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Xavier Lahaye
Xavier Lahaye
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The capsids of HIV-1 and HIV-2 determine immune detection of the viral cDNA by the innate sensor cGAS in dendritic cells
X Lahaye, T Satoh, M Gentili, S Cerboni, C Conrad, I Hurbain, A El Marjou, ...
Immunity 39 (6), 1132-1142, 2013
4222013
Transmission of innate immune signaling by packaging of cGAMP in viral particles
M Gentili, J Kowal, M Tkach, T Satoh, X Lahaye, C Conrad, M Boyron, ...
Science 349 (6253), 1232-1236, 2015
3002015
Functional characterization of Negri bodies (NBs) in rabies virus-infected cells: Evidence that NBs are sites of viral transcription and replication
X Lahaye, A Vidy, C Pomier, L Obiang, F Harper, Y Gaudin, D Blondel
Journal of virology 83 (16), 7948-7958, 2009
2802009
The N-terminal domain of cGAS determines preferential association with centromeric DNA and innate immune activation in the nucleus
M Gentili, X Lahaye, F Nadalin, GPF Nader, EP Lombardi, S Herve, ...
Cell reports 26 (9), 2377-2393. e13, 2019
2202019
NONO detects the nuclear HIV capsid to promote cGAS-mediated innate immune activation
X Lahaye, M Gentili, A Silvin, C Conrad, L Picard, M Jouve, E Zueva, ...
Cell 175 (2), 488-501. e22, 2018
1952018
Hsp70 protein positively regulates rabies virus infection
X Lahaye, A Vidy, B Fouquet, D Blondel
Journal of virology 86 (9), 4743-4751, 2012
1322012
Extracellular vesicles containing ACE2 efficiently prevent infection by SARS‐CoV‐2 Spike protein‐containing virus
F Cocozza, N Névo, E Piovesana, X Lahaye, J Buchrieser, O Schwartz, ...
Journal of extracellular vesicles 10 (2), e12050, 2020
1162020
Constitutive resistance to viral infection in human CD141+ dendritic cells
A Silvin, CI Yu, X Lahaye, F Imperatore, JB Brault, S Cardinaud, C Becker, ...
Science immunology 2 (13), eaai8071, 2017
992017
Resistance to rabies virus infection conferred by the PMLIV isoform
D Blondel, S Kheddache, X Lahaye, L Dianoux, MK Chelbi-Alix
Journal of virology 84 (20), 10719-10726, 2010
872010
Dual modes of rabies P-protein association with microtubules: a novel strategy to suppress the antiviral response
GW Moseley, X Lahaye, DM Roth, S Oksayan, RP Filmer, CL Rowe, ...
Journal of cell science 122 (20), 3652-3662, 2009
852009
Nuclear envelope protein SUN2 promotes cyclophilin-A-dependent steps of HIV replication
X Lahaye, T Satoh, M Gentili, S Cerboni, A Silvin, C Conrad, ...
Cell reports 15 (4), 879-892, 2016
492016
Let me in: Control of HIV nuclear entry at the nuclear envelope
A Bhargava, X Lahaye, N Manel
Cytokine & growth factor reviews 40, 59-67, 2018
392018
Viral and cellular mechanisms of the innate immune sensing of HIV
X Lahaye, N Manel
Current opinion in virology 11, 55-62, 2015
282015
A comprehensive map of the monocyte-derived dendritic cell transcriptional network engaged upon innate sensing of HIV
JS Johnson, N De Veaux, AW Rives, X Lahaye, SY Lucas, BP Perot, ...
Cell reports 30 (3), 914-931. e9, 2020
192020
Single-cell analysis reveals divergent responses of human dendritic cells to the MVA vaccine
M Döring, K De Azevedo, G Blanco-Rodriguez, F Nadalin, T Satoh, ...
Science Signaling 14 (697), eabd9720, 2021
152021
Inhibition of HIV infection by structural proteins of the inner nuclear membrane is associated with reduced chromatin dynamics
A Bhargava, A Williart, M Maurin, PM Davidson, M Jouve, M Piel, ...
Cell Reports 36 (13), 2021
72021
Primary role of type I interferons for the induction of functionally optimal antigen-specific CD8+ T cells in HIV infection
MP Cabral-Piccin, L Papagno, X Lahaye, F Perdomo-Celis, S Volant, ...
EBioMedicine 91, 2023
42023
Compartimentalisation cellulaire viro-induite: agrésomes, inclusions virales et usines virales
D Blondel, X Lahaye, A Vidy, C Pomier
Virologie (Montrouge) 13 (4), 201-214, 2009
22009
Proceedings of the Frontiers of Retrovirology Conference 2016
I Zurnic, S Hütter, U Lehmann, N Stanke, J Reh, T Kern, F Lindel, ...
Retrovirology 13, 1-40, 2016
12016
Le VIH-2 révèle un mécanisme antiviral de détection par l’immunité innée
X Lahaye, N Manel
médecine/sciences 30 (6-7), 610-613, 2014
1*2014
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