| Inhibition of protein–protein interactions: The discovery of druglike β‐catenin inhibitors by combining virtual and biophysical screening JY Trosset, C Dalvit, S Knapp, M Fasolini, M Veronesi, S Mantegani, ... Proteins: Structure, Function, and Bioinformatics 64 (1), 60-67, 2006 | 221 | 2006 |
| Prodock: Software package for protein modeling and docking JY Trosset, HA Scheraga Journal of computational chemistry 20 (4), 412-427, 1999 | 181 | 1999 |
| Assessment of docking poses: interactions-based accuracy classification (IBAC) versus crystal structure deviations RT Kroemer, A Vulpetti, JJ McDonald, DC Rohrer, JY Trosset, ... Journal of Chemical Information and Computer Sciences 44 (3), 871-881, 2004 | 150 | 2004 |
| Structure of the interferon-receptor complex determined by distance constraints from double-mutant cycles and flexible docking LC Roisman, J Piehler, JY Trosset, HA Scheraga, G Schreiber Proceedings of the National Academy of Sciences 98 (23), 13231-13236, 2001 | 138 | 2001 |
| Reaching the global minimum in docking simulations: a Monte Carlo energy minimization approach using Bezier splines JY Trosset, HA Scheraga Proceedings of the National Academy of Sciences 95 (14), 8011-8015, 1998 | 127 | 1998 |
| Hot spots in Tcf4 for the interaction with β-catenin M Fasolini, X Wu, M Flocco, JY Trosset, U Oppermann, S Knapp Journal of Biological Chemistry 278 (23), 21092-21098, 2003 | 97 | 2003 |
| Synthetic biology for pharmaceutical drug discovery JY Trosset, P Carbonell Drug design, development and therapy, 6285-6302, 2015 | 95 | 2015 |
| Hyperthermostable mutants of Bacillus licheniformis α-amylase: multiple amino acid replacements and molecular modelling N Declerck, P Joyet, JY Trosset, J Garnier, C Gaillardin Protein Engineering, Design and Selection 8 (10), 1029-1037, 1995 | 93 | 1995 |
| Catecholic flavonoids acting as telomerase inhibitors M Menichincheri, D Ballinari, A Bargiotti, L Bonomini, W Ceccarelli, ... Journal of medicinal chemistry 47 (26), 6466-6475, 2004 | 79 | 2004 |
| Pyridopyrimidinones derivatives as telomerase inhibitors M Angiolini, D Ballinari, DF Bassini, L Bonomini, M Gude, ... US Patent 7,019,002, 2006 | 42 | 2006 |
| Structural examination of the influence of phosphorylation on the binding of fibrinopeptide A to bovine thrombin MC Maurer, JL Peng, SS An, JY Trosset, A Henschen-Edman, ... Biochemistry 37 (17), 5888-5902, 1998 | 42 | 1998 |
| Novel scoring functions comprising QXP, SASA, and protein side-chain entropy terms F Giordanetto, S Cotesta, C Catana, JY Trosset, A Vulpetti, PFW Stouten, ... Journal of chemical information and computer sciences 44 (3), 882-893, 2004 | 40 | 2004 |
| Flexible docking simulations: Scaled collective variable Monte Carlo minimization approach using Bezier splines, and comparison with a standard Monte Carlo algorithm JY Trosset, HA Scheraga Journal of computational chemistry 20 (2), 244-252, 1999 | 37 | 1999 |
| Virtual screening to enrich a compound collection with CDK2 inhibitors using docking, scoring, and composite scoring models S Cotesta, F Giordanetto, JY Trosset, P Crivori, RT Kroemer, PFW Stouten, ... Proteins: Structure, Function, and Bioinformatics 60 (4), 629-643, 2005 | 32 | 2005 |
| New general approach for determining the solution structure of a ligand bound weakly to a receptor: structure of a fibrinogen Aα‐like peptide bound to thrombin (S195A) obtained … MC Maurer, JY Trosset, CC Lester, EE DiBella, HA Scheraga Proteins: Structure, Function, and Bioinformatics 34 (1), 29-48, 1999 | 32 | 1999 |
| In silico drug–target profiling JY Trosset, C Cavé Target Identification and Validation in Drug Discovery: Methods and …, 2019 | 29 | 2019 |
| Structure-based target druggability assessment JY Trosset, N Vodovar Target Identification and Validation in Drug Discovery: Methods and …, 2013 | 20 | 2013 |
| Interaction inhibitors of tcf-4 with beta-catenin J Moll, S Knapp, C Dalvit, JY Trosset, M Sundstrom, S Mantegani US Patent App. 10/482,755, 2004 | 19 | 2004 |
| Computational protein design methods for synthetic biology P Carbonell, JY Trosset Computational Methods in Synthetic Biology, 3-21, 2015 | 13 | 2015 |
| An Ockham Razor model of energy metabolism R Khoodeeram, G Bernot, JY Trosset advances in Systems and Synthetic Biology, 1925, 2017 | 12 | 2017 |
