Lewis Cantley
Lewis Cantley
Weill Cornell Medical College
Verified email at med.cornell.edu
Title
Cited by
Cited by
Year
Understanding the Warburg effect: the metabolic requirements of cell proliferation
MG Vander Heiden, LC Cantley, CB Thompson
science 324 (5930), 1029-1033, 2009
102292009
The phosphoinositide 3-kinase pathway
LC Cantley
Science 296 (5573), 1655-1657, 2002
61792002
AKT/PKB signaling: navigating downstream
BD Manning, LC Cantley
Cell 129 (7), 1261-1274, 2007
58022007
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
JA Engelman, K Zejnullahu, T Mitsudomi, Y Song, C Hyland, JO Park, ...
science 316 (5827), 1039-1043, 2007
45562007
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
L Dang, DW White, S Gross, BD Bennett, MA Bittinger, EM Driggers, ...
Nature 462 (7274), 739-744, 2009
31252009
SH2 domains recognize specific phosphopeptide sequences
S Zhou, SE Shoelson, M Chaudhuri, G Gish, T Pawson, WG Haser, F King, ...
Cell 72 (5), 767-778, 1993
31191993
Oncogenes and signal transduction
LC Cantley, KR Auger, C Carpenter, B Duckworth, A Graziani, R Kapeller, ...
Cell 64 (2), 281-302, 1991
30291991
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
JA Engelman, J Luo, LC Cantley
Nature Reviews Genetics 7 (8), 606-619, 2006
30022006
New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway
LC Cantley, BG Neel
Proceedings of the National Academy of Sciences 96 (8), 4240-4245, 1999
24911999
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
HR Christofk, MG Vander Heiden, MH Harris, A Ramanathan, ...
Nature 452 (7184), 230-233, 2008
24762008
Ras, PI (3) K and mTOR signalling controls tumour cell growth
RJ Shaw, LC Cantley
Nature 441 (7092), 424-430, 2006
22232006
PI3K: downstream AKTion blocks apoptosis
TF Franke, DR Kaplan, LC Cantley
Cell 88 (4), 435-437, 1997
19381997
The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin
RJ Shaw, KA Lamia, D Vasquez, SH Koo, N Bardeesy, RA DePinho, ...
Science 310 (5754), 1642-1646, 2005
19202005
PI3K pathway alterations in cancer: variations on a theme
TL Yuan, LC Cantley
Oncogene 27 (41), 5497-5510, 2008
19082008
Phosphoinositide kinases
DA Fruman, RE Meyers, LC Cantley
Annual review of biochemistry 67 (1), 481-507, 1998
18601998
Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs
JC Obenauer, LC Cantley, MB Yaffe
Nucleic acids research 31 (13), 3635-3641, 2003
17552003
Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3, 4-bisphosphate
TF Franke, DR Kaplan, LC Cantley, A Toker
Science 275 (5300), 665-668, 1997
17421997
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
RJ Shaw, M Kosmatka, N Bardeesy, RL Hurley, LA Witters, RA DePinho, ...
Proceedings of the National Academy of Sciences 101 (10), 3329-3335, 2004
17052004
The structural basis for 14-3-3: phosphopeptide binding specificity
MB Yaffe, K Rittinger, S Volinia, PR Caron, A Aitken, H Leffers, ...
Cell 91 (7), 961-971, 1997
17001997
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
GM DeNicola, FA Karreth, TJ Humpton, A Gopinathan, C Wei, K Frese, ...
Nature 475 (7354), 106-109, 2011
1684*2011
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