|Identification of selective inhibitors of cancer stem cells by high-throughput screening|
PB Gupta, TT Onder, G Jiang, K Tao, C Kuperwasser, RA Weinberg, ...
Cell 138 (4), 645-659, 2009
|Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells|
PB Gupta, CM Fillmore, G Jiang, SD Shapira, K Tao, C Kuperwasser, ...
Cell 146 (4), 633-644, 2011
|Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy|
CM Fillmore, C Kuperwasser
Breast cancer research 10 (2), 1-13, 2008
|Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state|
CL Chaffer, I Brueckmann, C Scheel, AJ Kaestli, PA Wiggins, ...
Proceedings of the National Academy of Sciences 108 (19), 7950-7955, 2011
|Reconstruction of functionally normal and malignant human breast tissues in mice|
C Kuperwasser, T Chavarria, M Wu, G Magrane, JW Gray, L Carey, ...
Proceedings of the National Academy of Sciences 101 (14), 4966-4971, 2004
|The melanocyte differentiation program predisposes to metastasis after neoplastic transformation|
PB Gupta, C Kuperwasser, JP Brunet, S Ramaswamy, WL Kuo, JW Gray, ...
Nature genetics 37 (10), 1047-1054, 2005
|A novel lung metastasis signature links Wnt signaling with cancer cell self-renewal and epithelial-mesenchymal transition in basal-like breast cancer|
TA DiMeo, K Anderson, P Phadke, C Feng, CM Perou, S Naber, ...
Cancer research 69 (13), 5364-5373, 2009
|Genetic predisposition directs breast cancer phenotype by dictating progenitor cell fate|
TA Proia, PJ Keller, PB Gupta, I Klebba, AD Jones, M Sedic, H Gilmore, ...
Cell stem cell 8 (2), 149-163, 2011
|Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling|
CM Fillmore, PB Gupta, JA Rudnick, S Caballero, PJ Keller, ES Lander, ...
Proceedings of the National Academy of Sciences 107 (50), 21737-21742, 2010
|Defining the cellular precursors to human breast cancer|
PJ Keller, LM Arendt, A Skibinski, T Logvinenko, I Klebba, S Dong, ...
Proceedings of the National Academy of Sciences 109 (8), 2772-2777, 2012
|A mouse model of human breast cancer metastasis to human bone|
C Kuperwasser, S Dessain, BE Bierbaum, D Garnet, K Sperandio, ...
Cancer research 65 (14), 6130-6138, 2005
|Development of spontaneous mammary tumors in BALB/c p53 heterozygous mice: a model for Li-Fraumeni syndrome|
C Kuperwasser, GD Hurlbut, FS Kittrell, ES Dickinson, R Laucirica, ...
The American journal of pathology 157 (6), 2151-2159, 2000
|A mammary-specific model demonstrates the role of the p53 tumor suppressor gene in tumor development|
DJ Jerry, FS Kittrell, C Kuperwasser, R Laucirica, ES Dickinson, ...
Oncogene 19 (8), 1052-1058, 2000
|Phenotypic plasticity: driver of cancer initiation, progression, and therapy resistance|
PB Gupta, I Pastushenko, A Skibinski, C Blanpain, C Kuperwasser
Cell stem cell 24 (1), 65-78, 2019
|Mapping the cellular and molecular heterogeneity of normal and malignant breast tissues and cultured cell lines|
PJ Keller, AF Lin, LM Arendt, I Klebba, AD Jones, JA Rudnick, TA DiMeo, ...
Breast cancer research 12 (5), 1-17, 2010
|Obesity promotes breast cancer by CCL2-mediated macrophage recruitment and angiogenesis|
LM Arendt, J McCready, PJ Keller, DD Baker, SP Naber, V Seewaldt, ...
Cancer research 73 (19), 6080-6093, 2013
|Human breast cancer stem cell markers CD44 and CD24: enriching for cells with functional properties in mice or in man?|
C Fillmore, C Kuperwasser
Breast cancer research 9 (3), 1-3, 2007
|Systemic stromal effects of estrogen promote the growth of estrogen receptor–negative cancers|
PB Gupta, D Proia, O Cingoz, J Weremowicz, SP Naber, RA Weinberg, ...
Cancer research 67 (5), 2062-2071, 2007
|Reconstruction of human mammary tissues in a mouse model|
DA Proia, C Kuperwasser
Nature protocols 1 (1), 206-214, 2006
|Cyclin D1 kinase activity is required for the self-renewal of mammary stem and progenitor cells that are targets of MMTV-ErbB2 tumorigenesis|
R Jeselsohn, NE Brown, L Arendt, I Klebba, MG Hu, C Kuperwasser, ...
Cancer cell 17 (1), 65-76, 2010