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Thomas Hagan
Thomas Hagan
Adresse e-mail validée de cchmc.org
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Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans
PS Arunachalam, F Wimmers, CKP Mok, RAPM Perera, M Scott, T Hagan, ...
Science 369 (6508), 1210-1220, 2020
10682020
Antibiotics-driven gut microbiome perturbation alters immunity to vaccines in humans
T Hagan, M Cortese, N Rouphael, C Boudreau, C Linde, MS Maddur, ...
Cell 178 (6), 1313-1328. e13, 2019
4642019
Systems vaccinology of the BNT162b2 mRNA vaccine in humans
PS Arunachalam, MKD Scott, T Hagan, C Li, Y Feng, F Wimmers, ...
Nature 596 (7872), 410-416, 2021
3722021
Systems analysis of immunity to influenza vaccination across multiple years and in diverse populations reveals shared molecular signatures
HI Nakaya, T Hagan, SS Duraisingham, EK Lee, M Kwissa, N Rouphael, ...
Immunity 43 (6), 1186-1198, 2015
3002015
Metabolic phenotypes of response to vaccination in humans
S Li, NL Sullivan, N Rouphael, T Yu, S Banton, MS Maddur, ...
Cell 169 (5), 862-877. e17, 2017
2542017
The single-cell epigenomic and transcriptional landscape of immunity to influenza vaccination
F Wimmers, M Donato, A Kuo, T Ashuach, S Gupta, C Li, M Dvorak, ...
Cell 184 (15), 3915-3935. e21, 2021
1552021
Systems vaccinology: enabling rational vaccine design with systems biological approaches
T Hagan, HI Nakaya, S Subramaniam, B Pulendran
Vaccine 33 (40), 5294-5301, 2015
1192015
mTOR regulates metabolic adaptation of APCs in the lung and controls the outcome of allergic inflammation
C Sinclair, G Bommakanti, L Gardinassi, J Loebbermann, MJ Johnson, ...
Science 357 (6355), 1014-1021, 2017
1112017
Engineering cell–material interfaces for long-term expansion of human pluripotent stem cells
CW Chang, Y Hwang, D Brafman, T Hagan, C Phung, S Varghese
Biomaterials 34 (4), 912-921, 2013
652013
Pan-vaccine analysis reveals innate immune endotypes predictive of antibody responses to vaccination
S Fourati, LE Tomalin, MP Mulè, DG Chawla, B Gerritsen, D Rychkov, ...
Nature Immunology 23 (12), 1777-1787, 2022
59*2022
Transcriptional atlas of the human immune response to 13 vaccines reveals a common predictor of vaccine-induced antibody responses
T Hagan, B Gerritsen, LE Tomalin, S Fourati, MP Mulè, DG Chawla, ...
Nature immunology 23 (12), 1788-1798, 2022
522022
Will systems biology deliver its promise and contribute to the development of new or improved vaccines? From data to understanding through systems biology
T Hagan, B Pulendran
Cold Spring Harbor perspectives in biology 10 (8), a028894, 2018
362018
Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: results from the IMPACC study
A Ozonoff, J Schaenman, ND Jayavelu, CE Milliren, CS Calfee, CB Cairns, ...
EBioMedicine 83, 2022
332022
SREBP signaling is essential for effective B cell responses
W Luo, JZ Adamska, C Li, R Verma, Q Liu, T Hagan, F Wimmers, S Gupta, ...
Nature immunology 24 (2), 337-348, 2023
192023
Candida albicans oscillating UME6 expression during intestinal colonization primes systemic Th17 protective immunity
TY Shao, P Kakade, JN Witchley, C Frazer, KL Murray, IV Ene, ...
Cell reports 39 (7), 2022
192022
The immune signatures data resource, a compendium of systems vaccinology datasets
J Diray-Arce, HER Miller, E Henrich, B Gerritsen, MP Mulè, S Fourati, ...
Scientific Data 9 (1), 635, 2022
162022
Multi-omics analysis of mucosal and systemic immunity to SARS-CoV-2 after birth
F Wimmers, AR Burrell, Y Feng, H Zheng, PS Arunachalam, M Hu, ...
Cell 186 (21), 4632-4651. e23, 2023
8*2023
Ablation of Adar1 in myeloid cells imprints a global antiviral state in the lung and heightens early immunity against SARS-CoV-2
JZ Adamska, R Verma, S Gupta, T Hagan, F Wimmers, K Floyd, Q Li, ...
Cell reports 42 (1), 2023
12023
Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: results from the IMPACC study (preprint)
A Ozonoff, J Schaenman, ND Jayavelu, CE Milliren, CS Calfee, CB Cairns, ...
2022
Identification of Markers and Mechanisms in Infection and Immunity
TL Hagan
University of California, San Diego, 2015
2015
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