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Kiran M Patil
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Incorporating a guanidine-modified cytosine base into triplex-forming PNAs for the recognition of a CG pyrimidine–purine inversion site of an RNA duplex
DFK Toh, G Devi, KM Patil, Q Qu, M Maraswami, Y Xiao, TP Loh, Y Zhao, ...
Nucleic acids research 44 (19), 9071-9082, 2016
502016
A short chemically modified dsRNA-binding PNA (dbPNA) inhibits influenza viral replication by targeting viral RNA panhandle structure
J Kesy, KM Patil, SR Kumar, Z Shu, HY Yong, L Zimmermann, AAL Ong, ...
Bioconjugate Chemistry 30 (3), 931-943, 2019
452019
Highly efficient (RXR)-type carbamates as molecular transporters for cellular delivery
KM Patil, RJ Naik, Rajpal, M Fernandes, M Ganguli, VA Kumar
Journal of the American Chemical Society 134 (17), 7196-7199, 2012
432012
Nanopore Sequencing Accurately Identifies the Mutagenic DNA Lesion O6‐Carboxymethyl Guanine and Reveals Its Behavior in Replication
Y Wang, KM Patil, S Yan, P Zhang, W Guo, Y Wang, HY Chen, ...
Angewandte Chemie International Edition 58 (25), 8432-8436, 2019
352019
G4-PROTAC: targeted degradation of a G-quadruplex binding protein
H LingáSeah, K WaiáLim, A TuÔnáPhan
Chemical Communications 57 (95), 12816-12819, 2021
312021
Incorporating uracil and 5-halouracils into short peptide nucleic acids for enhanced recognition of A–U pairs in dsRNAs
KM Patil, DFK Toh, Z Yuan, Z Meng, Z Shu, H Zhang, AAL Ong, ...
Nucleic Acids Research 46 (15), 7506-7521, 2018
292018
Selective binding to mRNA duplex regions by chemically modified peptide nucleic acids stimulates ribosomal frameshifting
RY Puah, H Jia, M Maraswami, DF Kaixin Toh, R Ero, L Yang, KM Patil, ...
Biochemistry 57 (1), 149-159, 2018
262018
General recognition of UG, UA, and CG pairs by double-stranded RNA-binding PNAs incorporated with an artificial nucleobase
AAL Ong, DFK Toh, KM Patil, Z Meng, Z Yuan, MS Krishna, G Devi, ...
Biochemistry 58 (10), 1319-1331, 2019
222019
RNA secondary structure-based design of antisense peptide nucleic acids for modulating disease-associated aberrant tau pre-mRNA alternative splicing
AAL Ong, J Tan, M Bhadra, C Dezanet, KM Patil, MS Chong, R Kierzek, ...
Molecules 24 (16), 3020, 2019
192019
Incorporating 2-thiouracil into short double-stranded RNA-binding peptide nucleic acids for enhanced recognition of AU pairs and for targeting a microRNA hairpin precursor
AAL Ong, DFK Toh, MS Krishna, KM Patil, K Okamura, G Chen
Biochemistry 58 (32), 3444-3453, 2019
182019
Second generation, arginine-rich (R–X′–R) 4-type cell-penetrating α–ω–α-peptides with constrained, chiral ω-amino acids (X′) for enhanced cargo delivery into cells
KM Patil, RJ Naik, M Vij, AK Yadav, VA Kumar, M Ganguli, M Fernandes
Bioorganic & Medicinal Chemistry Letters 24 (17), 4198-4202, 2014
162014
Targeting RNA editing of antizyme inhibitor 1: A potential oligonucleotide-based antisense therapy for cancer
DJT Tay, Y Song, B Peng, TB Toh, L Hooi, DFK Toh, HQ Hong, SJ Tang, ...
Molecular therapy 29 (11), 3258-3273, 2021
132021
A new water soluble copper N-heterocyclic carbene complex delivers mild O 6 G-selective RNA alkylation
D Rasale, K Patil, B Sauter, S Geigle, S Zhanybekova, D Gillingham
Chemical communications 54 (66), 9174-9177, 2018
112018
Sequence-specific and selective recognition of double-stranded RNAs over single-stranded RNAs by chemically modified peptide nucleic acids
DFK Toh, KM Patil, G Chen
JoVE (Journal of Visualized Experiments), e56221, 2017
112017
Recognition of RNA sequence and structure by duplex and triplex formation: targeting miRNA and pre-miRNA
KM Patil, G Chen
Modified Nucleic Acids in Biology and Medicine, 299-317, 2016
82016
High Sensitivity of Human Translesion DNA Synthesis Polymerase κ to Variation in O6-Carboxymethylguanine Structures
MH Räz, ES Sandell, KM Patil, DG Gillingham, SJ Sturla
ACS chemical biology 14 (2), 214-222, 2019
62019
Modified Nucleic Acids in Biology and Medicine
KM Patil, G Chen, S Jurga, VA Erdmann, J Barciszewski
Erdmann, VA, Jurga, S., Barciszewski, J., Eds, 2016
62016
Efficient Cellular Entry of (rxr)-Type Carbamate–Plasmid DNA Complexes and Its Implication for Noninvasive Topical DNA Delivery to Skin
M Vij, P Natarajan, AK Yadav, KM Patil, T Pandey, N Gupta, D Santhiya, ...
Molecular Pharmaceutics 13 (6), 1779-1790, 2016
52016
159. RXR-Carbamate–A Novel Molecular Transporter for Skin
P Natarajan, KM Patil, M Vij, AK Yadav, VA Kumar, M Ganguli, ...
Molecular Therapy 23, S64, 2015
2015
Design, synthesis and evaluation of amino-and guanidino-substituted oligomers and oligonucleotides for better cellular uptake
KM Patil
CSIR-National Chemical Laboratory, Pune, 2013
2013
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