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Leonidas Emmanouilidis
Leonidas Emmanouilidis
Adresse e-mail validée de ethz.ch
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Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites
M Dawidowski, L Emmanouilidis, VC Kalel, K Tripsianes, K Schorpp, ...
Science 355 (6332), 1416-1420, 2017
792017
NMR and EPR reveal a compaction of the RNA-binding protein FUS upon droplet formation
L Emmanouilidis, L Esteban-Hofer, FF Damberger, T de Vries, ...
Nature Chemical Biology 17 (5), 608-614, 2021
662021
Structural biology of the import pathways of peroxisomal matrix proteins
L Emmanouilidis, M Gopalswamy, DM Passon, M Wilmanns, M Sattler
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (5), 804-813, 2016
612016
Non-specific adhesive forces between filaments and membraneless organelles
TJ Böddeker, KA Rosowski, D Berchtold, L Emmanouilidis, Y Han, ...
Nature physics 18 (5), 571-578, 2022
472022
Allosteric modulation of peroxisomal membrane protein recognition by farnesylation of the peroxisomal import receptor PEX19
L Emmanouilidis, U Schütz, K Tripsianes, T Madl, J Radke, R Rucktäschel, ...
Nature communications 8 (1), 14635, 2017
452017
Surface tensiometry of phase separated protein and polymer droplets by the sessile drop method
M Ijavi, RW Style, L Emmanouilidis, A Kumar, SM Meier, AL Torzynski, ...
Soft Matter 17 (6), 1655-1662, 2021
342021
Towards the molecular mechanism of the integration of peroxisomal membrane proteins
EA Giannopoulou, L Emmanouilidis, M Sattler, G Dodt, M Wilmanns
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (5), 863-869, 2016
292016
Phase separation of heterogeneous nuclear ribonucleoprotein A1 upon specific RNA‐binding observed by magnetic resonance
I Ritsch, E Lehmann, L Emmanouilidis, M Yulikov, F Allain, G Jeschke
Angewandte Chemie International Edition 61 (40), e202204311, 2022
212022
Structural biology of RNA-binding proteins in the context of phase separation: What NMR and EPR can bring?
L Emmanouilidis, L Esteban-Hofer, G Jeschke, FHT Allain
Current Opinion in Structural Biology 70, 132-138, 2021
212021
Structure–Activity Relationship in Pyrazolo[4,3-c]pyridines, First Inhibitors of PEX14–PEX5 Protein–Protein Interaction with Trypanocidal Activity
M Dawidowski, VC Kalel, V Napolitano, R Fino, K Schorpp, ...
Journal of medicinal chemistry 63 (2), 847-879, 2019
202019
Characterization of weak protein domain structure by spin-label distance distributions
I Ritsch, L Esteban-Hofer, E Lehmann, L Emmanouilidis, M Yulikov, ...
Frontiers in Molecular Biosciences 8, 636599, 2021
142021
Inhibitors of glycosomal protein import provide new leads against trypanosomiasis
VC Kalel, L Emmanouilidis, M Dawidowski, W Schliebs, M Sattler, ...
Microbial Cell 4 (7), 229, 2017
142017
Selective isotope labeling for NMR structure determination of proteins in complex with unlabeled ligands
K Tripsianes, U Schütz, L Emmanouilidis, G Gemmecker, M Sattler
Journal of Biomolecular NMR 73, 183-189, 2019
122019
Phase separation of hnRNP A1 upon specific RNA-binding observed by magnetic resonance
I Ritsch, E Lehmann, L Emmanouilidis, M Yulikov, F Allain, G Jeschke
Biorxiv, 2022.03. 21.485092, 2022
62022
A solid beta-sheet structure is formed at the surface of FUS liquid droplets during aging
L Emmanouilidis, E Bartalucci, Y Kan, M Ijavi, ME Pérez, P Afanasyev, ...
bioRxiv, 2023.06. 02.542764, 2023
52023
Allosteric modulation of peroxisomal membrane protein recognition by farnesylation of the peroxisomal import receptor PEX19. Nat. Commun. 8: 14635
L Emmanouilidis, U Schutz, K Tripsianes, T Madl, J Radke, R Rucktaschel, ...
42017
A solid beta-sheet structure is formed at the surface of FUS droplets during aging
L Emmanouilidis, E Bartalucci, Y Kan, M Ijavi, ME Pérez, P Afanasyev, ...
Nature Chemical Biology, 1-9, 2024
12024
Phasentrennung von heterogenem nuklearem Ribonukleoprotein A1 bei spezifischer RNA‐Bindung, beobachtet durch magnetische Resonanzspektroskopie
I Ritsch, E Lehmann, L Emmanouilidis, M Yulikov, F Allain, G Jeschke
Angewandte Chemie 134 (40), e202204311, 2022
12022
Pyrazolopyridine derivatives and their use in therapy
M Sattler, G Popowicz, M Dawidowski, L Emmanouilidis, R Erdmann, ...
US Patent 10,138,242, 2018
12018
Pyrazolopyridine derivatives and their use in therapy
M Sattler, G Popowicz, M Dawidowski, L Emmanouilidis, R Erdmann, ...
US Patent 9,840,504, 2017
12017
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