| Okadaic acid: a new probe for the study of cellular regulation P Cohen, CFB Holmes, Y Tsukitani Trends in biochemical sciences 15 (3), 98-102, 1990 | 1758 | 1990 |
| Mannose 6-phosphate/insulin-like growth factor II receptor is a death receptor for granzyme B during cytotoxic T cell–induced apoptosis B Motyka, G Korbutt, MJ Pinkoski, JA Heibein, A Caputo, M Hobman, ... Cell 103 (3), 491-500, 2000 | 575 | 2000 |
| Adsorption of microcystin-LR by activated carbon and removal in full scale water treatment TW Lambert, CFB Holmes, SE Hrudey Water Research 30 (6), 1411-1422, 1996 | 297 | 1996 |
| Motuporin, a potent protein phosphatase inhibitor isolated from the Papua New Guinea sponge Theonella swinhoei Gray ED De Silva, DE Williams, RJ Andersen, H Klix, CFB Holmes, TM Allen Tetrahedron letters 33 (12), 1561-1564, 1992 | 288 | 1992 |
| Chemical and biological evidence links microcystins to salmon ‘netpen liver disease’ RJ Andersen, HA Luu, DZX Chen, CFB Holmes, ML Kent, M Le Blanc, ... Toxicon 31 (10), 1315-1323, 1993 | 272 | 1993 |
| A molecular basis for different interactions of marine toxins with protein phosphatase-1: molecular models for bound motuporin, microcystins, okadaic acid, and calyculin A JR Bagu, BD Sykes, MM Craig, CFB Holmes Journal of Biological Chemistry 272 (8), 5087-5097, 1997 | 228 | 1997 |
| Microcystin-LR concentration in aquatic food web compartments from lakes of varying trophic status BG Kotak, RW Zurawell, EE Prepas, CFB Holmes Canadian Journal of Fisheries and Aquatic Sciences 53 (9), 1974-1985, 1996 | 213 | 1996 |
| Molecular mechanisms underlying the interaction of motuporin and microcystins with type-1 and type-2A protein phosphatases M Craig, HA Luu, TL McCready, CFB Holmes, D Williams, RJ Andersen Biochemistry and cell biology 74 (4), 569-578, 1996 | 213 | 1996 |
| Crystal structure of the tumor-promoter okadaic acid bound to protein phosphatase-1 JT Maynes, KS Bateman, MM Cherney, AK Das, HA Luu, CFB Holmes, ... Journal of Biological Chemistry 276 (47), 44078-44082, 2001 | 210 | 2001 |
| The adsorption of microcystin-LR by natural clay particles RJ Morris, DE Williams, HA Luu, CFB Holmes, RJ Andersen, SE Calvert Toxicon 38 (2), 303-308, 2000 | 205 | 2000 |
| Bioaccumulation and clearance of microcystins from salt water mussels, Mytilus edulis, and in vivo evidence for covalently bound microcystins in mussel tissues DE Williams, SC Dawe, ML Kent, RJ Andersen, M Craig, CFB Holmes Toxicon 35 (11), 1617-1625, 1997 | 205 | 1997 |
| Regulation of matrix metalloproteinase‐2 (MMP‐2) activity by phosphorylation M Sariahmetoglu, BD Crawford, H Leon, J Sawicka, L Li, BJ Ballermann, ... The FASEB Journal 21 (10), 2486-2495, 2007 | 201 | 2007 |
| Evidence for a covalently bound form of microcystin-LR in salmon liver and dungeness crab larvae DE Williams, M Craig, SC Dawe, ML Kent, CFB Holmes, RJ Andersen Chemical Research in Toxicology 10 (4), 463-469, 1997 | 158 | 1997 |
| Accumulation and elimination of cyanobacterial hepatotoxins by the freshwater clam Anodonta grandis simpsoniana EE Prepas, BG Kotak, LM Campbell, JC Evans, SE Hrudey, CFB Holmes Canadian Journal of Fisheries and Aquatic Sciences 54 (1), 41-46, 1997 | 153 | 1997 |
| Molecular mechanisms underlying inhibition of protein phosphatases by marine toxins JF Dawson, CF Holmes Front. Biosci 4 (1), D646-D658, 1999 | 147 | 1999 |
| Analysis of the in vivo phosphorylation state of rabbit skeletal muscle glycogen synthase by fast‐atom‐bombardment mass spectrometry L Poulter, SG Ang, BW Gibson, DH Williams, CFB Holmes, FB Caudwell, ... European journal of biochemistry 175 (3), 497-510, 1988 | 131 | 1988 |
| Liquid chromatography-linked protein phosphatase bioassay; a highly sensitive marine bioscreen for okadaic acid and related diarrhetic shellfish toxins CFB Holmes Toxicon 29 (4-5), 469-477, 1991 | 128 | 1991 |
| Quantitation of the microcystin hepatotoxins in water at environmentally relevant concentrations with the protein phosphatase bioassay TW Lambert, MP Boland, CFB Holmes, SE Hrudey Environmental science & technology 28 (4), 753-755, 1994 | 127 | 1994 |
| [40] Protein phosphatase inhibitor-1 and inhibitor-2 from rabbit skeletal muscle P Cohen, JG Foulkes, CFB Holmes, GA Nimmo, NK Tonks Methods in enzymology 159, 427-437, 1988 | 126 | 1988 |
| Comparison of liquid chromatography/mass spectrometry, ELISA, and phosphatase assay for the determination of microcystins in blue-green algae products JF Lawrence, B Niedzwiadek, C Menard, BPY Lau, D Lewis, ... Journal of AOAC International 84 (4), 1035-1044, 2001 | 122 | 2001 |
