Suivre
Gertrudis Rojas
Gertrudis Rojas
Senior researcher and Head of the Protein Engineering Department, Center of Molecular Immunology
Adresse e-mail validée de cim.sld.cu
Titre
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Année
Development and validation of a quantitative ELISA for the measurement of PSA concentration
B Acevedo, Y Perera, M Ruiz, G Rojas, J Benı́tez, M Ayala, J Gavilondo
Clinica chimica acta 317 (1-2), 55-63, 2002
1112002
A simple vector system to improve performance and utilisation of recombinant antibodies
CD Martin, G Rojas, JN Mitchell, KJ Vincent, J Wu, J McCafferty, ...
BMC biotechnology 6, 1-15, 2006
1102006
TCR-like human antibodies expressed on human CTLs mediate antibody affinity-dependent cytolytic activity
P Chames, RA Willemsen, G Rojas, D Dieckmann, L Rem, G Schuler, ...
The Journal of Immunology 169 (2), 1110-1118, 2002
1082002
SARS-CoV-2 RBD-Tetanus toxoid conjugate vaccine induces a strong neutralizing immunity in preclinical studies
Y Valdes-Balbin, D Santana-Mederos, L Quintero, S Fernández, ...
ACS Chemical Biology 16 (7), 1223-1233, 2021
832021
Light-chain shuffling results in successful phage display selection of functional prokaryotic-expressed antibody fragments to N-glycolyl GM3 ganglioside
G Rojas, A Talavera, Y Munoz, E Rengifo, U Krengel, J Ångström, ...
Journal of immunological methods 293 (1-2), 71-83, 2004
722004
Structure and molecular interactions of a unique antitumor antibody specific for N-glycolyl GM3
U Krengel, LL Olsson, C Martínez, A Talavera, G Rojas, E Mier, ...
Journal of Biological Chemistry 279 (7), 5597-5603, 2004
612004
Phage antibody fragments library combining a single human light chain variable region with immune mouse heavy chain variable regions
G Rojas, JC Almagro, B Acevedo, JV Gavilondo
Journal of Biotechnology 94 (3), 287-298, 2002
552002
Functional hierarchy of plasminogen kringles 1 and 4 in fibrinolysis and plasmin‐induced cell detachment and apoptosis
B Ho‐Tin‐Noé, G Rojas, R Vranckx, HR Lijnen, E Anglés‐Cano
The FEBS journal 272 (13), 3387-3400, 2005
442005
Selection of phage-displayed human antibody fragments on Dengue virus particles captured by a monoclonal antibody: application to the four serotypes
S Cabezas, G Rojas, A Pavon, M Alvarez, M Pupo, G Guillen, ...
Journal of Virological Methods 147 (2), 235-243, 2008
432008
Apolipoprotein (a): structure-function relationship at the lysine-binding site and plasminogen activator cleavage site
E Anglés-Cano, G Rojas
Walter de Gruyter 383 (1), 93-99, 2002
432002
Affinity maturation and fine functional mapping of an antibody fragment against a novel neutralizing epitope on human vascular endothelial growth factor
H Lamdan, JV Gavilondo, Y Muñoz, A Pupo, V Huerta, A Musacchio, ...
Molecular BioSystems 9 (8), 2097-2106, 2013
382013
Safety and immunogenicity of anti-SARS CoV-2 vaccine SOBERANA 02 in homologous or heterologous scheme: Open label phase I and phase IIa clinical trials
M Eugenia-Toledo-Romaní, L Verdecia-Sánchez, M Rodríguez-González, ...
Vaccine 40 (31), 4220-4230, 2022
362022
Efficient construction of a highly useful phage-displayed human antibody repertoire
G Rojas, H Lamdan, S Padron, Y Munoz, M Ayala, JV Gavilondo
Biochemical and biophysical research communications 336 (4), 1207-1213, 2005
342005
Baculovirus-free insect cell expression system for high yield antibody and antigen production
J Korn, D Schäckermann, T Kirmann, F Bertoglio, S Steinke, J Heisig, ...
Scientific reports 10 (1), 21393, 2020
322020
High throughput functional epitope mapping: revisiting phage display platform to scan target antigen surface
G Rojas, Y Tundidor, YC Infante
MAbs 6 (6), 1368-1376, 2014
312014
Deciphering the molecular bases of the biological effects of antibodies against Interleukin-2: a versatile platform for fine epitope mapping
G Rojas, A Pupo, K Leon, J Avellanet, T Carmenate, S Sidhu
Immunobiology 218 (1), 105-113, 2013
312013
Fine epitope specificity of antibodies against interleukin-2 explains their paradoxical immunomodulatory effects
G Rojas, Y Cabrera Infante, A Pupo, T Carmenate
MAbs 6 (1), 273-285, 2014
272014
A sandwich ELISA based on anti-apo (a) and anti-apo B monoclonal antibodies for lipoprotein (a) measurement
L Sorell, G Rojas, M Rodríguez, C Ramos, L Torres, MB Torres
Clinica chimica acta 236 (1), 59-70, 1995
261995
Engineering the Binding Site of an Antibody against N-Glycolyl GM3: From Functional Mapping to Novel Anti-ganglioside Specificities
G Rojas, A Pupo, S Gómez, U Krengel, E Moreno
ACS Chemical Biology 8 (2), 376-386, 2013
252013
In-solution buffer-free digestion for the analysis of SARS-CoV-2 RBD proteins allows a full sequence coverage and detection of post-translational modifications in a single ESI …
LA Espinosa, Y Ramos, I Andújar, EO Torres, G Cabrera, A Martín, ...
BioRxiv, 2021.05. 10.443404, 2021
19*2021
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