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Matthew Frieman
Matthew Frieman
Professor, University of Maryland School of Medicine
Adresse e-mail validée de som.umaryland.edu - Page d'accueil
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Phase 1–2 trial of a SARS-CoV-2 recombinant spike protein nanoparticle vaccine
C Keech, G Albert, I Cho, A Robertson, P Reed, S Neal, JS Plested, M Zhu, ...
New england journal of medicine 383 (24), 2320-2332, 2020
12652020
Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail
J Hansen, A Baum, KE Pascal, V Russo, S Giordano, E Wloga, BO Fulton, ...
Science 369 (6506), 1010-1014, 2020
9732020
Animal models for COVID-19
C Muñoz-Fontela, WE Dowling, SGP Funnell, PS Gsell, AX Riveros-Balta, ...
Nature 586 (7830), 509-515, 2020
7932020
Severe acute respiratory syndrome coronavirus open reading frame (ORF) 3b, ORF 6, and nucleocapsid proteins function as interferon antagonists
SA Kopecky-Bromberg, L Martínez-Sobrido, M Frieman, RA Baric, ...
Journal of virology 81 (2), 548-557, 2007
7452007
Repurposing of clinically developed drugs for treatment of Middle East respiratory syndrome coronavirus infection
J Dyall, CM Coleman, T Venkataraman, MR Holbrook, J Kindrachuk, ...
Antimicrobial agents and chemotherapy 58 (8), 4885-4893, 2014
7302014
Selective naked-eye detection of SARS-CoV-2 mediated by N gene targeted antisense oligonucleotide capped plasmonic nanoparticles
P Moitra, M Alafeef, K Dighe, MB Frieman, D Pan
ACS nano 14 (6), 7617-7627, 2020
6932020
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ...
Science 370 (6521), eabe9403, 2020
6082020
Severe acute respiratory syndrome coronavirus ORF6 antagonizes STAT1 function by sequestering nuclear import factors on the rough endoplasmic reticulum/Golgi membrane
M Frieman, B Yount, M Heise, SA Kopecky-Bromberg, P Palese, RS Baric
Journal of virology 81 (18), 9812-9824, 2007
5972007
Bats and coronaviruses
A Banerjee, K Kulcsar, V Misra, M Frieman, K Mossman
Viruses 11 (1), 41, 2019
5862019
Binding and neutralization antibody titers after a single vaccine dose in health care workers previously infected with SARS-CoV-2
S Saadat, ZR Tehrani, J Logue, M Newman, MB Frieman, AD Harris, ...
Jama 325 (14), 1467-1469, 2021
4252021
Severe acute respiratory syndrome coronavirus papain-like protease ubiquitin-like domain and catalytic domain regulate antagonism of IRF3 and NF-κB signaling
M Frieman, K Ratia, RE Johnston, AD Mesecar, RS Baric
Journal of virology 83 (13), 6689-6705, 2009
4042009
Antiviral potential of ERK/MAPK and PI3K/AKT/mTOR signaling modulation for Middle East respiratory syndrome coronavirus infection as identified by temporal kinome analysis
J Kindrachuk, B Ork, S Mazur, MR Holbrook, MB Frieman, D Traynor, ...
Antimicrobial agents and chemotherapy 59 (2), 1088-1099, 2015
4002015
SARS-CoV-2 spike glycoprotein vaccine candidate NVX-CoV2373 immunogenicity in baboons and protection in mice
JH Tian, N Patel, R Haupt, H Zhou, S Weston, H Hammond, J Logue, ...
Nature communications 12 (1), 372, 2021
3932021
Comorbid diabetes results in immune dysregulation and enhanced disease severity following MERS-CoV infection
KA Kulcsar, CM Coleman, SE Beck, MB Frieman
JCI insight 4 (20), 2019
3932019
Severe acute respiratory syndrome coronavirus evades antiviral signaling: role of nsp1 and rational design of an attenuated strain
MG Wathelet, M Orr, MB Frieman, RS Baric
Journal of virology 81 (21), 11620-11633, 2007
3832007
Evidence supporting a zoonotic origin of human coronavirus strain NL63
J Huynh, S Li, B Yount, A Smith, L Sturges, JC Olsen, J Nagel, ...
Journal of virology 86 (23), 12816-12825, 2012
3692012
Insights from nanomedicine into chloroquine efficacy against COVID-19
TY Hu, M Frieman, J Wolfram
Nature nanotechnology 15 (4), 247-249, 2020
3352020
Purified coronavirus spike protein nanoparticles induce coronavirus neutralizing antibodies in mice
CM Coleman, YV Liu, H Mu, JK Taylor, M Massare, DC Flyer, GM Glenn, ...
Vaccine 32 (26), 3169-3174, 2014
3302014
Severe acute respiratory syndrome coronavirus group-specific open reading frames encode nonessential functions for replication in cell cultures and mice
B Yount, RS Roberts, AC Sims, D Deming, MB Frieman, J Sparks, ...
Journal of virology 79 (23), 14909-14922, 2005
3122005
Abelson kinase inhibitors are potent inhibitors of severe acute respiratory syndrome coronavirus and Middle East respiratory syndrome coronavirus fusion
CM Coleman, JM Sisk, RM Mingo, EA Nelson, JM White, MB Frieman
Journal of virology 90 (19), 8924-8933, 2016
2892016
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