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Douglas Ruden
Douglas Ruden
Professor of Obstetrics and Gynecology, Wayne State University
Adresse e-mail validée de wayne.edu - Page d'accueil
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A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w1118; iso …
P Cingolani, A Platts, LL Wang, M Coon, T Nguyen, L Wang, SJ Land, ...
fly 6 (2), 80-92, 2012
96572012
Using Drosophila melanogaster as a model for genotoxic chemical mutational studies with a new program, SnpSift
DM Ruden, P Cingolani, T Nguyen, SJ Land, X Lu
Frontiers in genetics 3, 24252, 2012
9412012
Ten putative contributors to the obesity epidemic
EJ McAllister, NV Dhurandhar, SW Keith, LJ Aronne, J Barger, M Baskin, ...
Critical reviews in food science and nutrition 49 (10), 868-913, 2009
9272009
Putative contributors to the secular increase in obesity: exploring the roads less traveled
SW Keith, DT Redden, PT Katzmarzyk, MM Boggiano, EC Hanlon, ...
International journal of obesity 30 (11), 1585-1594, 2006
8552006
Evidence for an epigenetic mechanism by which Hsp90 acts as a capacitor for morphological evolution
V Sollars, X Lu, L Xiao, X Wang, MD Garfinkel, DM Ruden
Nature genetics 33 (1), 70-74, 2003
4772003
Sequences required for in vitro transcriptional activation of a Drosophila hsp 70 gene
J Topol, DM Ruden, CS Parker
Cell 42 (2), 527-537, 1985
3121985
An examination of the association of selected toxic metals with total and central obesity indices: NHANES 99-02
MA Padilla, M Elobeid, DM Ruden, DB Allison
International journal of environmental research and public health 7 (9 …, 2010
2152010
Generating yeast transcriptional activators containing no yeast protein sequences
DM Ruden, J Ma, Y Li, K Wood, M Ptashne
Nature 350 (6315), 250-252, 1991
2091991
Identification of epigenetically altered genes in sporadic amyotrophic lateral sclerosis
C Figueroa-Romero, J Hur, DE Bender, CE Delaney, MD Cataldo, ...
PloS one 7 (12), e52672, 2012
1852012
Hypothesis: environmental regulation of 5-hydroxymethylcytosine by oxidative stress
N Chia, L Wang, X Lu, MC Senut, CA Brenner, DM Ruden
Epigenetics 6 (7), 853-856, 2011
1752011
Multigenerational epigenetic inheritance in humans: DNA methylation changes associated with maternal exposure to lead can be transmitted to the grandchildren
A Sen, N Heredia, MC Senut, S Land, K Hollocher, X Lu, MO Dereski, ...
Scientific reports 5 (1), 14466, 2015
1732015
Hsp90 and environmental impacts on epigenetic states: a model for the trans-generational effects of diethylstibesterol on uterine development and cancer
DM Ruden, L Xiao, MD Garfinkel, X Lu
Human molecular genetics 14 (suppl_1), R149-R155, 2005
1662005
CloudAligner: a fast and full-featured MapReduce based tool for sequence mapping
T Nguyen, W Shi, D Ruden
BMC research notes 4, 1-7, 2011
1622011
Radiation-induced epigenetic DNA methylation modification of radiation-response pathways
DA Antwih, KM Gabbara, WD Lancaster, DM Ruden, SP Zielske
Epigenetics 8 (8), 839-848, 2013
1502013
Hsp90 inhibitors and drug resistance in cancer: the potential benefits of combination therapies of Hsp90 inhibitors and other anti-cancer drugs
X Lu, L Xiao, L Wang, DM Ruden
Biochemical pharmacology 83 (8), 995-1004, 2012
1502012
Size‐dependent toxicity of gold nanoparticles on human embryonic stem cells and their neural derivatives
MC Senut, Y Zhang, F Liu, A Sen, DM Ruden, G Mao
Small 12 (5), 631-646, 2016
1442016
PKD2 cation channel is required for directional sperm movement and male fertility
Z Gao, DM Ruden, X Lu
Current Biology 13 (24), 2175-2178, 2003
1432003
Epigenetics of early-life lead exposure and effects on brain development
MC Senut, P Cingolani, A Sen, A Kruger, A Shaik, H Hirsch, ST Suhr, ...
Epigenomics 4 (6), 665-674, 2012
1362012
Endocrine disruptors and obesity: an examination of selected persistent organic pollutants in the NHANES 1999–2002 data
MA Elobeid, DW Brock, DB Allison, MA Padilla, DM Ruden
International journal of environmental research and public health 7 (7 …, 2010
1292010
Phthalate exposure and long-term epigenomic consequences: a review
S Dutta, DK Haggerty, DA Rappolee, DM Ruden
Frontiers in genetics 11, 499019, 2020
1272020
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