c-Kit—a hematopoietic cell essential receptor tyrosine kinase CE Edling, B Hallberg The international journal of biochemistry & cell biology 39 (11), 1995-1998, 2007 | 354 | 2007 |
Different effects of p14ARF on the levels of ubiquitinated p53 and Mdm2 in vivo D Xirodimas, MK Saville, C Edling, DP Lane, S Lain Oncogene 20 (36), 4972-4983, 2001 | 207 | 2001 |
Class II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic β cells V Dominguez, C Raimondi, S Somanath, M Bugliani, MK Loder, ... Journal of Biological Chemistry 286 (6), 4216-4225, 2011 | 151 | 2011 |
Activation of the MAP kinase pathway by c-Kit is PI-3 kinase dependent in hematopoietic progenitor/stem cell lines E Wandzioch, CE Edling, RH Palmer, L Carlsson, B Hallberg Blood 104 (1), 51-57, 2004 | 137 | 2004 |
Key role of phosphoinositide 3-kinase class IB in pancreatic cancer CE Edling, F Selvaggi, R Buus, T Maffucci, P Di Sebastiano, H Friess, ... Clinical cancer research 16 (20), 4928-4937, 2010 | 114 | 2010 |
GPR55 signalling promotes proliferation of pancreatic cancer cells and tumour growth in mice, and its inhibition increases effects of gemcitabine R Ferro, A Adamska, R Lattanzio, I Mavrommati, CE Edling, SA Arifin, ... Oncogene 37 (49), 6368-6382, 2018 | 101 | 2018 |
Targeting phosphoinositide 3-kinase pathways in pancreatic cancer-from molecular signalling to clinical trials M Falasca, F Selvaggi, R Buus, S Sulpizio, C E Edling Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2011 | 54 | 2011 |
PI3K class IB controls the cell cycle checkpoint promoting cell proliferation in hepatocellular carcinoma F Dituri, A Mazzocca, L Lupo, CE Edling, A Azzariti, S Antonaci, M Falasca, ... International Journal of Cancer 130 (11), 2505-2513, 2012 | 48 | 2012 |
Caffeine and the analog CGS 15943 inhibit cancer cell growth by targeting the phosphoinositide 3-kinase/Akt pathway CE Edling, F Selvaggi, R Ghonaim, T Maffucci, M Falasca Cancer biology & therapy 15 (5), 524-532, 2014 | 35 | 2014 |
Circulating microRNA as a biomarker for coronary artery disease IT Fazmin, Z Achercouk, CE Edling, A Said, K Jeevaratnam Biomolecules 10 (10), 1354, 2020 | 31 | 2020 |
Novel role for matricellular proteins in the regulation of islet β cell survival CL Ryall, K Viloria, F Lhaf, AJ Walker, A King, P Jones, D Mackintosh, ... Journal of Biological Chemistry 289 (44), 30614-30624, 2014 | 25 | 2014 |
Preclinical validation of 3-phosphoinositide-dependent protein kinase 1 inhibition in pancreatic cancer A Emmanouilidi, CA Fyffe, R Ferro, CE Edling, E Capone, S Sestito, ... Journal of Experimental & Clinical Cancer Research 38, 1-12, 2019 | 23 | 2019 |
Haematopoietic progenitor cells utilise conventional PKC to suppress PKB/Akt activity in response to c‐Kit stimulation CE Edling, M Pedersen, L Carlsson, L Rönnstrand, RH Palmer, ... British journal of haematology 136 (2), 260-268, 2007 | 22 | 2007 |
Nuclear export inhibitor leptomycin B induces the appearance of novel forms of human Mdm2 protein S Menendez, M Higgins, RG Berkson, C Edling, DP Lane, S Lain British journal of cancer 88 (4), 636-643, 2003 | 19 | 2003 |
Arrhythmogenic mechanisms of obstructive sleep apnea in heart failure patients KR Chadda, IT Fazmin, S Ahmad, H Valli, CE Edling, CLH Huang, ... Sleep 41 (9), zsy136, 2018 | 16 | 2018 |
Protein expression profiles in murine ventricles modeling catecholaminergic polymorphic ventricular tachycardia: effects of genotype and sex K Saadeh, Z Achercouk, IT Fazmin, N Nantha Kumar, SC Salvage, ... Annals of the New York Academy of Sciences 1478 (1), 63-74, 2020 | 15 | 2020 |
Effects of ageing on pro-arrhythmic ventricular phenotypes in incrementally paced murine Pgc-1β −/− hearts S Ahmad, H Valli, CE Edling, AA Grace, K Jeevaratnam, CLH Huang Pflügers Archiv-European Journal of Physiology 469, 1579-1590, 2017 | 11 | 2017 |
Molecular basis of arrhythmic substrate in ageing murine peroxisome proliferator-activated receptor γ co-activator deficient hearts modelling mitochondrial dysfunction CE Edling, IT Fazmin, K Saadeh, KR Chadda, S Ahmad, H Valli, ... Bioscience Reports 39 (12), BSR20190403, 2019 | 9 | 2019 |
Ageing in Pgc-1β−/− mice modelling mitochondrial dysfunction induces differential expression of a range of genes regulating ventricular electrophysiology CE Edling, IT Fazmin, KR Chadda, S Ahmad, H Valli, AA Grace, ... Bioscience reports 39 (4), BSR20190127, 2019 | 7 | 2019 |
Gene and Protein Expression Profile of Selected Molecular Targets Mediating Electrophysiological Function in Pgc-1α Deficient Murine Atria KR Chadda, CE Edling, H Valli, S Ahmad, CLH Huang, K Jeevaratnam International journal of molecular sciences 19 (11), 3450, 2018 | 6 | 2018 |