The chemistry and pharmacology of citrus limonoids R Gualdani, MM Cavalluzzi, G Lentini, S Habtemariam Molecules 21 (11), 1530, 2016 | 159 | 2016 |
Ligand efficiency metrics in drug discovery: The pros and cons from a practical perspective MM Cavalluzzi, GF Mangiatordi, O Nicolotti, G Lentini Expert opinion on drug discovery 12 (11), 1087-1104, 2017 | 80 | 2017 |
A mini-review on thalidomide: chemistry, mechanisms of action, therapeutic potential and anti-angiogenic properties in multiple myeloma A Mercurio, G Adriani, A Catalano, A Carocci, L Rao, G Lentini, ... Current medicinal chemistry 24 (25), 2736-2744, 2017 | 80 | 2017 |
Optically active mexiletine analogues as stereoselective blockers of voltage-gated Na+ channels C Franchini, A Carocci, A Catalano, MM Cavalluzzi, F Corbo, G Lentini, ... Journal of medicinal chemistry 46 (24), 5238-5248, 2003 | 66 | 2003 |
New N-(phenoxydecyl) phthalimide derivatives displaying potent inhibition activity towards α-glucosidase R Pascale, A Carocci, A Catalano, G Lentini, A Spagnoletta, ... Bioorganic & medicinal chemistry 18 (16), 5903-5914, 2010 | 58 | 2010 |
Targeting the pregnane X receptor using microbial metabolite mimicry Z Dvořák, F Kopp, CM Costello, JS Kemp, H Li, A Vrzalová, M Štěpánková, ... EMBO molecular medicine 12 (4), e11621, 2020 | 55 | 2020 |
COVID-19, chloroquine repurposing, and cardiac safety concern: chirality might help G Lentini, MM Cavalluzzi, S Habtemariam Molecules 25 (8), 1834, 2020 | 47 | 2020 |
Human ether-à-go-go-related potassium channel: Exploring SAR to improve drug design MM Cavalluzzi, P Imbrici, R Gualdani, A Stefanachi, GF Mangiatordi, ... Drug Discovery Today 25 (2), 344-366, 2020 | 41 | 2020 |
Synthesis of (R)-,(S)-, and (RS)-hydroxymethylmexiletine, one of the major metabolites of mexiletine MM Cavalluzzi, A Catalano, C Bruno, A Lovece, A Carocci, F Corbo, ... Tetrahedron: Asymmetry 18 (20), 2409-2417, 2007 | 41 | 2007 |
One-step synthesis of homochiral O-aryl and O-heteroaryl mandelic acids and their use as efficient 1H NMR chiral solvating agents MM Cavalluzzi, C Bruno, G Lentini, A Lovece, A Catalano, A Carocci, ... Tetrahedron: Asymmetry 20 (17), 1984-1991, 2009 | 38 | 2009 |
Evaluation of the pharmacological activity of the major mexiletine metabolites on skeletal muscle sodium currents M De Bellis, A De Luca, F Rana, MM Cavalluzzi, A Catalano, G Lentini, ... British journal of pharmacology 149 (3), 300-310, 2006 | 38 | 2006 |
Ultrasound and deep eutectic solvents: An efficient combination to tune the mechanism of steviol glycosides extraction G Milani, M Vian, MM Cavalluzzi, C Franchini, F Corbo, G Lentini, ... Ultrasonics Sonochemistry 69, 105255, 2020 | 36 | 2020 |
Antimicrobial and antibiofilm activities of citrus water-extracts obtained by microwave-assisted and conventional methods L Caputo, L Quintieri, MM Cavalluzzi, G Lentini, S Habtemariam Biomedicines 6 (2), 70, 2018 | 36 | 2018 |
N-(Phenoxyalkyl) amides as MT1 and MT2 ligands: Antioxidant properties and inhibition of Ca2+/CaM-dependent kinase II A Carocci, A Catalano, C Bruno, A Lovece, MG Roselli, MM Cavalluzzi, ... Bioorganic & medicinal chemistry 21 (4), 847-851, 2013 | 35 | 2013 |
Facile, alternative route to lubeluzole, its enantiomer, and the racemate C Bruno, A Carocci, A Catalano, MM Cavalluzzi, F Corbo, C Franchini, ... Chirality: The Pharmacological, Biological, and Chemical Consequences of …, 2006 | 30 | 2006 |
Synthesis and evaluation of berberine derivatives and analogs as potential antiacetylcholinesterase and antioxidant agents M Roselli, MM Cavalluzzi, C Bruno, A Lovece, A Carocci, C Franchini, ... Phytochemistry Letters 18, 150-156, 2016 | 29 | 2016 |
Combined modifications of mexiletine pharmacophores for new lead blockers of Nav1. 4 channels M De Bellis, A De Luca, JF Desaphy, R Carbonara, JA Heiny, A Kennedy, ... Biophysical journal 104 (2), 344-354, 2013 | 28 | 2013 |
Nitro-substituted tetrahydroindolizines and homologs: Design, kinetics, and mechanism of α-glucosidase inhibition C Tavani, L Bianchi, A De Palma, GI Passeri, G Punzi, CL Pierri, A Lovece, ... Bioorganic & medicinal chemistry letters 27 (17), 3980-3986, 2017 | 27 | 2017 |
Optimization of Microwave-Assisted Extraction of Antioxidants from Bamboo Shoots of Phyllostachys pubescens G Milani, F Curci, MM Cavalluzzi, P Crupi, I Pisano, G Lentini, ... Molecules 25 (1), 215, 2020 | 26 | 2020 |
Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues M Roselli, A Carocci, R Budriesi, M Micucci, M Toma, LDC Mannelli, ... European Journal of Medicinal Chemistry 121, 300-307, 2016 | 23 | 2016 |