Role of glutathione in the regulation of epigenetic mechanisms in disease JL García-Giménez, C Roma-Mateo, G Perez-Machado, L Peiro-Chova, ... Free Radical Biology and Medicine 112, 36-48, 2017 | 103 | 2017 |
Association studies of OGG1, XRCC1, XRCC2 and XRCC3 polymorphisms with differentiated thyroid cancer WA García-Quispes, G Pérez-Machado, A Akdi, S Pastor, P Galofré, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 709, 67-72, 2011 | 68 | 2011 |
From genetics to epigenetics to unravel the etiology of adolescent idiopathic scoliosis G Pérez-Machado, E Berenguer-Pascual, M Bovea-Marco, ... Bone 140, 115563, 2020 | 55 | 2020 |
Discovery of MAO-B inhibitors-present status and future directions part I: oxygen heterocycles and analogs A M. Helguera, G Perez-Machado, M NDS Cordeiro, F Borges Mini Reviews in Medicinal Chemistry 12 (10), 907, 2012 | 49 | 2012 |
Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening JS Ibáñez-Cabellos, G Pérez-Machado, M Seco-Cervera, ... Redox biology 14, 398-408, 2018 | 33 | 2018 |
Comparative genotoxic evaluation of 2-furylethylenes and 5-nitrofurans by using the comet assay in TK6 cells JI González Borroto, G Pérez Machado, A Creus, R Marcos Mutagenesis 20 (3), 193-197, 2005 | 31 | 2005 |
Oxidative stress and antioxidant response in fibroblasts from Werner and atypical Werner syndromes M Seco-Cervera, M Spis, JL García-Giménez, JS Ibañez-Cabellos, ... Aging (Albany NY) 6 (3), 231, 2014 | 29 | 2014 |
FDA-approved drugs selected using virtual screening bind specifically to G-quadruplex DNA D Castillo-Gonzalez, G Perez-Machado, A Guedin, JL Mergny, ... Current pharmaceutical design 19 (12), 2164-2173, 2013 | 29 | 2013 |
Quantitative structure-activity relationship modelling of the carcinogenic risk of nitroso compounds using regression analysis and the TOPS-MODE approach AM Helguera, G Perez-Machado, M Cordeiro, RD Combes SAR and QSAR in Environmental Research 21 (3-4), 277-304, 2010 | 27 | 2010 |
Harmonization of QSAR best practices and molecular docking provides an efficient virtual screening tool for discovering new G-quadruplex ligands D Castillo-González, JL Mergny, A De Rache, G Pérez-Machado, ... Journal of Chemical Information and Modeling 55 (10), 2094-2110, 2015 | 25 | 2015 |
Common variants of the thyroglobulin gene are associated with differentiated thyroid cancer risk A Akdi, G Pérez, S Pastor, J Castell, J Biarnés, R Marcos, A Velázquez Thyroid 21 (5), 519-525, 2011 | 25 | 2011 |
Oxidative Stress and the Epigenetics of Cell Senescence: Insights from Progeroid Syndromes. C Romá-Mateo, M Seco-Cervera, JS Ibáñez-Cabellos, G Pérez, ... Curr Pharm Des. 24 (40), 4755-4770, 2018 | 22 | 2018 |
Emerging computational approaches for antimicrobial peptide discovery G Agüero-Chapin, D Galpert-Cañizares, D Domínguez-Pérez, ... Antibiotics 11 (7), 936, 2022 | 20 | 2022 |
TI2BioP: Topological Indices to BioPolymers. Its practical use to unravel cryptic bacteriocin-like domains G Agüero-Chapin, G Pérez-Machado, R Molina-Ruiz, Y Pérez-Castillo, ... Amino Acids 40, 431-442, 2011 | 19 | 2011 |
In vitro genotoxicity testing of the furylethylene derivative UC‐245 in human cells G Pérez Machado, JI González Borroto, N Castañedo, A Creus, R Marcos Mutagenesis 19 (1), 75-80, 2004 | 18 | 2004 |
Acute depletion of telomerase components DKC1 and NOP10 induces oxidative stress and disrupts ribosomal biogenesis via NPM1 and activation of the P53 pathway JS Ibáñez-Cabellos, M Seco-Cervera, C Picher-Latorre, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1867 (12), 118845, 2020 | 16 | 2020 |
Graph theory-based sequence descriptors as remote homology predictors G Agüero-Chapin, D Galpert, R Molina-Ruiz, E Ancede-Gallardo, ... Biomolecules 10 (1), 26, 2019 | 16 | 2019 |
Computational tools in the discovery of new G-quadruplex ligands with potential anticancer activity D Castillo-Gonzalez, G Perez-Machado, F Pallardo, TM Garrigues-Pelufo, ... Current Topics in Medicinal Chemistry 12 (24), 2843-2856, 2012 | 12 | 2012 |
Alignment-free methods for the detection and specificity prediction of adenylation domains G Agüero-Chapin, G Pérez-Machado, A Sánchez-Rodríguez, MM Santos, ... Nonribosomal Peptide and Polyketide Biosynthesis: Methods and Protocols, 253-272, 2016 | 10 | 2016 |
Non-linear models based on simple topological indices to identify RNase III protein members G Agüero-Chapin, GA de La Riva, R Molina-Ruiz, A Sánchez-Rodríguez, ... Journal of theoretical biology 273 (1), 167-178, 2011 | 10 | 2011 |