Hepatitis C virus (HCV) circulates as a population of different but closely related genomes: quasispecies nature of HCV genome distribution M Martell, JI Esteban, J Quer, J Genesca, A Weiner, R Esteban, J Guardia, ... Journal of virology 66 (5), 3225-3229, 1992 | 1283 | 1992 |
The changing epidemiology of hepatitis C virus infection in Europe JI Esteban, S Sauleda, J Quer Journal of hepatology 48 (1), 148-162, 2008 | 751 | 2008 |
Basic concepts in RNA virus evolution E Domingo, C Escarmís, N Sevilla, A Moya, SF Elena, J Quer, IS Novella, ... The FASEB Journal 10 (8), 859-864, 1996 | 594 | 1996 |
Transmission of hepatitis C virus by a cardiac surgeon JI Esteban, J Gómez, M Martell, B Cabot, J Quer, J Camps, A González, ... New England Journal of Medicine 334 (9), 555-561, 1996 | 522 | 1996 |
High-throughput real-time reverse transcription-PCR quantitation of hepatitis C virus RNA M Martell, J Gómez, JI Esteban, S Sauleda, J Quer, B Cabot, R Esteban, ... Journal of Clinical Microbiology 37 (2), 327-332, 1999 | 323 | 1999 |
The dynamic DNA methylomes of double-stranded DNA viruses associated with human cancer AF Fernandez, C Rosales, P Lopez-Nieva, O Graña, E Ballestar, ... Genome research 19 (3), 438-451, 2009 | 299 | 2009 |
Quantitative longitudinal evaluations of hepatitis delta virus RNA and hepatitis B virus DNA shows a dynamic, complex replicative profile in chronic hepatitis B and D M Schaper, F Rodriguez-Frias, R Jardi, D Tabernero, M Homs, G Ruiz, ... Journal of hepatology 52 (5), 658-664, 2010 | 196 | 2010 |
Viral quasispecies and the problem of vaccine-escape and drug-resistant mutants EJ Lien, A Das, P Nandy, S Ren, H Kleinkauf, H von Döhren, ... Progress in Drug Research/Fortschritte der Arzneimittelforschung/Progrès des …, 1997 | 138 | 1997 |
Extreme fitness differences in mammalian and insect hosts after continuous replication of vesicular stomatitis virus in sandfly cells IS Novella, DK Clarke, J Quer, EA Duarte, CH Lee, SC Weaver, SF Elena, ... Journal of virology 69 (11), 6805-6809, 1995 | 134 | 1995 |
Phylogenetic demonstration of hepatitis E infection transmitted by pork meat ingestion M Riveiro-Barciela, B Mínguez, R Gironés, F Rodriguez-Frías, J Quer, ... Journal of clinical gastroenterology 49 (2), 165-168, 2015 | 122 | 2015 |
Hepatitis C viral quasispecies J Gómez, M Martell, J Quer, B Cabot, JI Esteban Journal of viral hepatitis 6 (1), 3-16, 1999 | 119 | 1999 |
Dynamic behavior of hepatitis C virus quasispecies in patients undergoing orthotopic liver transplantation M Martell, JI Esteban, J Quer, V Vargas, R Esteban, J Guardia, J Gomez Journal of Virology 68 (5), 3425-3436, 1994 | 116 | 1994 |
Viral quasispecies complexity measures J Gregori, C Perales, F Rodriguez-Frias, JI Esteban, J Quer, E Domingo Virology 493, 227-237, 2016 | 111 | 2016 |
High-resolution hepatitis C virus subtyping using NS5B deep sequencing and phylogeny, an alternative to current methods J Quer, J Gregori, F Rodríguez-Frias, M Buti, A Madejon, ... Journal of clinical microbiology 53 (1), 219-226, 2015 | 106 | 2015 |
Exponential fitness gains of RNA virus populations are limited by bottleneck effects IS Novella, J Quer, E Domingo, JJ Holland Journal of Virology 73 (2), 1668-1671, 1999 | 106 | 1999 |
Reproducible nonlinear population dynamics and critical points during replicative competitions of RNA virus quasispecies J Quer, R Huerta, IS Novella, L Tsimring, E Domingo, JJ Holland Journal of molecular biology 264 (3), 465-471, 1996 | 94 | 1996 |
Naturally occurring NS3-protease-inhibitor resistant mutant A156T in the liver of an untreated chronic hepatitis C patient M Cubero, JI Esteban, T Otero, S Sauleda, M Bes, R Esteban, J Guardia, ... Virology 370 (2), 237-245, 2008 | 92 | 2008 |
T cell responses and viral variability in blood donation candidates with occult hepatitis B infection M Bes, V Vargas, M Piron, N Casamitjana, JI Esteban, N Vilanova, ... Journal of hepatology 56 (4), 765-774, 2012 | 89 | 2012 |
Red queen dynamics, competition and critical points in a model of RNA virus quasispecies RV Solé, R Ferrer, I González-Garcı́a, J Quer, E Domingo Journal of Theoretical Biology 198 (1), 47-59, 1999 | 87 | 1999 |
Response of hepatitis C virus to long-term passage in the presence of alpha interferon: multiple mutations and a common phenotype C Perales, NM Beach, I Gallego, ME Soria, J Quer, JI Esteban, C Rice, ... Journal of virology 87 (13), 7593-7607, 2013 | 83 | 2013 |