| Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity V Sorrentino, M Romani, L Mouchiroud, JS Beck, H Zhang, D D’Amico, ... Nature 552 (7684), 187-193, 2017 | 538 | 2017 |
| NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation D Ryu, H Zhang, ER Ropelle, V Sorrentino, DAG Mázala, L Mouchiroud, ... Science translational medicine 8 (361), 361ra139-361ra139, 2016 | 278 | 2016 |
| Repairing Mitochondrial Dysfunction in Disease V Sorrentino, KJ Menzies, J Auwerx Annual Review of Pharmacology and Toxicology 58 (1), 2018 | 243 | 2018 |
| PPARδ Promotes Running Endurance by Preserving Glucose ERM Fan W, Waizenegger W, Lin CS, Sorrentino V, He MX, Wall CE, Li H, Liddle ... cell metabolism 25 (5), 1186-1193., 2017 | 195 | 2017 |
| The E3 ubiquitin ligase IDOL induces the degradation of the low density lipoprotein receptor family members VLDLR and ApoER2 C Hong, S Duit, P Jalonen, R Out, L Scheer, V Sorrentino, R Boyadjian, ... Journal of Biological Chemistry 285 (26), 19720-19726, 2010 | 145 | 2010 |
| The RNA-binding protein PUM2 impairs mitochondrial dynamics and mitophagy during aging D D’Amico, A Mottis, F Potenza, V Sorrentino, H Li, M Romani, V Lemos, ... Molecular cell 73 (4), 775-787. e10, 2019 | 112 | 2019 |
| Cytosolic Proteostasis Networks of the Mitochondrial Stress Response D D'Amico, V Sorrentino, J Auwerx Trends in Biochemical Sciences 42 (9), 712-725, 2017 | 112 | 2017 |
| Post-transcriptional regulation of lipoprotein receptors by the E3-ubiquitin ligase inducible degrader of the low-density lipoprotein receptor V Sorrentino, N Zelcer Current opinion in lipidology 23 (3), 213-219, 2012 | 103 | 2012 |
| The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation V Sorrentino, JK Nelson, E Maspero, ARA Marques, L Scheer, S Polo, ... Journal of lipid research 54 (8), 2174-2184, 2013 | 70 | 2013 |
| Bayesian association scan reveals loci associated with human lifespan and linked biomarkers AF McDaid, PK Joshi, E Porcu, A Komljenovic, H Li, V Sorrentino, ... Nature communications 8 (1), 15842, 2017 | 69 | 2017 |
| Identification of a loss-of-function inducible degrader of the low-density lipoprotein receptor variant in individuals with low circulating low-density lipoprotein V Sorrentino, SW Fouchier, MM Motazacker, JK Nelson, JC Defesche, ... European heart journal 34 (17), 1292-1297, 2013 | 69 | 2013 |
| A frameshift mutation in LRSAM1 is responsible for a dominant hereditary polyneuropathy MAJ Weterman, V Sorrentino, PR Kasher, ME Jakobs, BGM van Engelen, ... Human molecular genetics 21 (2), 358-370, 2012 | 69 | 2012 |
| Automated longitudinal monitoring of in vivo protein aggregation in neurodegenerative disease C. elegans models M Cornaglia, G Krishnamani, L Mouchiroud, V Sorrentino, T Lehnert, ... Molecular neurodegeneration 11, 1-13, 2016 | 62 | 2016 |
| Distinct functional domains contribute to degradation of the low density lipoprotein receptor (LDLR) by the E3 ubiquitin ligase inducible Degrader of the LDLR (IDOL) V Sorrentino, L Scheer, A Santos, E Reits, B Bleijlevens, N Zelcer Journal of Biological Chemistry 286 (34), 30190-30199, 2011 | 59 | 2011 |
| NAD+ boosting reduces age-associated amyloidosis and restores mitochondrial homeostasis in muscle M Romani, V Sorrentino, CM Oh, H Li, TI de Lima, H Zhang, M Shong, ... Cell reports 34 (3), 2021 | 54 | 2021 |
| An integrated systems genetics and omics toolkit to probe gene function H Li, X Wang, D Rukina, Q Huang, T Lin, V Sorrentino, H Zhang, ... Cell systems 6 (1), 90-102. e4, 2018 | 53 | 2018 |
| Deubiquitylase USP2 Regulates the LDLR Pathway by Counteracting the E3-Ubiquitin Ligase IDOL JK Nelson, V Sorrentino, RA Trezza, C Heride, S Urbe, S Distel, N Zelcer Circulation Research, 2015 | 43 | 2015 |
| Identification of the (pro) renin receptor as a novel regulator of low-density lipoprotein metabolism X Lu, ME Meima, JK Nelson, V Sorrentino, A Loregger, S Scheij, ... Circulation Research 118 (2), 222-229, 2016 | 40 | 2016 |
| Identification of the ER-resident E3 ubiquitin ligase RNF145 as a novel LXR-regulated gene ECL Cook, JK Nelson, V Sorrentino, D Koenis, M Moeton, S Scheij, ... PLoS One 12 (2), e0172721, 2017 | 35 | 2017 |
| Microfluidics-enabled phenotyping of a whole population of C. elegans worms over their embryonic and post-embryonic development at single-organism resolution MC Letizia, M Cornaglia, R Trouillon, V Sorrentino, L Mouchiroud, ... Microsystems & nanoengineering 4 (1), 6, 2018 | 31 | 2018 |
Johan AuwerxProfessor at the EPFLAdresse e-mail validée de epfl.ch
