| Man-made cell-like compartments for molecular evolution DS Tawfik, AD Griffiths Nature biotechnology 16 (7), 652-656, 1998 | 1394 | 1998 |
| Kemp elimination catalysts by computational enzyme design D Röthlisberger, O Khersonsky, AM Wollacott, L Jiang, J DeChancie, ... Nature 453 (7192), 190-195, 2008 | 1366 | 2008 |
| Enzyme promiscuity: a mechanistic and evolutionary perspective OKDS Tawfik Annual review of biochemistry 79, 471-505, 2010 | 1243 | 2010 |
| The'evolvability'of promiscuous protein functions A Aharoni, L Gaidukov, O Khersonsky, SMQ Gould, C Roodveldt, ... Nature genetics 37 (1), 73-76, 2005 | 926 | 2005 |
| Protein dynamism and evolvability N Tokuriki, DS Tawfik Science 324 (5924), 203-207, 2009 | 840 | 2009 |
| The moderately efficient enzyme: evolutionary and physicochemical trends shaping enzyme parameters A Bar-Even, E Noor, Y Savir, W Liebermeister, D Davidi, DS Tawfik, ... Biochemistry 50 (21), 4402-4410, 2011 | 839 | 2011 |
| Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes M Harel, A Aharoni, L Gaidukov, B Brumshtein, O Khersonsky, R Meged, ... Nature structural & molecular biology 11 (5), 412-419, 2004 | 797 | 2004 |
| Antibody multispecificity mediated by conformational diversity LC James, P Roversi, DS Tawfik Science 299 (5611), 1362-1367, 2003 | 781 | 2003 |
| Stability effects of mutations and protein evolvability N Tokuriki, DS Tawfik Current opinion in structural biology 19 (5), 596-604, 2009 | 758 | 2009 |
| Enzyme promiscuity: evolutionary and mechanistic aspects O Khersonsky, C Roodveldt, DS Tawfik Current opinion in chemical biology 10 (5), 498-508, 2006 | 696 | 2006 |
| Conformational diversity and protein evolution–a 60-year-old hypothesis revisited LC James, DS Tawfik Trends in biochemical sciences 28 (7), 361-368, 2003 | 626 | 2003 |
| Miniaturising the laboratory in emulsion droplets AD Griffiths, DS Tawfik Trends in biotechnology 24 (9), 395-402, 2006 | 515 | 2006 |
| Amplification of complex gene libraries by emulsion PCR R Williams, SG Peisajovich, OJ Miller, S Magdassi, DS Tawfik, AD Griffiths Nature methods 3 (7), 545-550, 2006 | 510 | 2006 |
| How protein stability and new functions trade off N Tokuriki, F Stricher, L Serrano, DS Tawfik PLoS computational biology 4 (2), e1000002, 2008 | 507 | 2008 |
| Structure− reactivity studies of serum paraoxonase PON1 suggest that its native activity is lactonase O Khersonsky, DS Tawfik Biochemistry 44 (16), 6371-6382, 2005 | 493 | 2005 |
| In vitro sorting method A Griffiths, D Tawfik US Patent 7,638,276, 2009 | 473* | 2009 |
| Robustness–epistasis link shapes the fitness landscape of a randomly drifting protein S Bershtein, M Segal, R Bekerman, N Tokuriki, DS Tawfik Nature 444 (7121), 929-932, 2006 | 426 | 2006 |
| Directed evolution of an extremely fast phosphotriesterase by in vitro compartmentalization AD Griffiths, DS Tawfik The EMBO journal 22 (1), 24-35, 2003 | 412 | 2003 |
| Mutational effects and the evolution of new protein functions M Soskine, DS Tawfik Nature Reviews Genetics 11 (8), 572-582, 2010 | 396 | 2010 |
| The stability effects of protein mutations appear to be universally distributed N Tokuriki, F Stricher, J Schymkowitz, L Serrano, DS Tawfik Journal of molecular biology 369 (5), 1318-1332, 2007 | 381 | 2007 |
