| Systematic identification of trans eQTLs as putative drivers of known disease associations HJ Westra, MJ Peters, T Esko, H Yaghootkar, C Schurmann, J Kettunen, ... Nature genetics 45 (10), 1238-1243, 2013 | 1652 | 2013 |
| Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression BP Fairfax, P Humburg, S Makino, V Naranbhai, D Wong, E Lau, L Jostins, ... Science 343 (6175), 1246949, 2014 | 677 | 2014 |
| Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus J Bentham, DL Morris, DSC Graham, CL Pinder, P Tombleson, ... Nature genetics 47 (12), 1457-1464, 2015 | 544 | 2015 |
| Genetics of gene expression in primary immune cells identifies cell type–specific master regulators and roles of HLA alleles BP Fairfax, S Makino, J Radhakrishnan, K Plant, S Leslie, A Dilthey, ... Nature genetics 44 (5), 502-510, 2012 | 508 | 2012 |
| Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis U Vősa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ... BioRxiv, 447367, 2018 | 347 | 2018 |
| A common haplotype lowers PU. 1 expression in myeloid cells and delays onset of Alzheimer's disease K Huang, E Marcora, AA Pimenova, AF Di Narzo, M Kapoor, SC Jin, ... Nature neuroscience 20 (8), 1052-1061, 2017 | 259 | 2017 |
| Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization K Břnnelykke, MC Matheson, TH Pers, R Granell, DP Strachan, AC Alves, ... Nature genetics 45 (8), 902-906, 2013 | 244 | 2013 |
| Phospho-dependent functional modulation of GABAB receptors by the metabolic sensor AMP-dependent protein kinase N Kuramoto, ME Wilkins, BP Fairfax, R Revilla-Sanchez, M Terunuma, ... Neuron 53 (2), 233-247, 2007 | 206 | 2007 |
| Leprosy and the adaptation of human toll-like receptor 1 SH Wong, S Gochhait, D Malhotra, FH Pettersson, YY Teo, CC Khor, ... PLoS pathogens 6 (7), e1000979, 2010 | 167 | 2010 |
| Genomic modulators of gene expression in human neutrophils V Naranbhai, BP Fairfax, S Makino, P Humburg, D Wong, E Ng, AVS Hill, ... Nature communications 6 (1), 1-13, 2015 | 139 | 2015 |
| Peripheral CD8+ T cell characteristics associated with durable responses to immune checkpoint blockade in patients with metastatic melanoma BP Fairfax, CA Taylor, RA Watson, I Nassiri, S Danielli, H Fang, EA Mahé, ... Nature medicine 26 (2), 193-199, 2020 | 119 | 2020 |
| Phosphorylation and chronic agonist treatment atypically modulate GABAB receptor cell surface stability BP Fairfax, JA Pitcher, MGH Scott, AR Calver, MN Pangalos, SJ Moss, ... Journal of Biological Chemistry 279 (13), 12565-12573, 2004 | 118 | 2004 |
| Cell specific eQTL analysis without sorting cells HJ Westra, D Arends, T Esko, MJ Peters, C Schurmann, K Schramm, ... PLoS genetics 11 (5), e1005223, 2015 | 109 | 2015 |
| Unique transcriptome signatures and GM-CSF expression in lymphocytes from patients with spondyloarthritis MH Al-Mossawi, L Chen, H Fang, A Ridley, J De Wit, N Yager, ... Nature communications 8 (1), 1-11, 2017 | 100 | 2017 |
| A genetics-led approach defines the drug target landscape of 30 immune-related traits H Fang, H De Wolf, B Knezevic, KL Burnham, J Osgood, A Sanniti, ... Nature genetics 51 (7), 1082-1091, 2019 | 98 | 2019 |
| Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4+ versus CD8+ T cells S Kasela, K Kisand, L Tserel, E Kaleviste, A Remm, K Fischer, T Esko, ... PLoS genetics 13 (3), e1006643, 2017 | 94 | 2017 |
| Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals Y Guo, MB Lanktree, KC Taylor, H Hakonarson, LA Lange, BJ Keating, ... Human molecular genetics 22 (1), 184-201, 2013 | 88 | 2013 |
| Large-scale cis-and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression U Vősa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ... Nature genetics 53 (9), 1300-1310, 2021 | 77 | 2021 |
| Pervasive haplotypic variation in the spliceo-transcriptome of the human major histocompatibility complex C Vandiedonck, MS Taylor, HE Lockstone, K Plant, JM Taylor, C Durrant, ... Genome research 21 (7), 1042-1054, 2011 | 74 | 2011 |
| Distinct transcriptional and anti-mycobacterial profiles of peripheral blood monocytes dependent on the ratio of monocytes: lymphocytes V Naranbhai, HA Fletcher, R Tanner, MK O'Shea, H McShane, BP Fairfax, ... EBioMedicine 2 (11), 1619-1626, 2015 | 67 | 2015 |
Julian KnightProfessor of Genomic Medicine, University of OxfordVerified email at well.ox.ac.uk
