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Gene Garrard Olinger Jr.
Gene Garrard Olinger Jr.
Adjunct Professor Medicine, Boston University
Adresse e-mail validée de bu.edu - Page d'accueil
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Année
Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp
X Qiu, G Wong, J Audet, A Bello, L Fernando, JB Alimonti, ...
Nature 514 (7520), 47-53, 2014
12232014
Repurposing of clinically developed drugs for treatment of Middle East respiratory syndrome coronavirus infection
J Dyall, CM Coleman, T Venkataraman, MR Holbrook, J Kindrachuk, ...
Antimicrobial agents and chemotherapy 58 (8), 4885-4893, 2014
7292014
Delayed treatment of Ebola virus infection with plant-derived monoclonal antibodies provides protection in rhesus macaques
GG Olinger Jr, J Pettitt, D Kim, C Working, O Bohorov, B Bratcher, E Hiatt, ...
Proceedings of the National Academy of Sciences 109 (44), 18030-18035, 2012
4532012
Antiviral potential of ERK/MAPK and PI3K/AKT/mTOR signaling modulation for Middle East respiratory syndrome coronavirus infection as identified by temporal kinome analysis
J Kindrachuk, B Ork, S Mazur, MR Holbrook, MB Frieman, D Traynor, ...
Antimicrobial agents and chemotherapy 59 (2), 1088-1099, 2015
4032015
FDA-approved selective estrogen receptor modulators inhibit Ebola virus infection
LM Johansen, JM Brannan, SE Delos, CJ Shoemaker, A Stossel, C Lear, ...
Science translational medicine 5 (190), 190ra79-190ra79, 2013
3782013
Ebola virus-like particle-based vaccine protects nonhuman primates against lethal Ebola virus challenge
KL Warfield, DL Swenson, GG Olinger, WV Kalina, MJ Aman, S Bavari
The Journal of infectious diseases 196 (Supplement_2), S430-S437, 2007
3272007
Evaluation of candidate vaccine approaches for MERS-CoV
L Wang, W Shi, MG Joyce, K Modjarrad, Y Zhang, K Leung, CR Lees, ...
Nature communications 6 (1), 7712, 2015
3182015
Therapeutic intervention of Ebola virus infection in rhesus macaques with the MB-003 monoclonal antibody cocktail
J Pettitt, L Zeitlin, DH Kim, C Working, JC Johnson, O Bohorov, B Bratcher, ...
Science translational medicine 5 (199), 199ra113-199ra113, 2013
2892013
Interferon-β and mycophenolic acid are potent inhibitors of Middle East respiratory syndrome coronavirus in cell-based assays
J Dyall, E Postnikova, H Zhou, J Kindrachuk, RF Johnson, GG Olinger Jr, ...
Journal of general virology 95 (3), 571-577, 2014
2812014
Enhanced potency of a fucose-free monoclonal antibody being developed as an Ebola virus immunoprotectant
L Zeitlin, J Pettitt, C Scully, N Bohorova, D Kim, M Pauly, A Hiatt, L Ngo, ...
Proceedings of the National Academy of Sciences 108 (51), 20690-20694, 2011
2652011
Long-term sequelae after Ebola virus disease in Bundibugyo, Uganda: a retrospective cohort study
DV Clark, H Kibuuka, M Millard, S Wakabi, L Lukwago, A Taylor, MA Eller, ...
The Lancet Infectious Diseases 15 (8), 905-912, 2015
2602015
CD8+ cellular immunity mediates rAd5 vaccine protection against Ebola virus infection of nonhuman primates
NJ Sullivan, L Hensley, C Asiedu, TW Geisbert, D Stanley, J Johnson, ...
Nature medicine 17 (9), 1128-1131, 2011
2572011
A screen of approved drugs and molecular probes identifies therapeutics with anti–Ebola virus activity
LM Johansen, LE DeWald, CJ Shoemaker, BG Hoffstrom, ...
Science translational medicine 7 (290), 290ra89-290ra89, 2015
2562015
Middle East respiratory syndrome and severe acute respiratory syndrome: current therapeutic options and potential targets for novel therapies
J Dyall, R Gross, J Kindrachuk, RF Johnson, GG Olinger Jr, LE Hensley, ...
Drugs 77 (18), 1935-1966, 2017
2182017
Structures of protective antibodies reveal sites of vulnerability on Ebola virus
CD Murin, ML Fusco, ZA Bornholdt, X Qiu, GG Olinger, L Zeitlin, ...
Proceedings of the National Academy of Sciences 111 (48), 17182-17187, 2014
2162014
Gene-specific countermeasures against Ebola virus based on antisense phosphorodiamidate morpholino oligomers
KL Warfield, DL Swenson, GG Olinger, DK Nichols, WD Pratt, R Blouch, ...
PLoS pathogens 2 (1), e1, 2006
1942006
Multiple cationic amphiphiles induce a Niemann-Pick C phenotype and inhibit Ebola virus entry and infection
CJ Shoemaker, KL Schornberg, SE Delos, C Scully, H Pajouhesh, ...
PloS one 8 (2), e56265, 2013
1672013
Mannose-binding lectin binds to Ebola and Marburg envelope glycoproteins, resulting in blocking of virus interaction with DC-SIGN and complement-mediated virus neutralization
X Ji, GG Olinger, S Aris, Y Chen, H Gewurz, GT Spear
Journal of General Virology 86 (9), 2535-2542, 2005
1612005
Induction of humoral and CD8+ T cell responses are required for protection against lethal Ebola virus infection
KL Warfield, G Olinger, EM Deal, DL Swenson, M Bailey, DL Negley, ...
The Journal of Immunology 175 (2), 1184-1191, 2005
1542005
Activation of triggering receptor expressed on myeloid cells-1 on human neutrophils by marburg and ebola viruses
M Mohamadzadeh, SS Coberley, GG Olinger, WV Kalina, G Ruthel, ...
Journal of virology 80 (14), 7235-7244, 2006
1492006
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