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Jeffrey Benovic
Jeffrey Benovic
Thomas Eakins Professor of Biochemistry and Molecular Biology, Thomas Jefferson University
Verified email at jefferson.edu
Title
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Cited by
Year
β-Arrestin acts as a clathrin adaptor in endocytosis of the β2-adrenergic receptor
OB Goodman Jr, JG Krupnick, F Santini, VV Gurevich, RB Penn, ...
nature 383 (6599), 447-450, 1996
17751996
Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin
RAF Dixon, BK Kobilka, DJ Strader, JL Benovic, HG Dohlman, T Frielle, ...
Nature 321 (6065), 75-79, 1986
17361986
β-Arrestin: a protein that regulates β-adrenergic receptor function
MJ Lohse, JL Benovic, J Codina, MG Caron, RJ Lefkowitz
Science 248 (4962), 1547-1550, 1990
15521990
The role of receptor kinases and arrestins in G protein–coupled receptor regulation
JG Krupnick, JL Benovic
Annual review of pharmacology and toxicology 38 (1), 289-319, 1998
13401998
Role of βγ subunits of G proteins in targeting the β-adrenergic receptor kinase to membrane-bound receptors
JA Pitcher, J Inglese, JB Higgins, JL Arriza, PJ Casey, C Kim, JL Benovic, ...
Science 257 (5074), 1264-1267, 1992
9301992
Beta-adrenergic receptor kinase: identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor.
JL Benovic, RH Strasser, MG Caron, RJ Lefkowitz
Proceedings of the National Academy of Sciences 83 (9), 2797-2801, 1986
9251986
Regulation of transmembrane signaling by receptor phosphorylation
DR Sibley, JL Benovic, MG Caron, RJ Lefkowitz
Cell 48 (6), 913-922, 1987
9001987
Regulation of receptor trafficking by GRKs and arrestins
CAC Moore, SK Milano, JL Benovic
Annu. Rev. Physiol. 69, 451-482, 2007
8472007
Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways
MA Crackower, GY Oudit, I Kozieradzki, R Sarao, H Sun, T Sasaki, ...
Cell 110 (6), 737-749, 2002
7832002
Regulation of CXCR4 signaling
JM Busillo, JL Benovic
Biochimica et Biophysica Acta (BBA)-Biomembranes 1768 (4), 952-963, 2007
7452007
Functional desensitization of the isolated beta-adrenergic receptor by the beta-adrenergic receptor kinase: potential role of an analog of the retinal protein arrestin (48-kDa …
JL Benovic, H Kühn, I Weyand, J Codina, MG Caron, RJ Lefkowitz
Proceedings of the National Academy of Sciences 84 (24), 8879-8882, 1987
6691987
Agonist-promoted ubiquitination of the G protein-coupled receptor CXCR4 mediates lysosomal sorting
A Marchese, JL Benovic
Journal of Biological Chemistry 276 (49), 45509-45512, 2001
5652001
β-Adrenergic receptor kinase: primary structure delineates a multigene family
JL Benovic, A DeBlasi, WC Stone, MG Caron, RJ Lefkowitz
Science 246 (4927), 235-240, 1989
5591989
Regulation of adenylyl cyclase-coupled beta-adrenergic receptors
JL Benovic, M Bouvier, MG Caron, RJ Lefkowitz
Annual review of cell biology 4 (1), 405-428, 1988
5581988
Multiple pathways of rapid beta 2-adrenergic receptor desensitization. Delineation with specific inhibitors.
MJ Lohse, JL Benovic, MG Caron, RJ Lefkowitz
Journal of Biological Chemistry 265 (6), 3209a, 1990
5481990
Synucleins are a novel class of substrates for G protein-coupled receptor kinases
AN Pronin, AJ Morris, A Surguchov, JL Benovic
Journal of Biological Chemistry 275 (34), 26515-26522, 2000
5052000
Arrestin interactions with G protein-coupled receptors: direct binding studies of wild type and mutant arrestins with rhodopsin, β2-adrenergic, and m2 muscarinic cholinergic …
VV Gurevich, SB Dion, JJ Onorato, J Ptasienski, CM Kim, R Sterne-Marr, ...
Journal of Biological Chemistry 270 (2), 720-731, 1995
4801995
Phosphorylation of the mammalian beta-adrenergic receptor by cyclic AMP-dependent protein kinase. Regulation of the rate of receptor phosphorylation and dephosphorylation by …
JL Benovic, LJ Pike, RA Cerione, C Staniszewski, T Yoshimasa, J Codina, ...
Journal of Biological Chemistry 260 (11), 7094-7101, 1985
4681985
The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4
A Marchese, C Raiborg, F Santini, JH Keen, H Stenmark, JL Benovic
Developmental cell 5 (5), 709-722, 2003
4672003
Selective regulation of Gαq/11 by an RGS domain in the G protein-coupled receptor kinase, GRK2
CV Carman, JL Parent, PW Day, AN Pronin, PM Sternweis, ...
Journal of Biological Chemistry 274 (48), 34483-34492, 1999
4191999
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