| Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy SE Logue, EP McGrath, P Cleary, S Greene, K Mnich, A Almanza, ... Nature communications 9 (1), 3267, 2018 | 228 | 2018 |
| Dual IRE 1 RN ase functions dictate glioblastoma development S Lhomond, T Avril, N Dejeans, K Voutetakis, D Doultsinos, M McMahon, ... EMBO molecular medicine 10 (3), e7929, 2018 | 152 | 2018 |
| Endoplasmic reticulum proteostasis in glioblastoma—From molecular mechanisms to therapeutic perspectives J Obacz, T Avril, PJ Le Reste, H Urra, V Quillien, C Hetz, E Chevet Science signaling 10 (470), eaal2323, 2017 | 128 | 2017 |
| Cross-talk between HIF and p53 as mediators of molecular responses to physiological and genotoxic stresses J Obacz, S Pastorekova, B Vojtesek, R Hrstka Molecular cancer 12 (1), 1-10, 2013 | 104 | 2013 |
| CD90 expression controls migration and predicts dasatinib response in glioblastoma T Avril, A Etcheverry, R Pineau, J Obacz, G Jegou, F Jouan, PJ Le Reste, ... Clinical Cancer Research 23 (23), 7360-7374, 2017 | 63 | 2017 |
| Control of anterior GR adient 2 (AGR 2) dimerization links endoplasmic reticulum proteostasis to inflammation M Maurel, J Obacz, T Avril, YP Ding, O Papadodima, X Treton, F Daniel, ... EMBO molecular medicine 11 (6), e10120, 2019 | 58 | 2019 |
| The role of AGR2 and AGR3 in cancer: similar but not identical J Obacz, M Takacova, V Brychtova, P Dobes, S Pastorekova, B Vojtesek, ... European journal of cell biology 94 (3-4), 139-147, 2015 | 50 | 2015 |
| Regulation of tumor–stroma interactions by the unfolded protein response J Obacz, T Avril, C Rubio‐Patiño, JP Bossowski, A Igbaria, JE Ricci, ... The FEBS Journal 286 (2), 279-296, 2019 | 41 | 2019 |
| Anterior gradient protein 3 is associated with less aggressive tumors and better outcome of breast cancer patients J Obacz, V Brychtova, J Podhorec, P Fabian, P Dobes, B Vojtesek, ... OncoTargets and therapy, 1523-1532, 2015 | 25 | 2015 |
| Tamoxifen-Dependent Induction of AGR2 Is Associated with Increased Aggressiveness of Endometrial Cancer Cells R Hrstka, J Podhorec, R Nenutil, L Sommerová, J Obacz, M Durech, ... Cancer Investigation 35 (5), 313-324, 2017 | 23 | 2017 |
| Biological basis for novel mesothelioma therapies J Obacz, H Yung, M Shamseddin, E Linnane, X Liu, AA Azad, DM Rassl, ... British Journal of Cancer 125 (8), 1039-1055, 2021 | 21 | 2021 |
| Use of preclinical models for malignant pleural mesothelioma M Shamseddin, J Obacz, MJ Garnett, RC Rintoul, HE Francies, ... Thorax 76 (11), 1154-1162, 2021 | 19 | 2021 |
| Extracellular AGR3 regulates breast cancer cells migration via Src signaling J Obacz, L Sommerova, D Sicari, M Durech, T Avril, F Iuliano, ... Oncology letters 18 (5), 4449-4456, 2019 | 19 | 2019 |
| Inhibition of METTL3 results in a cell-intrinsic interferon response that enhances antitumor immunity AA Guirguis, Y Ofir-Rosenfeld, K Knezevic, W Blackaby, D Hardick, ... Cancer Discovery 13 (10), 2228-2247, 2023 | 13 | 2023 |
| Novel IRE1-dependent proinflammatory signaling controls tumor infiltration by myeloid cells J Obacz, J Archambeau, D Sicari, PJ Le Reste, R Pineau, S Martin, ... | 4 | 2019 |
| Dual IRE1 RNase functions dictate glioblastoma development S Lhomond, T Avril, N Dejeans, K Voutetakis, D Doultsinos, M McMahon, ... EMBO Molecular Medicine 14 (2), e15622, 2022 | 3 | 2022 |
| Constitutive UPRER activation sustains tumor cell differentiation D Doultsinos, M McMahon, K Voutetakis, J Obacz, R Pineau, P Le Reste, ... | 3 | 2019 |
| IRE1 endoribonuclease signaling promotes myeloid cell infiltration in glioblastoma J Obacz, J Archambeau, E Lafont, M Nivet, S Martin, M Aubry, ... Neuro-oncology, noad256, 2023 | 2 | 2023 |
| IRE1-UBE2D3 signaling controls the recruitment of myeloid cells to glioblastoma J Obacz, J Archambeau, PJ Le Reste, R Pineau, F Jouan, K Barroso, ... bioRxiv, 533018, 2019 | 2 | 2019 |
| Single-cell transcriptomic analysis of human pleura reveals stromal heterogeneity and informs in vitro models of mesothelioma J Obacz, JA Valer, R Nibhani, TS Adams, JC Schupp, N Veale, ... European Respiratory Journal 63 (1), 2024 | 1 | 2024 |
Eric ChevetInserm or Université Rennes 1Adresse e-mail validée de inserm.fr
