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Varnika Roy
Varnika Roy
Director, GSK Vaccines
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Year
Cross species quorum quenching using a native AI-2 processing enzyme
V Roy, R Fernandes, CY Tsao, WE Bentley
ACS chemical biology 5 (2), 223-232, 2010
1512010
Developing next generation antimicrobials by intercepting AI-2 mediated quorum sensing
V Roy, BL Adams, WE Bentley
Enzyme and microbial technology 49 (2), 113-123, 2011
1462011
AI-2 analogs and antibiotics: a synergistic approach to reduce bacterial biofilms
V Roy, MT Meyer, JAI Smith, S Gamby, HO Sintim, R Ghodssi, WE Bentley
Applied microbiology and biotechnology 97, 2627-2638, 2013
1232013
Development of a CHO-based cell-free platform for synthesis of active monoclonal antibodies
RW Martin, NI Majewska, CX Chen, TE Albanetti, RBC Jimenez, ...
ACS synthetic biology 6 (7), 1370-1379, 2017
1032017
Engineered biological nanofactories trigger quorum sensing response in targeted bacteria
R Fernandes, V Roy, HC Wu, WE Bentley
Nature nanotechnology 5 (3), 213-217, 2010
952010
Synthetic analogs tailor native AI-2 signaling across bacterial species
V Roy, JAI Smith, J Wang, JE Stewart, WE Bentley, HO Sintim
Journal of the American Chemical Society 132 (32), 11141-11150, 2010
922010
Development and validation of a microfluidic reactor for biofilm monitoring via optical methods
MT Meyer, V Roy, WE Bentley, R Ghodssi
Journal of Micromechanics and Microengineering 21 (5), 054023, 2011
702011
Altering the communication networks of multispecies microbial systems using a diverse toolbox of AI-2 analogues
S Gamby, V Roy, M Guo, JAI Smith, J Wang, JE Stewart, X Wang, ...
ACS chemical biology 7 (6), 1023-1030, 2012
582012
A therapeutic uricase with reduced immunogenicity risk and improved development properties
AC Nyborg, C Ward, A Zacco, B Chacko, L Grinberg, JC Geoghegan, ...
PLoS One 11 (12), e0167935, 2016
542016
Effects on membrane lateral pressure suggest permeation mechanisms for bacterial quorum signaling molecules
K Kamaraju, J Smith, J Wang, V Roy, HO Sintim, WE Bentley, S Sukharev
Biochemistry 50 (32), 6983-6993, 2011
542011
Microfluidic electrochemical sensor array for characterizing protein interactions with various functionalized surfaces
PH Dykstra, V Roy, C Byrd, WE Bentley, R Ghodssi
Analytical chemistry 83 (15), 5920-5927, 2011
492011
Octopus: A dashboard for sensor networks visual control
AG Ruzzelli, R Jurdak, M Dragone, A Barbirato, GMP O’Hare, S Boivineau, ...
Proceeding of the 14th Annual International Conference on Mobile Computing …, 2008
172008
A bicistronic vector with destabilized mRNA secondary structure yields scalable higher titer expression of human neurturin in E. coli
V Roy, R Roth, M Berge, R Chitta, S Vajrala, S Kuntumalla, ...
Biotechnology and Bioengineering 114 (8), 1753-1761, 2017
82017
Phosphorylated and Branched Dihydroxy-Pentane-Dione (DPD) analogs as quorum sensing inhibitors in bacteria
HO Sintim, WE Bentley, V Roy, J Smith, R Ghodssi, MT Meyer
US Patent 8,952,192, 2015
62015
A microfluidic platform for optical absorbance monitoring of bacterial biofilms
MT Meyer, V Roy, WE Bentley, R Ghodssi
SENSORS, 2010 IEEE, 2291-2294, 2010
32010
A Microfluidic Platform for Optical Monitoring of Bacterial Biofilms
MT Meyer, V Roy, WE Bentley, R Ghodssi
26th Southern Biomedical Engineering Conference SBEC 2010, April 30-May 2 …, 2010
12010
Developing an end to end bio-manufacturing platform for the new paradigm of SAM (Self Amplifying mRNA vaccines)
V Roy, M Bugno, D Chinchilla-Olszar, K Forney-Stevens, M Xie, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018
2018
Development of a CHO-based cell-free platform for the synthesis of active monoclonal antibodies as a potential high-throughput screening tool
R Martin, N Majewska, C Chen, A Schmelzer, M Jewett, V Roy
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017
2017
Development of a CHO cell-free synthetic platform for production of monoclonal antibodies
N Majewska, R Martin, K Moore, A Schmelzer, M Jewett, V Roy
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 251, 2016
2016
Increasing soluble expression of an intact Fab (fragmented antibody) in E. coli by smart plasmid design and chaperone co-expression
V Roy, K Bhere, P Navarathna, S Machhi, M Berge, L Qu
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 249, 2015
2015
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