Christoph Merten
Christoph Merten
Professor for Bioengineering, EPFL
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Droplet-based microfluidic platforms for the encapsulation and screening of mammalian cells and multicellular organisms
J Clausell-Tormos, D Lieber, JC Baret, A El-Harrak, OJ Miller, L Frenz, ...
Chemistry & biology 15 (5), 427-437, 2008
Drop-based microfluidic devices for encapsulation of single cells
S Köster, FE Angile, H Duan, JJ Agresti, A Wintner, C Schmitz, AC Rowat, ...
Lab on a Chip 8 (7), 1110-1115, 2008
Droplet-based selection
DA Weitz, A Griffiths, S Koester, VK Mootha, H Duan, J Agresti, C Merten, ...
US Patent App. 13/195,468, 2012
The International Human Epigenome Consortium: a blueprint for scientific collaboration and discovery
HG Stunnenberg, S Abrignani, D Adams, M de Almeida, L Altucci, V Amin, ...
Cell 167 (5), 1145-1149, 2016
Functional single-cell hybridoma screening using droplet-based microfluidics
B El Debs, R Utharala, IV Balyasnikova, AD Griffiths, CA Merten
Proceedings of the National Academy of Sciences 109 (29), 11570-11575, 2012
Droplet-based selection
DA Weitz, A Griffiths, S Koester, VK Mootha, H Duan, J Agresti, C Merten, ...
US Patent App. 12/172,186, 2009
Droplet-based microfluidics in drug discovery, transcriptomics and high-throughput molecular genetics
N Shembekar, C Chaipan, R Utharala, CA Merten
Lab on a Chip 16 (8), 1314-1331, 2016
Imaging of mRNA in live cells using nucleic acid-templated reduction of azidorhodamine probes
Z Pianowski, K Gorska, L Oswald, CA Merten, N Winssinger
Journal of the American Chemical Society 131 (18), 6492-6497, 2009
Miniaturization and parallelization of biological and chemical assays in microfluidic devices
S Vyawahare, AD Griffiths, CA Merten
Chemistry & biology 17 (10), 1052-1065, 2010
An automated two-phase microfluidic system for kinetic analyses and the screening of compound libraries
J Clausell-Tormos, AD Griffiths, CA Merten
Lab on a Chip 10 (10), 1302-1307, 2010
High-throughput screening of enzymes by retroviral display using droplet-based microfluidics
L Granieri, JC Baret, AD Griffiths, CA Merten
Chemistry & biology 17 (3), 229-235, 2010
Circumventing tolerance to the prion protein (PrP): vaccination with PrP-displaying retrovirus particles induces humoral immune responses against the native form of cellular PrP
D Nikles, P Bach, K Boller, CA Merten, F Montrasio, FL Heppner, A Aguzzi, ...
Journal of virology 79 (7), 4033-4042, 2005
Modulation of phase shift between Wnt and Notch signaling oscillations controls mesoderm segmentation
KF Sonnen, VM Lauschke, J Uraji, HJ Falk, Y Petersen, MC Funk, ...
Cell 172 (5), 1079-1090. e12, 2018
Microfluidic devices for diagnostic applications
D Eicher, CA Merten
Expert review of molecular diagnostics 11 (5), 505-519, 2011
A microfluidics platform for combinatorial drug screening on cancer biopsies
F Eduati, R Utharala, D Madhavan, UP Neumann, T Longerich, T Cramer, ...
Nature communications 9 (1), 1-13, 2018
Dynein-based accumulation of membranes regulates nuclear expansion in Xenopus laevis egg extracts
Y Hara, CA Merten
Developmental cell 33 (5), 562-575, 2015
Single-cell droplet microfluidic screening for antibodies specifically binding to target cells
N Shembekar, H Hu, D Eustace, CA Merten
Cell reports 22 (8), 2206-2215, 2018
Efficient cell pairing in droplets using dual-color sorting
H Hu, D Eustace, CA Merten
Lab on a Chip 15 (20), 3989-3993, 2015
Directed evolution of retrovirus envelope protein cytoplasmic tails guided by functional incorporation into lentivirus particles
CA Merten, J Stitz, G Braun, EM Poeschla, K Cichutek, CJ Buchholz
Journal of virology 79 (2), 834-840, 2005
Gouttes et émulsions-Criblage à très haut débit en biologie
JC Baret, V Taly, M Ryckelynck, CA Merten, AD Griffiths
médecine/sciences 25 (6-7), 627-632, 2009
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