Linkage disequilibrium mapping identifies a 390 kb region associated with CYP2D6 poor drug metabolising activity LK Hosking, PR Boyd, CF Xu, M Nissum, K Cantone, IJ Purvis, R Khakhar, ... The Pharmacogenomics Journal 2 (3), 165-175, 2002 | 4966 | 2002 |
A novel, rapid method for the isolation of terminal sequences from yeast artificial chromosome (YAC) clones J Riley, R Butler, D Ogilvie, R Finniear, D Jenner, S Powell, R Anand, ... Nucleic acids research 18 (10), 2887-2890, 1990 | 856 | 1990 |
Detection of genotyping errors by Hardy–Weinberg equilibrium testing L Hosking, S Lumsden, K Lewis, A Yeo, L McCarthy, A Bansal, J Riley, ... European Journal of Human Genetics 12 (5), 395-399, 2004 | 495 | 2004 |
SNPing away at complex diseases: analysis of single-nucleotide polymorphisms around APOE in Alzheimer disease ER Martin, EH Lai, JR Gilbert, AR Rogala, AJ Afshari, J Riley, KL Finch, ... The American Journal of Human Genetics 67 (2), 383-394, 2000 | 468 | 2000 |
Structure and physical map of 64 variable segments in the 3′ 0.8–megabase region of the human immunoglobulin heavy–chain locus F Matsuda, E Kyun Shin, H Nagaoka, R Matsumura, M Haino, Y Fukita, ... Nature genetics 3 (1), 88-94, 1993 | 392 | 1993 |
INPP5E mutations cause primary cilium signaling defects, ciliary instability and ciliopathies in human and mouse M Jacoby, JJ Cox, S Gayral, DJ Hampshire, M Ayub, M Blockmans, ... Nature genetics 41 (9), 1027-1031, 2009 | 366 | 2009 |
A 3.5 genome equivalent multi access YAC library: construction, characterisation, screening and storage R Anand, JH Riley, R Butler, JC Smith, AF Markham Nucleic acids research 18 (8), 1951-1956, 1990 | 316 | 1990 |
U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics D Lefaudeux, B De Meulder, MJ Loza, N Peffer, A Rowe, F Baribaud, ... Journal of Allergy and Clinical Immunology 139 (6), 1797-1807, 2017 | 292 | 2017 |
Reported pneumonia in patients with COPD: findings from the INSPIRE study PMA Calverley, RA Stockley, TAR Seemungal, G Hagan, LR Willits, ... Chest 139 (3), 505-512, 2011 | 237 | 2011 |
A 4-Mb high-density single nucleotide polymorphism-based map around human APOE E Lai, J Riley, I Purvis, A Roses Genomics 54 (1), 31-38, 1998 | 230 | 1998 |
Lessons from ECLIPSE: a review of COPD biomarkers R Faner, R Tal-Singer, JH Riley, B Celli, J Vestbo, W MacNee, P Bakke, ... Thorax 69 (7), 666-672, 2014 | 196 | 2014 |
Psoriasis susceptibility locus in chromosome region 3q21 identified in patients from southwest Sweden F Enlund, L Samuelsson, C Enerbäck, A Inerot, J Wahlström, M Yhr, ... European journal of human genetics 7 (7), 783-790, 1999 | 189 | 1999 |
Single-nucleotide polymorphism alleles in the insulin receptor gene are associated with typical migraine LC McCarthy, DA Hosford, JH Riley, MI Bird, NJ White, DR Hewett, ... Genomics 78 (3), 135-149, 2001 | 175 | 2001 |
Metabolic profiling detects biomarkers of protein degradation in COPD patients BK Ubhi, JH Riley, PA Shaw, DA Lomas, R Tal-Singer, W MacNee, ... European Respiratory Journal 40 (2), 345-355, 2012 | 170 | 2012 |
Expression of the human calcitonin/CGRP gene in lung and thyroid carcinoma. MR Edbrooke, D Parker, JH McVey, JH Riley, GD Sorenson, OS Pettengill, ... The EMBO Journal 4 (3), 715-724, 1985 | 167 | 1985 |
Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease DK Kim, MH Cho, CP Hersh, DA Lomas, BE Miller, X Kong, P Bakke, ... American journal of respiratory and critical care medicine 186 (12), 1238-1247, 2012 | 157 | 2012 |
Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation Z Jevnikar, J Östling, E Ax, J Calvén, K Thörn, E Israelsson, L Öberg, ... Journal of allergy and clinical immunology 143 (2), 577-590, 2019 | 155 | 2019 |
Identification of a psoriasis susceptibility candidate gene by linkage disequilibrium mapping with a localized single nucleotide polymorphism map D Hewett, L Samuelsson, J Polding, F Enlund, D Smart, K Cantone, ... Genomics 79 (3), 305-314, 2002 | 144 | 2002 |
Isolation of cDNA clones using yeast artificial chromosome probes P Elvin, G Slynn, D Black, A Graham, R Butler, J Riley, R Anand, ... Nucleic acids research 18 (13), 3913-3917, 1990 | 136 | 1990 |
Targeted metabolomics identifies perturbations in amino acid metabolism that sub-classify patients with COPD BK Ubhi, KK Cheng, J Dong, T Janowitz, D Jodrell, R Tal-Singer, ... Molecular BioSystems 8 (12), 3125-3133, 2012 | 123 | 2012 |