Mechanisms of stem cell self-renewal HE Shenghui, D Nakada, SJ Morrison Annual Review of Cell and Developmental 25, 377-406, 2009 | 778 | 2009 |
Energy-stress-mediated AMPK activation inhibits ferroptosis H Lee, F Zandkarimi, Y Zhang, JK Meena, J Kim, L Zhuang, S Tyagi, L Ma, ... Nature cell biology 22 (2), 225-234, 2020 | 669 | 2020 |
Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells D Nakada, TL Saunders, SJ Morrison Nature 468 (7324), 653-658, 2010 | 552 | 2010 |
Oestrogen increases haematopoietic stem-cell self-renewal in females and during pregnancy D Nakada, H Oguro, BP Levi, N Ryan, A Kitano, Y Saitoh, M Takeichi, ... Nature 505 (7484), 555-558, 2014 | 391 | 2014 |
ATM-related Tel1 associates with double-strand breaks through an Xrs2-dependent mechanism D Nakada, K Matsumoto, K Sugimoto Genes & development 17 (16), 1957-1962, 2003 | 391 | 2003 |
Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics K Morita, F Wang, K Jahn, T Hu, T Tanaka, Y Sasaki, J Kuipers, S Loghavi, ... Nature communications 11 (1), 5327, 2020 | 280 | 2020 |
Highly efficient genome editing of murine and human hematopoietic progenitor cells by CRISPR/Cas9 MC Gundry, L Brunetti, A Lin, AE Mayle, A Kitano, D Wagner, JI Hsu, ... Cell reports 17 (5), 1453-1461, 2016 | 277 | 2016 |
AMPK protects leukemia-initiating cells in myeloid leukemias from metabolic stress in the bone marrow Y Saito, RH Chapple, A Lin, A Kitano, D Nakada Cell stem cell 17 (5), 585-596, 2015 | 246 | 2015 |
Inhibition of AMPK catabolic action by GSK3 T Suzuki, D Bridges, D Nakada, G Skiniotis, SJ Morrison, JD Lin, ... Molecular cell 50 (3), 407-419, 2013 | 244 | 2013 |
mTOR activation induces tumor suppressors that inhibit leukemogenesis and deplete hematopoietic stem cells after Pten deletion JY Lee, D Nakada, OH Yilmaz, Z Tothova, NM Joseph, MS Lim, ... Cell stem cell 7 (5), 593-605, 2010 | 219 | 2010 |
Temporal changes in PTEN and mTORC2 regulation of hematopoietic stem cell self-renewal and leukemia suppression JA Magee, T Ikenoue, D Nakada, JY Lee, KL Guan, SJ Morrison Cell stem cell 11 (3), 415-428, 2012 | 201 | 2012 |
Prospective identification of functionally distinct stem cells and neurosphere-initiating cells in adult mouse forebrain JK Mich, RAJ Signer, D Nakada, A Pineda, RJ Burgess, TY Vue, ... elife 3, e02669, 2014 | 169 | 2014 |
Requirement of the Mre11 complex and exonuclease 1 for activation of the Mec1 signaling pathway D Nakada, Y Hirano, K Sugimoto Molecular and cellular biology 24 (22), 10016-10025, 2004 | 150 | 2004 |
Chl12 (Ctf18) forms a novel replication factor C-related complex and functions redundantly with Rad24 in the DNA replication checkpoint pathway T Naiki, T Kondo, D Nakada, K Matsumoto, K Sugimoto Molecular and cellular biology 21 (17), 5838-5845, 2001 | 128 | 2001 |
Clamp and clamp loader structures of the human checkpoint protein complexes, Rad9‐1‐1 and Rad17‐RFC Y Shiomi, A Shinozaki, D Nakada, K Sugimoto, J Usukura, C Obuse, ... Genes to Cells 7 (8), 861-868, 2002 | 116 | 2002 |
Integrating physiological regulation with stem cell and tissue homeostasis D Nakada, BP Levi, SJ Morrison Neuron 70 (4), 703-718, 2011 | 98 | 2011 |
Lineage tracing of murine adult hematopoietic stem cells reveals active contribution to steady-state hematopoiesis RH Chapple, YJ Tseng, T Hu, A Kitano, M Takeichi, KA Hoegenauer, ... Blood advances 2 (11), 1220-1228, 2018 | 87 | 2018 |
The ATM‐related Tel1 protein of Saccharomyces cerevisiae controls a checkpoint response following phleomycin treatment D Nakada, T Shimomura, K Matsumoto, K Sugimoto Nucleic acids research 31 (6), 1715-1724, 2003 | 81 | 2003 |
Association of Rad9 with double-strand breaks through a Mec1-dependent mechanism T Naiki, T Wakayama, D Nakada, K Matsumoto, K Sugimoto Molecular and cellular biology 24 (8), 3277-3285, 2004 | 80 | 2004 |
Role of the C terminus of Mec1 checkpoint kinase in its localization to sites of DNA damage D Nakada, Y Hirano, Y Tanaka, K Sugimoto Molecular biology of the cell 16 (11), 5227-5235, 2005 | 70 | 2005 |