Suivre
Michal Wegrzynowicz
Michal Wegrzynowicz
Mossakowski Medical Research Centre, Polish Academy of Sciences
Adresse e-mail validée de imdik.pan.pl
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Année
Role of astrocytes in brain function and disease
M Sidoryk-Wegrzynowicz, M Wegrzynowicz, E Lee, AB Bowman, ...
Toxicologic pathology 39 (1), 115-123, 2011
2892011
Synaptic failure and α‐synuclein
L Calo, M Wegrzynowicz, J Santivañez‐Perez, M Grazia Spillantini
Movement Disorders 31 (2), 169-177, 2016
1812016
Depopulation of dense α-synuclein aggregates is associated with rescue of dopamine neuron dysfunction and death in a new Parkinson’s disease model
M Wegrzynowicz, D Bar-On, L Calo’, O Anichtchik, M Iovino, J Xia, ...
Acta Neuropathologica 138, 575-595, 2019
992019
Alpha-synuclein produces early behavioral alterations via striatal cholinergic synaptic dysfunction by interacting with GluN2D N-methyl-D-aspartate receptor subunit
A Tozzi, A de Iure, V Bagetta, M Tantucci, V Durante, A Quiroga-Varela, ...
Biological Psychiatry 79 (5), 402-414, 2016
992016
Disease‐toxicant screen reveals a neuroprotective interaction between Huntington’s disease and manganese exposure
BB Williams, D Li, M Wegrzynowicz, BK Vadodaria, JG Anderson, ...
Journal of neurochemistry 112 (1), 227-237, 2010
752010
Altered manganese homeostasis and manganese toxicity in a Huntington's disease striatal cell model are not explained by defects in the iron transport system
BB Williams, GF Kwakye, M Wegrzynowicz, D Li, M Aschner, KM Erikson, ...
Toxicological Sciences 117 (1), 169-179, 2010
732010
Mechanisms of ammonia-induced cell death in rat cortical neurons: roles of NMDA receptors and glutathione
A Klejman, M Węgrzynowicz, EM Szatmari, B Mioduszewska, M Hetman, ...
Neurochemistry international 47 (1-2), 51-57, 2005
702005
The L444P Gba1 mutation enhances alpha-synuclein induced loss of nigral dopaminergic neurons in mice
A Migdalska-Richards, M Wegrzynowicz, R Rusconi, G Deangeli, ...
Brain 140 (10), 2706-2721, 2017
622017
Disease-toxicant interactions in manganese exposed Huntington disease mice: early changes in striatal neuron morphology and dopamine metabolism
JL Madison, M Wegrzynowicz, M Aschner, AB Bowman
PloS one 7 (2), e31024, 2012
482012
Diabetes-induced changes in glucose synthesis, intracellular glutathione status and hydroxyl free radical generation in rabbit kidney-cortex tubules
K Winiarska, J Drozak, M Wegrzynowicz, T Fraczyk, J Bryla
Molecular and cellular biochemistry 261, 91-98, 2004
422004
Relationship between gluconeogenesis and glutathione redox state in rabbit kidney-cortex tubules
K Winiarska, M Węgrzynowicz, AK Jagielski, J Bryła
Metabolism 52 (6), 739-746, 2003
422003
Gender and manganese exposure interactions on mouse striatal neuron morphology
JL Madison, M Wegrzynowicz, M Aschner, AB Bowman
Neurotoxicology 32 (6), 896-906, 2011
412011
Differential effects of vanadium, tungsten and molybdenum on inhibition of glucose formation in renal tubules and hepatocytes of control and diabetic rabbits: beneficial action …
A Kiersztan, K Winiarska, J Drozak, M Przedlacka, M Wegrzynowicz, ...
Molecular and cellular biochemistry 261, 9-21, 2004
412004
Reduced bioavailable manganese causes striatal urea cycle pathology in Huntington's disease mouse model
TJV Bichell, M Wegrzynowicz, KG Tipps, EM Bradley, MA Uhouse, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (6 …, 2017
392017
Upregulation of cerebral cortical glutathione synthesis by ammonia in vivo and in cultured glial cells: the role of cystine uptake
M Węgrzynowicz, W Hilgier, A Dybel, SS Oja, P Saransaari, J Albrecht
Neurochemistry international 50 (7-8), 883-889, 2007
322007
Endogenous neuroprotectants in ammonia toxicity in the central nervous system: facts and hypotheses
J Albrecht, M Wegrzynowicz
Metabolic brain disease 20, 253-263, 2005
322005
Direct exposure to ammonia and hyperammonemia increase the extracellular accumulation and degradation of astroglia-derived glutathione in the rat prefrontal cortex
W Hilgier, M Węgrzynowicz, J Ruszkiewicz, SS Oja, P Saransaari, ...
Toxicological Sciences 117 (1), 163-168, 2010
292010
Safety, tolerability and pharmacokinetics of the oligomer modulator anle138b with exposure levels sufficient for therapeutic efficacy in a murine Parkinson model: A randomised …
J Levin, N Sing, S Melbourne, A Morgan, C Mariner, MG Spillantini, ...
EBioMedicine 80, 2022
282022
Changes in the striatal proteome of YAC128Q mice exhibit gene–environment interactions between mutant huntingtin and manganese
M Wegrzynowicz, HK Holt, DB Friedman, AB Bowman
Journal of proteome research 11 (2), 1118-1132, 2012
272012
L444P Gba1 mutation increases formation and spread of α-synuclein deposits in mice injected with mouse α-synuclein pre-formed fibrils
A Migdalska‐Richards, M Wegrzynowicz, IF Harrison, G Verona, V Bellotti, ...
PLoS One 15 (8), e0238075, 2020
262020
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