Nasal chemosensory cells use bitter taste signaling to detect irritants and bacterial signals M Tizzano, BD Gulbransen, A Vandenbeuch, TR Clapp, JP Herman, ... Proceedings of the National Academy of Sciences 107 (7), 3210-3215, 2010 | 447 | 2010 |
Allosteric activation of functionally asymmetric RAF kinase dimers J Hu, EC Stites, H Yu, EA Germino, HS Meharena, PJS Stork, AP Kornev, ... Cell 154 (5), 1036-1046, 2013 | 305 | 2013 |
Deciphering the structural basis of eukaryotic protein kinase regulation HS Meharena, P Chang, MM Keshwani, K Oruganty, AK Nene, N Kannan, ... PLoS biology 11 (10), e1001680, 2013 | 214 | 2013 |
Kinase regulation by hydrophobic spine assembly in cancer J Hu, LG Ahuja, HS Meharena, N Kannan, AP Kornev, SS Taylor, ... Molecular and cellular biology 35 (1), 264-276, 2015 | 106 | 2015 |
Mapping the epigenomic and transcriptomic interplay during memory formation and recall in the hippocampal engram ensemble A Marco, HS Meharena, V Dileep, RM Raju, J Davila-Velderrain, ... Nature neuroscience 23 (12), 1606-1617, 2020 | 105 | 2020 |
A complex LuxR–LuxI type quorum sensing network in a roseobacterial marine sponge symbiont activates flagellar motility and inhibits biofilm formation J Zan, EM Cicirelli, NM Mohamed, H Sibhatu, S Kroll, O Choi, CL Uhlson, ... Molecular microbiology 85 (5), 916-933, 2012 | 95 | 2012 |
Lipid accumulation induced by APOE4 impairs microglial surveillance of neuronal-network activity MB Victor, N Leary, X Luna, HS Meharena, AN Scannail, PL Bozzelli, ... Cell Stem Cell 29 (8), 1197-1212. e8, 2022 | 90 | 2022 |
Pseudokinases from a structural perspective SS Taylor, A Shaw, J Hu, HS Meharena, A Kornev Biochemical Society Transactions 41 (4), 981-986, 2013 | 51 | 2013 |
Down-syndrome-induced senescence disrupts the nuclear architecture of neural progenitors HS Meharena, A Marco, V Dileep, ER Lockshin, GY Akatsu, J Mullahoo, ... Cell Stem Cell 29 (1), 116-130. e7, 2022 | 45 | 2022 |
Exploring the electron transfer properties of neuronal nitric-oxide synthase by reversal of the FMN redox potential H Li, A Das, H Sibhatu, J Jamal, SG Sligar, TL Poulos Journal of biological chemistry 283 (50), 34762-34772, 2008 | 42 | 2008 |
Evolution of a dynamic molecular switch SS Taylor, HS Meharena, AP Kornev IUBMB life 71 (6), 672-684, 2019 | 38 | 2019 |
Decoding the interactions regulating the active state mechanics of eukaryotic protein kinases HS Meharena, X Fan, LG Ahuja, MM Keshwani, CL McClendon, AM Chen, ... PLoS Biology 14 (11), e2000127, 2016 | 38 | 2016 |
Beta-Lactamase Repressor BlaI Modulates Staphylococcus aureus Cathelicidin Antimicrobial Peptide Resistance and Virulence MA Pence, NM Haste, HS Meharena, J Olson, RL Gallo, V Nizet, ... PloS one 10 (8), e0136605, 2015 | 38 | 2015 |
Neuronal DNA double-strand breaks lead to genome structural variations and 3D genome disruption in neurodegeneration V Dileep, CA Boix, H Mathys, A Marco, GM Welch, HS Meharena, A Loon, ... Cell 186 (20), 4404-4421. e20, 2023 | 33 | 2023 |
A solo luxI-type gene directs acylhomoserine lactone synthesis and contributes to motility control in the marine sponge symbiont Ruegeria sp. KLH11 J Zan, O Choi, H Meharena, CL Uhlson, MEA Churchill, RT Hill, C Fuqua Microbiology 161 (1), 50-56, 2015 | 22 | 2015 |
Defining the structure and function of acyl-homoserine lactone autoinducers MEA Churchill, HM Sibhatu, CL Uhlson Quorum Sensing: Methods and Protocols, 159-171, 2011 | 21 | 2011 |
From neurodevelopment to neurodegeneration: utilizing human stem cell models to gain insight into Down syndrome LA Watson, HS Meharena Frontiers in Genetics 14, 1198129, 2023 | 1 | 2023 |
Understanding redox regulation in membrane associated cytochrome P450s and the FMN domain of nitric oxide synthase A Das, H Li, Y Grinkova, H Sibhatu, J Jamal, TL Poulos, SG Sligar Chemical Research in Toxicology 23, 268-269, 2010 | 1 | 2010 |
Disruption of 3D-genome organization in neurodegeneration V Dileep, A Marco, GM Welch, HS Meharena, LH Tsai 2021 Alzheimer's Association International Conference, 2021 | | 2021 |
Evolution of a dynamic molecular switch. AP Kornev, SS Taylor, HS Meharena IUBMB Life 71 (6), 2019 | | 2019 |