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Karl Werbovetz
Karl Werbovetz
Professor, Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University
Adresse e-mail validée de osu.edu
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Synthesis and Antiprotozoal Activity of Cationic 1,4-Diphenyl-1H-1,2,3-triazoles
SA Bakunov, SM Bakunova, T Wenzler, M Ghebru, KA Werbovetz, R Brun, ...
Journal of medicinal chemistry 53 (1), 254-272, 2010
2032010
Natural products from plants as drug candidates and lead compounds against leishmaniasis and trypanosomiasis
MM Salem, KA Werbovetz
Current medicinal chemistry 13 (21), 2571-2598, 2006
1932006
Diamidines as antitrypanosomal, antileishmanial and antimalarial agents.
K Werbovetz
Current opinion in investigational drugs (London, England: 2000) 7 (2), 147-157, 2006
1782006
Analysis of stereoelectronic properties, mechanism of action and pharmacophore of synthetic indolo [2, 1-b] quinazoline-6, 12-dione derivatives in relation to antileishmanial …
AK Bhattacharjee, DJ Skanchy, B Jennings, TH Hudson, JJ Brendle, ...
Bioorganic & medicinal chemistry 10 (6), 1979-1989, 2002
1562002
Novel amidines and analogues as promising agents against intracellular parasites: a systematic review
MNC Soeiro, K Werbovetz, DW Boykin, WD Wilson, MZ Wang, A Hemphill
Parasitology 140 (8), 929-951, 2013
1502013
Antikinetoplastid activity of 3-aryl-5-thiocyanatomethyl-1, 2, 4-oxadiazoles
DM Cottrell, J Capers, MM Salem, K DeLuca-Fradley, SL Croft, ...
Bioorganic & medicinal chemistry 12 (11), 2815-2824, 2004
1252004
Purification, characterization, and drug susceptibility of tubulin from Leishmania
KA Werbovetz, JJ Brendle, DL Sackett
Molecular and biochemical parasitology 98 (1), 53-65, 1999
1251999
Antileishmanial activities of several classes of aromatic dications
JJ Brendle, A Outlaw, A Kumar, DW Boykin, DA Patrick, RR Tidwell, ...
Antimicrobial agents and chemotherapy 46 (3), 797-807, 2002
1222002
Target-based drug discovery for malaria, leishmaniasis, and trypanosomiasis
KA Werbovetz
Current medicinal chemistry 7 (8), 835-860, 2000
1222000
Highly effective oral amphotericin B formulation against murine visceral leishmaniasis
KM Wasan, EK Wasan, P Gershkovich, X Zhu, RR Tidwell, KA Werbovetz, ...
Journal of Infectious Diseases 200 (3), 357-360, 2009
1092009
New antileishmanial candidates and lead compounds
JV Richard, KA Werbovetz
Current opinion in chemical biology 14 (4), 447-455, 2010
1032010
Novel arylimidamides for treatment of visceral leishmaniasis
MZ Wang, X Zhu, A Srivastava, Q Liu, JM Sweat, T Pandharkar, ...
Antimicrobial Agents and Chemotherapy 54 (6), 2507-2516, 2010
1012010
The activity of diguanidino and ‘reversed’diamidino 2, 5-diarylfurans versus Trypanosoma cruzi and Leishmania donovani
CE Stephens, R Brun, MM Salem, KA Werbovetz, F Tanious, WD Wilson, ...
Bioorganic & medicinal chemistry letters 13 (12), 2065-2069, 2003
1012003
Antitrypanosomal activity of 1, 2-dihydroquinolin-6-ols and their ester derivatives
J Fotie, M Kaiser, DA Delfín, J Manley, CS Reid, JM Paris, T Wenzler, ...
Journal of medicinal chemistry 53 (3), 966-982, 2010
982010
Isoflavonoids and Other Compounds from Psorothamnus arborescens with Antiprotozoal Activities
MM Salem, KA Werbovetz
Journal of natural products 69 (1), 43-49, 2006
962006
Antiprotozoal Compounds from Psorothamnus polydenius
MM Salem, KA Werbovetz
Journal of natural products 68 (1), 108-111, 2005
962005
Imidazoles as potential anticancer agents: an update on recent studies
P Sharma, C LaRosa, J Antwi, R Govindarajan, KA Werbovetz
Molecules 26 (14), 4213, 2021
882021
Antileishmanial Activity of a Series of N2,N4-Disubstituted Quinazoline-2,4-diamines
KS Van Horn, X Zhu, T Pandharkar, S Yang, B Vesely, M Vanaerschot, ...
Journal of medicinal chemistry 57 (12), 5141-5156, 2014
832014
Selective antimicrotubule activity of N1-phenyl-3, 5-dinitro-N4, N4-di-n-propylsulfanilamide (GB-II-5) against kinetoplastid parasites
KA Werbovetz, DL Sackett, D Delfín, G Bhattacharya, M Salem, T Obrzut, ...
Molecular Pharmacology 64 (6), 1325-1333, 2003
812003
Synthesis and in vitro antiprotozoal activity of bisbenzofuran cations
SM Bakunova, SA Bakunov, T Wenzler, T Barszcz, KA Werbovetz, R Brun, ...
Journal of medicinal chemistry 50 (23), 5807-5823, 2007
802007
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