Jean-Matthieu Prot
Jean-Matthieu Prot
Postdoctorate associate, Cornell University
Adresse e-mail validée de cornell.edu
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Microfabricated mammalian organ systems and their integration into models of whole animals and humans
JH Sung, MB Esch, JM Prot, CJ Long, A Smith, JJ Hickman, ML Shuler
Lab on a Chip 13 (7), 1201-1212, 2013
2102013
How multi-organ microdevices can help foster drug development
MB Esch, AST Smith, JM Prot, C Oleaga, JJ Hickman, ML Shuler
Advanced drug delivery reviews 69, 158-169, 2014
1152014
Multi-cellular 3D human primary liver cell culture elevates metabolic activity under fluidic flow
MB Esch, JM Prot, YI Wang, P Miller, JR Llamas-Vidales, BA Naughton, ...
Lab on a Chip 15 (10), 2269-2277, 2015
1062015
Behavior of HepG2/C3A cell cultures in a microfluidic bioreactor
R Baudoin, L Griscom, JM Prot, C Legallais, E Leclerc
Biochemical Engineering Journal 53 (2), 172-181, 2011
912011
Metabolomics-on-a-chip and predictive systems toxicology in microfluidic bioartificial organs
L Shintu, R Baudoin, V Navratil, JM Prot, C Pontoizeau, M Defernez, ...
Analytical chemistry 84 (4), 1840-1848, 2012
822012
Improvement of HepG2/C3a cell functions in a microfluidic biochip
JM Prot, C Aninat, L Griscom, F Razan, C Brochot, CG Guillouzo, ...
Biotechnology and bioengineering 108 (7), 1704-1715, 2011
782011
A cocktail of metabolic probes demonstrates the relevance of primary human hepatocyte cultures in a microfluidic biochip for pharmaceutical drug screening
JM Prot, O Videau, C Brochot, C Legallais, H Benech, E Leclerc
International journal of pharmaceutics 408 (1-2), 67-75, 2011
542011
First pass intestinal and liver metabolism of paracetamol in a microfluidic platform coupled with a mathematical modeling as a means of evaluating ADME processes in humans
JM Prot, L Maciel, T Bricks, F Merlier, J Cotton, P Paullier, FY Bois, ...
Biotechnology and bioengineering 111 (10), 2027-2040, 2014
512014
Predictive toxicology using systemic biology and liver microfluidic “on chip” approaches: application to acetaminophen injury
JM Prot, A Bunescu, B Elena-Herrmann, C Aninat, LC Snouber, L Griscom, ...
Toxicology and applied pharmacology 259 (3), 270-280, 2012
492012
A phenotypic in vitro model for the main determinants of human whole heart function
M Stancescu, P Molnar, CW McAleer, W McLamb, CJ Long, C Oleaga, ...
Biomaterials 60, 20-30, 2015
412015
Evaluation of seven drug metabolisms and clearances by cryopreserved human primary hepatocytes cultivated in microfluidic biochips
R Baudoin, JM Prot, G Nicolas, J Brocheton, C Brochot, C Legallais, ...
Xenobiotica 43 (2), 140-152, 2013
382013
Integrated proteomic and transcriptomic investigation of the acetaminophen toxicity in liver microfluidic biochip
JM Prot, AS Briffaut, F Letourneur, P Chafey, F Merlier, Y Grandvalet, ...
PloS one 6 (8), e21268, 2011
382011
Metabolomics-on-a-chip and metabolic flux analysis for label-free modeling of the internal metabolism of HepG2/C3A cells
DA Ouattara, JM Prot, A Bunescu, ME Dumas, B Elena-Herrmann, ...
Molecular bioSystems 8 (7), 1908-1920, 2012
362012
Microphysiological systems and low-cost microfluidic platform with analytics
AST Smith, CJ Long, BJ Berry, C McAleer, M Stancescu, P Molnar, ...
Stem cell research & therapy 4 (S1), S9, 2013
232013
Zonation related function and ubiquitination regulation in human hepatocellular carcinoma cells in dynamic vs. static culture conditions
S Cheng, JM Prot, E Leclerc, FY Bois
BMC genomics 13 (1), 1-10, 2012
202012
The current status of alternatives to animal testing and predictive toxicology methods using liver microfluidic biochips
JM Prot, E Leclerc
Annals of biomedical engineering 40 (6), 1228-1243, 2012
202012
‘Body-on-a-Chip’Technology and Supporting Microfluidics
AST Smith, CJ Long, C McAleer, X Guo, M Esch, JM Prot, ML Shuler, ...
Human-based Systems for Translational Research, 132-161, 2014
32014
Qualité opérationnelle pour les laboratoires avec le «5S Biologie»
N Drillaud, C Siaka, A Khalil, L Yin, JM Prot, JP Caliste, G Farges
IRBM News 1 (38), 82-86, 2017
22017
Outil d’autodiagnostic bi-compatible sur le critère HAS 8k et la norme NF S99-170
J Aubertin, S Gadek, S Kopytko, J Séhier, G Farges, JM Prot
IRBM News 3 (36), 113-118, 2015
22015
Evaluation of the mass transfers of caffeine and vitamin B12 in chloroacetaldehyde treated renal barrier model using a microfluidic biochip
C Desrousseaux, JM Prot, M Dufresne, P Paullier, E Leclerc
Sensors and Actuators B: Chemical 174, 465-472, 2012
22012
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