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Kota Nagasaka
Kota Nagasaka
Research Insitute of Molecular Pathology
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Topologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL, and PDS5 proteins
G Wutz, C Várnai, K Nagasaka, DA Cisneros, RR Stocsits, W Tang, ...
The EMBO journal 36 (24), 3573-3599, 2017
6912017
The initial phase of chromosome condensation requires Cdk1-mediated phosphorylation of the CAP-D3 subunit of condensin II
S Abe, K Nagasaka, Y Hirayama, H Kozuka-Hata, M Oyama, Y Aoyagi, ...
Genes & development 25 (8), 863-874, 2011
1772011
ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesinSTAG1 from WAPL
G Wutz, R Ladurner, BG St Hilaire, RR Stocsits, K Nagasaka, B Pignard, ...
Elife 9, e52091, 2020
1192020
Werner syndrome helicase is a selective vulnerability of microsatellite instability-high tumor cells
S Lieb, S Blaha-Ostermann, E Kamper, J Rippka, C Schwarz, ...
Elife 8, e43333, 2019
942019
Absolute quantification of cohesin, CTCF and their regulators in human cells
J Holzmann, AZ Politi, K Nagasaka, M Hantsche-Grininger, N Walther, ...
Elife 8, e46269, 2019
892019
Sister chromatid resolution is an intrinsic part of chromosome organization in prophase
K Nagasaka, MJ Hossain, MJ Roberti, J Ellenberg, T Hirota
Nature cell biology 18 (6), 692-699, 2016
882016
Wapl repression by Pax5 promotes V gene recombination by Igh loop extrusion
L Hill, A Ebert, M Jaritz, G Wutz, K Nagasaka, H Tagoh, ...
Nature 584 (7819), 142-147, 2020
832020
CTCF is a DNA-tension-dependent barrier to cohesin-mediated loop extrusion
IF Davidson, R Barth, M Zaczek, J van der Torre, W Tang, K Nagasaka, ...
Nature 616 (7958), 822-827, 2023
542023
Kinetochore stretching-mediated rapid silencing of the spindle-assembly checkpoint required for failsafe chromosome segregation
KSK Uchida, M Jo, K Nagasaka, M Takahashi, N Shindo, K Shibata, ...
Current Biology 31 (8), 1581-1591. e3, 2021
212021
Cohesin mediates DNA loop extrusion and sister chromatid cohesion by distinct mechanisms
K Nagasaka, IF Davidson, RR Stocsits, W Tang, G Wutz, P Batty, ...
Molecular Cell 83 (17), 3049-3063. e6, 2023
142023
Clarifying the role of condensin in shaping chromosomes
K Nagasaka, T Hirota
Nature Cell Biology 17 (6), 711-713, 2015
32015
Mitosis and meiosis: molecular control of chromosome separation
K Nagasaka, LM Gallego-Paez, T Hirota
eLS, 2011
12011
Cohesin supercoils DNA during loop extrusion
IF Davidson, R Barth, S Horn, R Janissen, K Nagasaka, G Wutz, ...
bioRxiv, 2024.03. 22.586228, 2024
2024
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