Lewis Cantley

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John AsaraAssociate Professor Medicine, Harvard Medical School; Director, Beth Israel Deaconess Medical CenterAdresse e-mail validée de bidmc.harvard.edu
Ji LuoNational Cancer InstituteAdresse e-mail validée de nih.gov
Costas LyssiotisAssistant Professor of Physiology, University of MichiganAdresse e-mail validée de lyssiotis.com
David FrumanProfessor of Molecular Biology & Biochemistry, UC IrvineAdresse e-mail validée de uci.edu
Alex TokerAdresse e-mail validée de bidmc.harvard.edu
Jason LocasaleDuke UniversityAdresse e-mail validée de alum.mit.edu
Lucia Rameh PlantVanderbilt UniversityAdresse e-mail validée de vanderbilt.edu
C. Ronald KahnJoslin Diabetes Center and Harvard Medical SchoolAdresse e-mail validée de joslin.harvard.edu
John BlenisProfessor of Pharmacology, Weill Cornell MedicineAdresse e-mail validée de med.cornell.edu
David R. KaplanHospital for Sick ChildrenAdresse e-mail validée de sickkids.ca
Steven ShoelsonHarvard Medical SchoolAdresse e-mail validée de joslin.harvard.edu
Reuben ShawThe Salk Institute of Biological StudiesAdresse e-mail validée de salk.edu
Pier Paolo PandolfiDirector, Cancer Center and Cancer Research Institute, Beth Israel Deaconess Medical CenterAdresse e-mail validée de bidmc.harvard.edu
Malcolm WhitmanHarvardAdresse e-mail validée de hms.harvard.edu
Kurt AugerGlaxoSmithKlineAdresse e-mail validée de gsk.com
Ronald A. DePinhoMD AndersonAdresse e-mail validée de mdanderson.org
Gerburg WulfAssociate Professor in Medicine, Harvard Medical SchoolAdresse e-mail validée de bidmc.harvard.edu
Benjamin E. TurkYale UniversityAdresse e-mail validée de yale.edu
Atsuo T. SasakiUniversity of Cincinnati, College of MedicineAdresse e-mail validée de uc.edu
George PoulogiannisThe Institute of Cancer Research, LondonAdresse e-mail validée de icr.ac.uk

Lewis Cantley

Weill Cornell Medical College

Adresse e-mail validée de med.cornell.edu

cancer metabolism signal transduction PI 3-Kinase Protein kinases


Titre Trier par citations Trier par année Trier par titre	Citée par Citée par	Année
Understanding the Warburg effect: the metabolic requirements of cell proliferation MG Vander Heiden, LC Cantley, CB Thompson science 324 (5930), 1029-1033, 2009	11382	2009
The phosphoinositide 3-kinase pathway LC Cantley Science 296 (5573), 1655-1657, 2002	6380	2002
AKT/PKB signaling: navigating downstream BD Manning, LC Cantley Cell 129 (7), 1261-1274, 2007	6077	2007
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling JA Engelman, K Zejnullahu, T Mitsudomi, Y Song, C Hyland, JO Park, ... science 316 (5827), 1039-1043, 2007	4706	2007
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate L Dang, DW White, S Gross, BD Bennett, MA Bittinger, EM Driggers, ... Nature 462 (7274), 739-744, 2009	3351	2009
Oncogenes and signal transduction LC Cantley, KR Auger, C Carpenter, B Duckworth, A Graziani, R Kapeller, ... Cell 64 (2), 281-302, 1991	3319	1991
SH2 domains recognize specific phosphopeptide sequences S Zhou, SE Shoelson, M Chaudhuri, G Gish, T Pawson, WG Haser, F King, ... Cell 72 (5), 767-778, 1993	3294	1993
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism JA Engelman, J Luo, LC Cantley Nature Reviews Genetics 7 (8), 606-619, 2006	3172	2006
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth HR Christofk, MG Vander Heiden, MH Harris, A Ramanathan, ... Nature 452 (7184), 230-233, 2008	2581	2008
New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway LC Cantley, BG Neel Proceedings of the National Academy of Sciences 96 (8), 4240-4245, 1999	2540	1999
Ras, PI (3) K and mTOR signalling controls tumour cell growth RJ Shaw, LC Cantley Nature 441 (7092), 424-430, 2006	2287	2006
PI3K: downstream AKTion blocks apoptosis TF Franke, DR Kaplan, LC Cantley Cell 88 (4), 435-437, 1997	1999	1997
The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin RJ Shaw, KA Lamia, D Vasquez, SH Koo, N Bardeesy, RA DePinho, ... Science 310 (5754), 1642-1646, 2005	1995	2005
PI3K pathway alterations in cancer: variations on a theme TL Yuan, LC Cantley Oncogene 27 (41), 5497-5510, 2008	1985	2008
Phosphoinositide kinases DA Fruman, RE Meyers, LC Cantley Annual review of biochemistry 67 (1), 481-507, 1998	1924	1998
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis GM DeNicola, FA Karreth, TJ Humpton, A Gopinathan, C Wei, K Frese, ... Nature 475 (7354), 106-109, 2011	1883*	2011
Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3, 4-bisphosphate TF Franke, DR Kaplan, LC Cantley, A Toker Science 275 (5300), 665-668, 1997	1802	1997
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress RJ Shaw, M Kosmatka, N Bardeesy, RL Hurley, LA Witters, RA DePinho, ... Proceedings of the National Academy of Sciences 101 (10), 3329-3335, 2004	1795	2004
Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs JC Obenauer, LC Cantley, MB Yaffe Nucleic acids research 31 (13), 3635-3641, 2003	1794	2003
The structural basis for 14-3-3: phosphopeptide binding specificity MB Yaffe, K Rittinger, S Volinia, PR Caron, A Aitken, H Leffers, ... Cell 91 (7), 961-971, 1997	1749	1997

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