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Jonathan Thon
Jonathan Thon
STRM.BIO
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Cytoskeletal mechanics of proplatelet maturation and platelet release
JN Thon, A Montalvo, S Patel-Hett, MT Devine, JL Richardson, A Ehrlicher, ...
Journal of cell biology 191 (4), 861-874, 2010
3622010
Platelets: production, morphology and ultrastructure
JN Thon, JE Italiano
Antiplatelet Agents, 3-22, 2012
3122012
Interpreting the developmental dance of the megakaryocyte: a review of the cellular and molecular processes mediating platelet formation
KR Machlus, JN Thon, JE Italiano Jr
British journal of haematology 165 (2), 227-236, 2014
3112014
Scalable generation of universal platelets from human induced pluripotent stem cells
Q Feng, N Shabrani, JN Thon, H Huo, A Thiel, KR Machlus, K Kim, ...
Stem cell reports 3 (5), 817-831, 2014
2532014
Platelet bioreactor-on-a-chip
JN Thon, L Mazutis, S Wu, JL Sylman, A Ehrlicher, KR Machlus, Q Feng, ...
Blood, The Journal of the American Society of Hematology 124 (12), 1857-1867, 2014
2292014
T granules in human platelets function in TLR9 organization and signaling
JN Thon, CG Peters, KR Machlus, R Aslam, J Rowley, H Macleod, ...
Journal of Cell Biology 198 (4), 561-574, 2012
2282012
Platelets generated from human embryonic stem cells are functional in vitro and in the microcirculation of living mice
SJ Lu, F Li, H Yin, Q Feng, EA Kimbrel, E Hahm, JN Thon, W Wang, ...
Cell research 21 (3), 530-545, 2011
2002011
Platelet formation
JN Thon, JE Italiano
Seminars in hematology 47 (3), 220-226, 2010
1932010
Microtubule and cortical forces determine platelet size during vascular platelet production
JN Thon, H Macleod, AJ Begonja, J Zhu, KC Lee, A Mogilner, JH Hartwig, ...
Nature communications 3 (1), 852, 2012
1642012
Translation of glycoprotein IIIa in stored blood platelets
JN Thon, DV Devine
Transfusion 47 (12), 2260-2270, 2007
1312007
A secreted tyrosine kinase acts in the extracellular environment
MR Bordoli, J Yum, SB Breitkopf, JN Thon, JE Italiano, J Xiao, C Worby, ...
Cell 158 (5), 1033-1044, 2014
1292014
Microtubule sliding drives proplatelet elongation and is dependent on cytoplasmic dynein
M Bender, JN Thon, AJ Ehrlicher, S Wu, L Mazutis, E Deschmann, ...
Blood, The Journal of the American Society of Hematology 125 (5), 860-868, 2015
1182015
Platelet storage lesion: a new understanding from a proteomic perspective
JN Thon, P Schubert, DV Devine
Transfusion medicine reviews 22 (4), 268-279, 2008
1142008
The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation
S Patel-Hett, H Wang, AJ Begonja, JN Thon, EC Alden, NJ Wandersee, ...
Blood, The Journal of the American Society of Hematology 118 (6), 1641-1652, 2011
1082011
Comprehensive proteomic analysis of protein changes during platelet storage requires complementary proteomic approaches
JN Thon, P Schubert, M Duguay, K Serrano, S Lin, J Kast, DV Devine
Transfusion 48 (3), 425-435, 2008
1072008
Does size matter in platelet production?
JN Thon, JE Italiano Jr
Blood, The Journal of the American Society of Hematology 120 (8), 1552-1561, 2012
1042012
High-content live-cell imaging assay used to establish mechanism of trastuzumab emtansine (T-DM1)–mediated inhibition of platelet production
JN Thon, MT Devine, A Jurak Begonja, J Tibbitts, JE Italiano Jr
Blood, The Journal of the American Society of Hematology 120 (10), 1975-1984, 2012
852012
MKL1 and MKL2 play redundant and crucial roles in megakaryocyte maturation and platelet formation
EC Smith, JN Thon, MT Devine, S Lin, VP Schulz, Y Guo, SA Massaro, ...
Blood, The Journal of the American Society of Hematology 120 (11), 2317-2329, 2012
722012
Macrocytic anemia and mitochondriopathy resulting from a defect in sideroflexin 4
GJ Hildick-Smith, JD Cooney, C Garone, LS Kremer, TB Haack, JN Thon, ...
The American Journal of Human Genetics 93 (5), 906-914, 2013
682013
MicroRNAs in platelet biogenesis and function
S Dangwal, T Thum
Thrombosis and haemostasis 108 (10), 599-604, 2012
652012
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