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Pieter Beerepoot
Pieter Beerepoot
Fog Pharma
Adresse e-mail validée de fogpharma.com - Page d'accueil
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Tau PTM profiles identify patient heterogeneity and stages of Alzheimer’s disease
H Wesseling, W Mair, M Kumar, CN Schlaffner, S Tang, P Beerepoot, ...
Cell 183 (6), 1699-1713. e13, 2020
4132020
Tau molecular diversity contributes to clinical heterogeneity in Alzheimer’s disease
S Dujardin, C Commins, A Lathuiliere, P Beerepoot, AR Fernandes, ...
Nature medicine 26 (8), 1256-1263, 2020
3152020
Pharmacological chaperones of the dopamine transporter rescue dopamine transporter deficiency syndrome mutations in heterologous cells
P Beerepoot, VM Lam, A Salahpour
Journal of Biological Chemistry 291 (42), 22053-22062, 2016
432016
Pharmacological chaperone approaches for rescuing GPCR mutants: Current state, challenges, and screening strategies
P Beerepoot, R Nazari, A Salahpour
Pharmacological research 117, 242-251, 2017
312017
A novel assay for measurement of membrane‐protein surface expression using a β‐lactamase reporter
VM Lam, P Beerepoot, S Angers, A Salahpour
Traffic 14 (7), 778-784, 2013
302013
Sustained N‐methyl‐d‐aspartate receptor hypofunction remodels the dopamine system and impairs phasic signaling
MJ Ferris, M Milenkovic, S Liu, CA Mielnik, P Beerepoot, CE John, ...
European Journal of Neuroscience 40 (1), 2255-2263, 2014
252014
Effects of salvinorin A on locomotor sensitization to D2/D3 dopamine agonist quinpirole
P Beerepoot, V Lam, A Luu, B Tsoi, D Siebert, H Szechtman
Neuroscience letters 446 (2-3), 101-104, 2008
202008
N-terminal tagging of the dopamine transporter impairs protein expression and trafficking in vivo
LM Vecchio, MK Bermejo, P Beerepoot, AJ Ramsey, A Salahpour
Molecular and Cellular Neuroscience 61, 123-132, 2014
152014
Measurement of G protein-coupled receptor surface expression
P Beerepoot, VM Lam, A Salahpour
Journal of Receptors and Signal Transduction 33 (3), 162-165, 2013
102013
Author Correction: Tau molecular diversity contributes to clinical heterogeneity in Alzheimer’s disease
S Dujardin, C Commins, A Lathuiliere, P Beerepoot, AR Fernandes, ...
Nature medicine 27 (2), 356-356, 2021
92021
Behavioral effects of a potential novel TAAR1 antagonist
VM Lam, CA Mielnik, C Baimel, P Beerepoot, S Espinoza, I Sukhanov, ...
Frontiers in pharmacology 9, 953, 2018
92018
Structure-activity relationships of dopamine transporter pharmacological chaperones
C Sutton, EQ Williams, H Homsi, P Beerepoot, R Nazari, D Han, ...
Frontiers in Cellular Neuroscience 16, 832536, 2022
62022
A β-lactamase based assay to measure surface expression of membrane proteins
P Beerepoot, VM Lam, A Salahpour
Membrane Trafficking: Second Edition, 107-114, 2015
42015
Alzheimer proteopathic tau seeds are biochemically a forme fruste of mature paired helical filaments
M Kumar, N Quittot, S Dujardin, CN Schlaffner, A Viode, A Wiedmer, ...
Brain 147 (2), 637-648, 2024
12024
Discovery of a HeliconTM peptide inhibitor of the beta-catenin-TCF interaction with in vivo activity
BH White, Y Si, S Cappucci, Z Li, JD Ramirez, CM Ponthier, E Visness, ...
Cancer Research 83 (7_Supplement), 3094-3094, 2023
2023
Anti-tumor activity of Helicon inhibitors of Β-catenin-TCF interaction in patient-derived xenograft models
YG Si, M Choi, X Han, B White, Z Wu, E Visness, P Beerepoot, E Jaensch, ...
Cancer Research 83 (7_Supplement), 4972-4972, 2023
2023
Development of a novel and direct peptide Helicon࣪ inhibitor of β-catenin-TCF interaction with in vivo validation of transcriptional modulation and anti-tumor activity
Y Si, B White, S Cappucci, J Ramirez, C Ponthier, E Visness, K Ling, P Du, ...
Cancer Research 82 (12_Supplement), 345-345, 2022
2022
O5‐04‐04: ACCUMULATION OF MODIFICATIONS IN THE TAU CORE REGION DURING THE TAU AGGREGATION PROCESS IN ALZHEIMER'S DISEASE
P Beerepoot, H Wesseling, W Mair, M Svrdlikova, L Cheng, H Steen, ...
Alzheimer's & Dementia 15, P1623-P1624, 2019
2019
Pharmacological Chaperones of the Dopamine Transporter: A Strategy for Increasing Function of Wild Type and Mutant Transporter
PC Beerepoot
University of Toronto (Canada), 2017
2017
Pharmacological chaperones of the dopamine transporter
P Beerepoot, VM Lam, A Salahpour
2016
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