|The vascular smooth muscle cell: a therapeutic target in Type 2 diabetes?|
KE Porter, K Riches
Clinical science 125 (4), 167-182, 2013
|Cellular mechanisms by which proinsulin C-peptide prevents insulin-induced neointima formation in human saphenous vein|
RS Mughal, JL Scragg, P Lister, P Warburton, K Riches, DJ O’Regan, ...
Diabetologia 53 (8), 1761-1771, 2010
|Potent suppression of vascular smooth muscle cell migration and human neointimal hyperplasia by KV1. 3 channel blockers|
A Cheong, J Li, P Sukumar, B Kumar, F Zeng, K Riches, C Munsch, ...
Cardiovascular research 89 (2), 282-289, 2011
|Inherent differences in morphology, proliferation, and migration in saphenous vein smooth muscle cells cultured from nondiabetic and Type 2 diabetic patients|
HA Madi, K Riches, P Warburton, DJ O'Regan, NA Turner, KE Porter
American Journal of Physiology-Cell Physiology 297 (5), C1307-C1317, 2009
|Elevated expression levels of miR-143/5 in saphenous vein smooth muscle cells from patients with Type 2 diabetes drive persistent changes in phenotype and function|
K Riches, AR Alshanwani, P Warburton, DJ O’Regan, SG Ball, IC Wood, ...
Journal of molecular and cellular cardiology 74, 240-250, 2014
|Lipoprotein (a): cellular effects and molecular mechanisms|
K Riches, KE Porter
Cholesterol 2012, 2012
|Exploring smooth muscle phenotype and function in a bioreactor model of abdominal aortic aneurysm|
K Riches, TG Angelini, GS Mudhar, J Kaye, E Clark, MA Bailey, S Sohrabi, ...
Journal of translational medicine 11 (1), 208, 2013
|Short-term stimulation of calcium-permeable transient receptor potential canonical 5-containing channels by oxidized phospholipids.|
E Al-Shawaf, J Naylor, H Taylor, K Riches, CJ Milligan, D O'regan, ...
Arteriosclerosis, thrombosis, and vascular biology 30 (7), 1453-1459, 2010
|Chronic hypoxia inhibits MMP-2 activation and cellular invasion in human cardiac myofibroblasts|
K Riches, ME Morley, NA Turner, DJ O'Regan, SG Ball, C Peers, ...
Journal of molecular and cellular cardiology 47 (3), 391-399, 2009
|Hypoxic inhibition of human cardiac fibroblast invasion and MMP-2 activation may impair adaptive myocardial remodelling|
ME Morley, K Riches, C Peers, KE Porter
Biochemical Society Transactions 35 (5), 905-907, 2007
|Type 2 diabetes impairs venous, but not arterial smooth muscle cell function: possible role of differential RhoA activity|
K Riches, P Warburton, DJ O’Regan, NA Turner, KE Porter
Cardiovascular Revascularization Medicine 15 (3), 141-148, 2014
|CCAAT/enhancer binding protein α, β and δ gene variants: associations with obesity related phenotypes in the Leeds Family Study|
CE Bennett, J Nsengimana, JA Bostock, C Cymbalista, TS Futers, ...
Diabetes and Vascular Disease Research 7 (3), 195-203, 2010
|Investigating inherent functional differences between human cardiac fibroblasts cultured from nondiabetic and Type 2 diabetic donors|
B Sedgwick, K Riches, SA Bageghni, DJ O’Regan, KE Porter, NA Turner
Cardiovascular Pathology 23 (4), 204-210, 2014
|Apolipoprotein (a) acts as a chemorepellent to human vascular smooth muscle cells via integrin α V β 3 and RhoA/ROCK-mediated mechanisms|
K Riches, L Franklin, A Maqbool, M Peckham, M Adams, J Bond, ...
The international journal of biochemistry & cell biology 45 (8), 1776-1783, 2013
|Linking energy sensing to suppression of JAK-STAT signalling: a potential route for repurposing AMPK activators?|
C Speirs, JJL Williams, K Riches, IP Salt, TM Palmer
Pharmacological Research, 2017
|Aberrant phenotype in human endothelial cells of diabetic origin: implications for saphenous vein graft failure?|
AC Roberts, J Gohil, L Hudson, K Connolly, P Warburton, R Suman, ...
Journal of diabetes research 2015, 2015
|Therapeutic Targeting of the Proinflammatory IL-6-JAK/STAT Signalling Pathways Responsible for Vascular Restenosis in Type 2 Diabetes Mellitus|
FT Moshapa, K Riches-Suman, TM Palmer
Cardiology Research and Practice 2019, 2019
|The− 1562C/T MMP-9 promoter polymorphism does not predict MMP-9 expression levels or invasive capacity in saphenous vein smooth muscle cells cultured from different patients|
A Maqbool, NA Turner, S Galloway, K Riches, DJ O’Regan, KE Porter
Atherosclerosis 207 (2), 458-465, 2009
|Progressive development of aberrant smooth muscle cell phenotype in abdominal aortic aneurysm disease|
K Riches, E Clark, RJ Helliwell, TG Angelini, KE Hemmings, MA Bailey, ...
Journal of vascular research 55 (1), 35-46, 2018
|MicroRNA‐21 drives the switch to a synthetic phenotype in human saphenous vein smooth muscle cells|
AR Alshanwani, K Riches‐Suman, DJ O'Regan, IC Wood, NA Turner, ...
IUBMB life 70 (7), 649-657, 2018