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Robert V. Farese, Jr.
Robert V. Farese, Jr.
Professor, Sloan Kettering Institute and Memorial Sloan Kettering Cancer Center
Adresse e-mail validée de mskcc.org - Page d'accueil
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Triglyceride accumulation protects against fatty acid-induced lipotoxicity
LL Listenberger, X Han, SE Lewis, S Cases, RV Farese Jr, DS Ory, ...
Proceedings of the National Academy of Sciences 100 (6), 3077-3082, 2003
21682003
Cellular fatty acid metabolism and cancer
E Currie, A Schulze, R Zechner, TC Walther, RV Farese
Cell metabolism 18 (2), 153-161, 2013
18802013
SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation
MD Hirschey, T Shimazu, E Goetzman, E Jing, B Schwer, DB Lombard, ...
Nature 464 (7285), 121-125, 2010
17342010
Lipid droplets and cellular lipid metabolism
TC Walther, RV Farese Jr
Annual review of biochemistry 81, 687-714, 2012
16512012
Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor
T Shimazu, MD Hirschey, J Newman, W He, K Shirakawa, N Le Moan, ...
Science 339 (6116), 211-214, 2013
15792013
Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation
DB Lombard, FW Alt, HL Cheng, J Bunkenborg, RS Streeper, ...
Molecular and cellular biology 27 (24), 8807-8814, 2007
13852007
Identification of a gene encoding an acyl CoA: diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis
S Cases, SJ Smith, YW Zheng, HM Myers, SR Lear, E Sande, S Novak, ...
Proceedings of the National Academy of Sciences 95 (22), 13018-13023, 1998
13581998
Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in CC chemokine receptor 2 knockout mice.
L Boring, J Gosling, SW Chensue, SL Kunkel, RV Farese, HE Broxmeyer, ...
The Journal of clinical investigation 100 (10), 2552-2561, 1997
13521997
A dual thrombin receptor system for platelet activation
ML Kahn, YW Zheng, W Huang, V Bigornia, D Zeng, S Moff, RV Farese Jr, ...
Nature 394 (6694), 690-694, 1998
13011998
Thematic review series: glycerolipids. DGAT enzymes and triacylglycerol biosynthesis
CLE Yen, SJ Stone, S Koliwad, C Harris, RV Farese
Journal of lipid research 49 (11), 2283-2301, 2008
11872008
Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat
SJ Smith, S Cases, DR Jensen, HC Chen, E Sande, B Tow, DA Sanan, ...
Nature genetics 25 (1), 87-90, 2000
10922000
Lipid droplets finally get a little RESPECT
RV Farese, TC Walther
Cell 139 (5), 855-860, 2009
10912009
The biophysics and cell biology of lipid droplets
AR Thiam, RV Farese Jr, TC Walther
Nature reviews Molecular cell biology 14 (12), 775-786, 2013
9922013
Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members
S Cases, SJ Stone, P Zhou, E Yen, B Tow, KD Lardizabal, T Voelker, ...
Journal of Biological Chemistry 276 (42), 38870-38876, 2001
9562001
SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome
MD Hirschey, T Shimazu, E Jing, CA Grueter, AM Collins, B Aouizerat, ...
Molecular cell 44 (2), 177-190, 2011
8332011
Triacylglycerol synthesis enzymes mediate lipid droplet growth by relocalizing from the ER to lipid droplets
F Wilfling, H Wang, JT Haas, N Krahmer, TJ Gould, A Uchida, JX Cheng, ...
Developmental cell 24 (4), 384-399, 2013
8092013
A guide to analysis of mouse energy metabolism
MH Tschöp, JR Speakman, JRS Arch, J Auwerx, JC Brüning, L Chan, ...
Nature methods 9 (1), 57-63, 2012
7872012
Functional genomic screen reveals genes involved in lipid-droplet formation and utilization
Y Guo, TC Walther, M Rao, N Stuurman, G Goshima, K Terayama, ...
Nature 453 (7195), 657-661, 2008
7842008
Lipopenia and skin barrier abnormalities in DGAT2-deficient mice
SJ Stone, HM Myers, SM Watkins, BE Brown, KR Feingold, PM Elias, ...
Journal of Biological Chemistry 279 (12), 11767-11776, 2004
7042004
Progranulin deficiency promotes circuit-specific synaptic pruning by microglia via complement activation
H Lui, J Zhang, SR Makinson, MK Cahill, KW Kelley, HY Huang, Y Shang, ...
Cell 165 (4), 921-935, 2016
6522016
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