Structure and pharmacology of pentameric receptor channels: from bacteria to brain PJ Corringer, F Poitevin, MS Prevost, L Sauguet, M Delarue, ... Structure 20 (6), 941-956, 2012 | 265 | 2012 |
Cyclodipeptide synthases are a family of tRNA-dependent peptide bond–forming enzymes M Gondry, L Sauguet, P Belin, R Thai, R Amouroux, C Tellier, K Tuphile, ... Nature chemical biology 5 (6), 414-420, 2009 | 247 | 2009 |
Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation L Sauguet, A Shahsavar, F Poitevin, C Huon, A Menny, À Nemecz, ... Proceedings of the National Academy of Sciences 111 (3), 966-971, 2014 | 216 | 2014 |
Structural basis for ion permeation mechanism in pentameric ligand‐gated ion channels L Sauguet, F Poitevin, S Murail, C Van Renterghem, G Moraga‐Cid, ... The EMBO journal 32 (5), 728-741, 2013 | 158 | 2013 |
Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel L Sauguet, RJ Howard, L Malherbe, US Lee, PJ Corringer, R Adron Harris, ... Nature communications 4 (1), 1697, 2013 | 153 | 2013 |
A locally closed conformation of a bacterial pentameric proton-gated ion channel MS Prevost, L Sauguet, H Nury, C Van Renterghem, C Huon, F Poitevin, ... Nature structural & molecular biology 19 (6), 642-649, 2012 | 153 | 2012 |
Cyclodipeptide synthases, a family of class-I aminoacyl-tRNA synthetase-like enzymes involved in non-ribosomal peptide synthesis L Sauguet, M Moutiez, Y Li, P Belin, J Seguin, MH Le Du, R Thai, ... Nucleic acids research 39 (10), 4475-4489, 2011 | 98 | 2011 |
Flexible tethering of primase and DNA Pol α in the eukaryotic primosome R Núñez-Ramírez, S Klinge, L Sauguet, R Melero, MA Recuero-Checa, ... Nucleic acids research 39 (18), 8187-8199, 2011 | 77 | 2011 |
Shared active site architecture between the large subunit of eukaryotic primase and DNA photolyase L Sauguet, S Klinge, RL Perera, JD Maman, L Pellegrini PLoS One 5 (4), e10083, 2010 | 73 | 2010 |
Allosteric and hyperekplexic mutant phenotypes investigated on an α1 glycine receptor transmembrane structure G Moraga-Cid, L Sauguet, C Huon, L Malherbe, C Girard-Blanc, S Petres, ... Proceedings of the National Academy of Sciences 112 (9), 2865-2870, 2015 | 57 | 2015 |
Crystallographic studies of pharmacological sites in pentameric ligand-gated ion channels L Sauguet, A Shahsavar, M Delarue Biochimica et Biophysica Acta (BBA)-General Subjects 1850 (3), 511-523, 2015 | 57 | 2015 |
Shared active site architecture between archaeal PolD and multi-subunit RNA polymerases revealed by X-ray crystallography L Sauguet, P Raia, G Henneke, M Delarue Nature communications 7 (1), 12227, 2016 | 47 | 2016 |
An updated structural classification of replicative DNA polymerases P Raia, M Delarue, L Sauguet Biochemical Society Transactions 47 (1), 239-249, 2019 | 42 | 2019 |
Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA C Madru, G Henneke, P Raia, I Hugonneau-Beaufet, G Pehau-Arnaudet, ... Nature Communications 11 (1), 1591, 2020 | 36 | 2020 |
Sites of anesthetic inhibitory action on a cationic ligand-gated ion channel B Laurent, S Murail, A Shahsavar, L Sauguet, M Delarue, M Baaden Structure 24 (4), 595-605, 2016 | 36 | 2016 |
Structural basis for xenon inhibition in a cationic pentameric ligand-gated ion channel L Sauguet, Z Fourati, T Prange, M Delarue, N Colloc'h PLoS One 11 (2), e0149795, 2016 | 35 | 2016 |
Structural basis for a bimodal allosteric mechanism of general anesthetic modulation in pentameric ligand-gated ion channels Z Fourati, RJ Howard, SA Heusser, H Hu, RR Ruza, L Sauguet, E Lindahl, ... Cell reports 23 (4), 993-1004, 2018 | 33 | 2018 |
Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel H Hu, K Ataka, A Menny, Z Fourati, L Sauguet, PJ Corringer, P Koehl, ... Proceedings of the National Academy of Sciences 115 (52), E12172-E12181, 2018 | 32 | 2018 |
Structure of the DP1–DP2 PolD complex bound with DNA and its implications for the evolutionary history of DNA and RNA polymerases P Raia, M Carroni, E Henry, G Pehau-Arnaudet, S Brûlé, P Béguin, ... PLoS biology 17 (1), e3000122, 2019 | 31 | 2019 |
Genuine open form of the pentameric ligand-gated ion channel GLIC Z Fourati, L Sauguet, M Delarue Acta Crystallographica Section D: Biological Crystallography 71 (3), 454-460, 2015 | 28 | 2015 |