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Wilhelm Schwaeble
Wilhelm Schwaeble
Professor of Immunology
Adresse e-mail validée de cam.ac.uk
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A second serine protease associated with mannan-binding lectin that activates complement
S Thiel, T Vorup-Jensen, CM Stover, W Schwaeble, SB Laursen, ...
Nature 386 (6624), 506-510, 1997
10691997
De novo expression of intercellular-adhesion molecule 1 in melanoma correlates with increased risk of metastasis.
JP Johnson, BG Stade, B Holzmann, W Schwäble, G Riethmüller
Proceedings of the National Academy of Sciences 86 (2), 641-644, 1989
4791989
Biochemical and functional characterization of the interaction between pentraxin 3 and C1q
AJ Nauta, B Bottazzi, A Mantovani, G Salvatori, U Kishore, WJ Schwaeble, ...
European journal of immunology 33 (2), 465-473, 2003
4342003
Direct binding of C1q to apoptotic cells and cell blebs induces complement activation
AJ Nauta, LA Trouw, MR Daha, O Tijsma, R Nieuwland, WJ Schwaeble, ...
European journal of immunology 32 (6), 1726-1736, 2002
4102002
L-ficolin specifically binds to lipoteichoic acid, a cell wall constituent of Gram-positive bacteria, and activates the lectin pathway of complement
NJ Lynch, S Roscher, T Hartung, S Morath, M Matsushita, DN Maennel, ...
The Journal of Immunology 172 (2), 1198-1202, 2004
3472004
Natural substrates and inhibitors of mannan-binding lectin-associated serine protease-1 and-2: a study on recombinant catalytic fragments
G Ambrus, P Gál, M Kojima, K Szilágyi, J Balczer, J Antal, L Gráf, A Laich, ...
The Journal of Immunology 170 (3), 1374-1382, 2003
2942003
Two constituents of the initiation complex of the mannan-binding lectin activation pathway of complement are encoded by a single structural gene
CM Stover, S Thiel, M Thelen, NJ Lynch, T Vorup-Jensen, JC Jensenius, ...
The Journal of Immunology 162 (6), 3481-3490, 1999
2921999
Distinct pathways of mannan-binding lectin (MBL)-and C1-complex autoactivation revealed by reconstitution of MBL with recombinant MBL-associated serine protease-2
T Vorup-Jensen, SV Petersen, AG Hansen, K Poulsen, W Schwaeble, ...
The Journal of Immunology 165 (4), 2093-2100, 2000
2812000
Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury
WJ Schwaeble, NJ Lynch, JE Clark, M Marber, NJ Samani, YM Ali, ...
Proceedings of the National Academy of Sciences 108 (18), 7523-7528, 2011
2552011
Paths reunited: Initiation of the classical and lectin pathways of complement activation
R Wallis, DA Mitchell, R Schmid, WJ Schwaeble, AH Keeble
Immunobiology 215 (1), 1-11, 2010
2482010
The mannan-binding lectin-associated serine proteases (MASPs) and MAp19: four components of the lectin pathway activation complex encoded by two genes
W Schwaeble, MR Dahl, S Thiel, C Stover, JC Jensenius
Immunobiology 205 (4-5), 455-466, 2002
2262002
The lectin pathway of complement activation is a critical component of the innate immune response to pneumococcal infection
YM Ali, NJ Lynch, KS Haleem, T Fujita, Y Endo, S Hansen, U Holmskov, ...
PLoS pathogens 8 (7), e1002793, 2012
2092012
Complement C1q is dramatically up-regulated in brain microglia in response to transient global cerebral ischemia
MKH Schäfer, WJ Schwaeble, C Post, P Salvati, M Calabresi, RB Sim, ...
The Journal of Immunology 164 (10), 5446-5452, 2000
1942000
Interaction of C1q and mannan-binding lectin (MBL) with C1r, C1s, MBL-associated serine proteases 1 and 2, and the MBL-associated protein MAp19
S Thiel, SV Petersen, T Vorup-Jensen, M Matsushita, T Fujita, CM Stover, ...
The Journal of Immunology 165 (2), 878-887, 2000
1922000
Properdin, a positive regulator of complement activation, is released from secondary granules of stimulated peripheral blood neutrophils.
U Wirthmueller, B Dewald, M Thelen, MK Schäfer, C Stover, K Whaley, ...
Journal of immunology (Baltimore, Md.: 1950) 158 (9), 4444-4451, 1997
1881997
Activation of mannan‐binding lectin‐associated serine proteases leads to generation of a fibrin clot
KC Gulla, K Gupta, A Krarup, P Gal, WJ Schwaeble, RB Sim, ...
Immunology 129 (4), 482-495, 2010
1782010
The classical activation pathway of the human complement system is specifically inhibited by calreticulin from Trypanosoma cruzi
V Ferreira, C Valck, G Sánchez, A Gingras, S Tzima, MC Molina, R Sim, ...
The Journal of Immunology 172 (5), 3042-3050, 2004
1752004
The complement system in ischemia–reperfusion injuries
WB Gorsuch, E Chrysanthou, WJ Schwaeble, GL Stahl
Immunobiology 217 (11), 1026-1033, 2012
1702012
Ficolins: novel pattern recognition molecules of the innate immune response
VL Runza, W Schwaeble, DN Männel
Immunobiology 213 (3-4), 297-306, 2008
1702008
Does properdin crosslink the cellular and the humoral immune response?
WJ Schwaeble, KBM Reid
Immunology today 20 (1), 17-21, 1999
1581999
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