon, L Pinello, GC Yuan, ...
Nature genetics 53 (4), 511-520, 2021
Response to “Unexpected mutations after CRISPR–Cas9 editing in vivo
CA Lareau, K Clement, JY Hsu, V Pattanayak, JK Joung, MJ Aryee, ...
Nature methods 15 (4), 238-239, 2018
Tuning gene activity by inducible and targeted regulation of gene expression in minimal bacterial cells
AM Mariscal, S Kakizawa, JY Hsu, K Tanaka, L González-González, ...
ACS synthetic biology 7 (6), 1538-1552, 2018
CRISPR-SURF: discovering regulatory elements by deconvolution of CRISPR tiling screen data
JY Hsu, CP Fulco, MA Cole, MC Canver, D Pellin, F Sher, R Farouni, ...
Nature methods 15 (12), 992-993, 2018
Technologies and computational analysis strategies for CRISPR applications
K Clement, JY Hsu, MC Canver, JK Joung, L Pinello
Molecular cell 79 (1), 11-29, 2020
Scalable characterization of the PAM requirements of CRISPR–Cas enzymes using HT-PAMDA
RT Walton, JY Hsu, JK Joung, BP Kleinstiver
Nature protocols 16 (3), 1511-1547, 2021
Room Temperature Isothermal Colorimetric Padlock Probe Rolling Circle Amplification for Viral DNA and RNA Detection
W Huang, J Ting, M Fang, H Hsu, J Su, T Misaki, D Chan, J Yang, TY Yeh, ...
BioRxiv, 2020.06. 12.128876, 2020
Accurate and rapid analysis of genome editing data from nucleases and base editors with CRISPResso2
K Clement, H Rees, MC Canver, JM Gehrke, R Farouni, JY Hsu, MA Cole, ...
Nature biotechnology 37 (3), 224, 2019
Human-specific regulation of neural maturation identified by cross-primate transcriptomics
SB Linker, I Narvaiza, JY Hsu, M Wang, F Qiu, APD Mendes, R Oefner, ...
Current Biology 32 (22), 4797-4807. e5, 2022
STREAM: single-cell trajectories reconstruction, exploration and mapping of omics data
H Chen, L Albergante, JY Hsu, CA Lareau, GL Bosco, J Guan, S Zhou, ...
bioRxiv, 302554, 2018
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