Suivre
Malliga Iyer
Malliga Iyer
Investigator, NIH
Adresse e-mail validée de nih.gov
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Année
Crystal structure of the human cannabinoid receptor CB2
X Li, T Hua, K Vemuri, JH Ho, Y Wu, L Wu, P Popov, O Benchama, ...
Cell 176 (3), 459-467. e13, 2019
3442019
The therapeutic potential of second and third generation CB1R antagonists
R Cinar, MR Iyer, G Kunos
Pharmacology & therapeutics 208, 107477, 2020
1042020
Antagonism of sigma-1 receptors blocks compulsive-like eating
P Cottone, X Wang, JW Park, M Valenza, A Blasio, J Kwak, MR Iyer, ...
Neuropsychopharmacology 37 (12), 2593-2604, 2012
942012
The σ-receptor antagonist BD-1063 decreases ethanol intake and reinforcement in animal models of excessive drinking
V Sabino, P Cottone, Y Zhao, MR Iyer, L Steardo, KC Rice, B Conti, ...
Neuropsychopharmacology 34 (6), 1482-1493, 2009
942009
Liposomes containing monophosphoryl lipid A: a potent adjuvant system for inducing antibodies to heroin hapten analogs
GR Matyas, AV Mayorov, KC Rice, AE Jacobson, K Cheng, MR Iyer, F Li, ...
Vaccine 31 (26), 2804-2810, 2013
872013
Hybrid inhibitor of peripheral cannabinoid-1 receptors and inducible nitric oxide synthase mitigates liver fibrosis
R Cinar, MR Iyer, Z Liu, Z Cao, T Jourdan, K Erdelyi, G Godlewski, ...
JCI insight 1 (11), 2016
722016
Cannabinoid CB1 receptor overactivity contributes to the pathogenesis of idiopathic pulmonary fibrosis
R Cinar, BR Gochuico, MR Iyer, T Jourdan, T Yokoyama, JK Park, ...
JCI insight 2 (8), 2017
662017
Activation of σ-receptors induces binge-like drinking in Sardinian alcohol-preferring rats
V Sabino, P Cottone, A Blasio, MR Iyer, L Steardo, KC Rice, B Conti, ...
Neuropsychopharmacology 36 (6), 1207-1218, 2011
642011
Facial recognition of heroin vaccine opiates: type 1 cross-reactivities of antibodies induced by hydrolytically stable haptenic surrogates of heroin, 6-acetylmorphine, and morphine
GR Matyas, KC Rice, K Cheng, F Li, JFG Antoline, MR Iyer, AE Jacobson, ...
Vaccine 32 (13), 1473-1479, 2014
582014
Allenyl azide cycloaddition chemistry. synthesis of pyrrolidine-containing bicycles and tricycles via the possible intermediacy of azatrimethylenemethane species
KS Feldman, MR Iyer
Journal of the American Chemical Society 127 (13), 4590-4591, 2005
512005
Dual inhibition of cannabinoid CB1 receptor and inducible NOS attenuates obesity‐induced chronic kidney disease
S Udi, L Hinden, M Ahmad, A Drori, MR Iyer, R Cinar, ...
British journal of pharmacology 177 (1), 110-127, 2020
502020
Characterization and optimization of heroin hapten-BSA conjugates: method development for the synthesis of reproducible hapten-based vaccines
OB Torres, R Jalah, KC Rice, F Li, JFG Antoline, MR Iyer, AE Jacobson, ...
Analytical and Bioanalytical Chemistry 406, 5927-5937, 2014
502014
Allenyl azide cycloaddition chemistry. Synthesis of annelated indoles from 2-(allenyl) phenyl azide substrates
KS Feldman, MR Iyer, DK Hester
Organic letters 8 (14), 3113-3116, 2006
492006
Targeting peripheral CB1 receptors reduces ethanol intake via a gut-brain axis
G Godlewski, R Cinar, NJ Coffey, J Liu, T Jourdan, B Mukhopadhyay, ...
Cell metabolism 29 (6), 1320-1333. e8, 2019
422019
Cocaine reward is reduced by decreased expression of receptor-type protein tyrosine phosphatase D (PTPRD) and by a novel PTPRD antagonist
GR Uhl, MJ Martinez, P Paik, A Sulima, GH Bi, MR Iyer, E Gardner, ...
Proceedings of the National Academy of Sciences 115 (45), 11597-11602, 2018
402018
Sigma-1 receptor mediates acquisition of alcohol drinking and seeking behavior in alcohol-preferring rats
A Blasio, M Valenza, MR Iyer, KC Rice, L Steardo, T Hayashi, P Cottone, ...
Behavioural brain research 287, 315-322, 2015
372015
Allenyl azide cycloaddition chemistry. 2, 3-cyclopentennelated indole synthesis through indolidene intermediates
KS Feldman, DK Hester, MR Iyer, PJ Munson, C Silva Lopez, ON Faza
The Journal of organic chemistry 74 (14), 4958-4974, 2009
372009
Design, Synthesis, and Biological Evaluation of Novel, Non-Brain-Penetrant, Hybrid Cannabinoid CB1R Inverse Agonist/Inducible Nitric Oxide Synthase (iNOS …
MR Iyer, R Cinar, A Katz, M Gao, K Erdelyi, T Jourdan, NJ Coffey, ...
Journal of Medicinal Chemistry 60 (3), 1126-1141, 2017
362017
Synthesis and immunological effects of heroin vaccines
F Li, K Cheng, JFG Antoline, MR Iyer, GR Matyas, OB Torres, R Jalah, ...
Organic & biomolecular chemistry 12 (37), 7211-7232, 2014
342014
Cyclization cascade of allenyl azides: a dual mechanism
CS López, ON Faza, KS Feldman, MR Iyer, DK Hester
Journal of the American Chemical Society 129 (24), 7638-7646, 2007
342007
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