| A de novo gain-of-function mutation in SCN11A causes loss of pain perception E Leipold, L Liebmann, GC Korenke, T Heinrich, S Gießelmann, J Baets, ... Nature genetics 45 (11), 1399-1404, 2013 | 319 | 2013 |
| Molecular interaction of δ-conotoxins with voltage-gated sodium channels E Leipold, A Hansel, BM Olivera, H Terlau, SH Heinemann FEBS letters 579 (18), 3881-3884, 2005 | 132 | 2005 |
| Subtype specificity of scorpion β-toxin Tz1 interaction with voltage-gated sodium channels is determined by the pore loop of domain 3 E Leipold, A Hansel, A Borges, SH Heinemann Molecular pharmacology 70 (1), 340-347, 2006 | 108 | 2006 |
| Oxidation of multiple methionine residues impairs rapid sodium channel inactivation M Kassmann, A Hansel, E Leipold, J Birkenbeil, SQ Lu, T Hoshi, ... Pflügers Archiv-European Journal of Physiology 456, 1085-1095, 2008 | 84 | 2008 |
| Cold-aggravated pain in humans caused by a hyperactive NaV1.9 channel mutant E Leipold, A Hanson-Kahn, M Frick, P Gong, JA Bernstein, M Voigt, ... Nature communications 6 (1), 10049, 2015 | 82 | 2015 |
| µO-conotoxins inhibit Nav channels by interfering with their voltage sensors in domain-2 E Leipold, H DeBie, S Zorn, B Adolfo, BM Olivera, H Terlau, ... Channels 1 (4), 253-262, 2007 | 75 | 2007 |
| Combinatorial interaction of scorpion toxins Lqh-2, Lqh-3, and LqhαIT with sodium channel receptor sites-3 E Leipold, S Lu, D Gordon, A Hansel, SH Heinemann Molecular pharmacology 65 (3), 685-691, 2004 | 73 | 2004 |
| The μO‐conotoxin MrVIA inhibits voltage‐gated sodium channels by associating with domain‐3 S Zorn, E Leipold, A Hansel, G Bulaj, BM Olivera, H Terlau, ... FEBS letters 580 (5), 1360-1364, 2006 | 70 | 2006 |
| Structurally Diverse μ‐Conotoxin PIIIA Isomers Block Sodium Channel NaV1. 4 AA Tietze, D Tietze, O Ohlenschläger, E Leipold, F Ullrich, T Kühl, ... Angewandte Chemie-International Edition 51 (17), 4058, 2012 | 68 | 2012 |
| Micro-structured smart hydrogels with enhanced protein loading and release efficiency JT Zhang, S Petersen, M Thunga, E Leipold, R Weidisch, X Liu, A Fahr, ... Acta Biomaterialia 6 (4), 1297-1306, 2010 | 67 | 2010 |
| Isolation, molecular cloning and functional characterization of a novel β-toxin from the Venezuelan scorpion, Tityus zulianus A Borges, MJ Alfonzo, CC Garcı́a, NJ Winand, E Leipold, SH Heinemann Toxicon 43 (6), 671-684, 2004 | 67 | 2004 |
| A novel µ‐conopeptide, CnIIIC, exerts potent and preferential inhibition of NaV1.2/1.4 channels and blocks neuronal nicotinic acetylcholine receptors P Favreau, E Benoit, HG Hocking, L Carlier, D D'hoedt, E Leipold, ... British journal of pharmacology 166 (5), 1654-1668, 2012 | 61 | 2012 |
| New insight in cold pain: role of ion channels, modulation, and clinical perspectives S Lolignier, D Gkika, D Andersson, E Leipold, I Vetter, F Viana, J Noël, ... Journal of Neuroscience 36 (45), 11435-11439, 2016 | 60 | 2016 |
| Differential sensitivity of sodium channels from the central and peripheral nervous system to the scorpion toxins Lqh‐2 and Lqh‐3 Haijun Chen,, SQ Lu, E Leipold, D Gordon, A Hansel, SH Heinemann European Journal of Neuroscience 16 (4), 767-770, 2002 | 59 | 2002 |
| Conotoxins of the O-superfamily affecting voltage-gated sodium channels SH Heinemann, E Leipold Cellular and Molecular Life Sciences 64, 1329-1340, 2007 | 58 | 2007 |
| Scorpion β-toxin interference with NaV channel voltage sensor gives rise to excitatory and depressant modes E Leipold, A Borges, SH Heinemann Journal of General Physiology 139 (4), 305-319, 2012 | 46 | 2012 |
| A room temperature ionic liquid as convenient solvent for the oxidative folding of conopeptides AA Miloslavina, E Leipold, M Kijas, A Stark, SH Heinemann, D Imhof Journal of peptide science: an official publication of the European Peptide …, 2009 | 39 | 2009 |
| Voltage-gated sodium channels and pain T Priestley Current Drug Targets-CNS & Neurological Disorders 3 (6), 441-456, 2004 | 39 | 2004 |
| Effect of depolarization on binding kinetics of scorpion α-toxin highlights conformational changes of rat brain sodium channels N Gilles, E Leipold, H Chen, SH Heinemann, D Gordon Biochemistry 40 (48), 14576-14584, 2001 | 39 | 2001 |
| Heterologous expression of NaV1.9 chimeras in various cell systems RO Goral, E Leipold, E Nematian-Ardestani, SH Heinemann Pflügers Archiv-European Journal of Physiology 467, 2423-2435, 2015 | 37 | 2015 |
