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C/EBPα regulates hepatic transcription of hepcidin, an antimicrobial peptide and regulator of iron metabolism: cross-talk between C/EBP pathway and iron metabolism B Courselaud, C Pigeon, Y Inoue, J Inoue, FJ Gonzalez, P Leroyer, ... Journal of Biological Chemistry 277 (43), 41163-41170, 2002 | 313 | 2002 |
The hepatitis C virus NS2 protein is an inhibitor of CIDE-B-induced apoptosis L Erdtmann, N Franck, H Lerat, J Le Seyec, D Gilot, I Cannie, P Gripon, ... Journal of Biological Chemistry 278 (20), 18256-18264, 2003 | 195 | 2003 |
The powerful world of antisense oligonucleotides: From bench to bedside AM Quemener, L Bachelot, A Forestier, E Donnou‐Fournet, D Gilot, ... Wiley Interdisciplinary Reviews: RNA 11 (5), e1594, 2020 | 174 | 2020 |
Interleukin-8 induction by the environmental contaminant benzo (a) pyrene is aryl hydrocarbon receptor-dependent and leads to lung inflammation N Podechard, V Lecureur, E Le Ferrec, I Guenon, L Sparfel, D Gilot, ... Toxicology letters 177 (2), 130-137, 2008 | 147 | 2008 |
PI3K-FRAP/mTOR pathway is critical for hepatocyte proliferation whereas MEK/ERK supports both proliferation and survival A Coutant, C Rescan, D Gilot, P Loyer, C Guguen-Guillouzo, G Baffet Hepatology 36 (5), 1079-1088, 2002 | 147 | 2002 |
Aryl hydrocarbon receptor-and calcium-dependent induction of the chemokine CCL1 by the environmental contaminant benzo [a] pyrene M N'Diaye, E Le Ferrec, D Lagadic-Gossmann, S Corre, D Gilot, ... Journal of Biological Chemistry 281 (29), 19906-19915, 2006 | 130 | 2006 |
ERK-dependent induction of TNFα expression by the environmental contaminant benzo (a) pyrene in primary human macrophages V Lecureur, E Le Ferrec, M N’diaye, M Le Vee, C Gardyn, D Gilot, ... FEBS letters 579 (9), 1904-1910, 2005 | 129 | 2005 |
Liver protection from apoptosis requires both blockage of initiator caspase activities and inhibition of ASK1/JNK pathway via glutathione S-transferase regulation D Gilot, P Loyer, A Corlu, D Glaise, D Lagadic-Gossmann, A Atfi, F Morel, ... Journal of Biological Chemistry 277 (51), 49220-49229, 2002 | 126 | 2002 |
Overexpression of active Aurora-C kinase results in cell transformation and tumour formation J Khan, F Ezan, JY Crémet, A Fautrel, D Gilot, M Lambert, C Benaud, ... PloS one 6 (10), e26512, 2011 | 102 | 2011 |
Antiproliferative and apoptotic effects of O-Trensox, a new synthetic iron chelator, on differentiated human hepatoma cell lines N Rakba, P Loyer, D Gilot, JG Delcros, D Glaise, P Baret, JL Pierre, ... Carcinogenesis 21 (5), 943-951, 2000 | 95 | 2000 |
Regulation and role of p21 and p27 cyclin-dependent kinase inhibitors during hepatocyte differentiation and growth GP Ilyin, D Glaise, D Gilot, G Baffet, C Guguen-Guillouzo American Journal of Physiology-Gastrointestinal and Liver Physiology 285 (1 …, 2003 | 91 | 2003 |
Cytochrome P450-dependent toxicity of environmental polycyclic aromatic hydrocarbons towards human macrophages J van Grevenynghe, L Sparfel, M Le Vee, D Gilot, B Drenou, R Fauchet, ... Biochemical and Biophysical Research Communications 317 (3), 708-716, 2004 | 82 | 2004 |
Sustained activation of the Aryl hydrocarbon Receptor transcription factor promotes resistance to BRAF-inhibitors in melanoma S Corre, N Tardif, N Mouchet, HM Leclair, L Boussemart, A Gautron, ... Nature communications 9 (1), 4775, 2018 | 81 | 2018 |
A non-coding function of TYRP1 mRNA promotes melanoma growth D Gilot, M Migault, L Bachelot, F Journé, A Rogiers, E Donnou-Fournet, ... Nature cell biology 19 (11), 1348-1357, 2017 | 77 | 2017 |
AhR and Arnt differentially regulate NF-κB signaling and chemokine responses in human bronchial epithelial cells J Øvrevik, M Låg, V Lecureur, D Gilot, D Lagadic-Gossmann, M Refsnes, ... Cell Communication and Signaling 12 (1), 1-17, 2014 | 76 | 2014 |
Dioxin-mediated up-regulation of aryl hydrocarbon receptor target genes is dependent on the calcium/calmodulin/CaMKIα pathway P Monteiro, D Gilot, E Le Ferrec, C Rauch, D Lagadic-Gossmann, ... Molecular Pharmacology 73 (3), 769-777, 2008 | 75 | 2008 |
Cisplatin-induced apoptosis involves a Fas-ROCK-ezrin-dependent actin remodelling in human colon cancer cells A Rebillard, S Jouan-Lanhouet, E Jouan, P Legembre, M Pizon, ... European journal of cancer 46 (8), 1445-1455, 2010 | 63 | 2010 |
A role for caspase-8 and c-FLIP L in proliferation and cell-cycle progression of primary hepatocytes D Gilot, AL Serandour, GP Ilyin, D Lagadic-Gossmann, P Loyer, A Corlu, ... Carcinogenesis 26 (12), 2086-2094, 2005 | 59 | 2005 |
Multiple division cycles and long‐term survival of hepatocytes are distinctly regulated by extracellular signal‐regulated kinases ERK1 and ERK2 C Frémin, A Bessard, F Ezan, L Gailhouste, M Régeard, J Le Seyec, ... Hepatology 49 (3), 930-939, 2009 | 53 | 2009 |